Depression is common and disabling. Modern antidepressants don't always help, but older drugs called MAO inhibitors may work.
How good are GLP-1 agonists? Research suggests semaglutide (Ozempic, Wegovy) helps control weight, glucose and reduces the risk for dementia.
Research shows that certain antidepressants prevent pain relief following surgery. That's because they interfere with powerful analgesics.