logoThe People's Perspective on Medicine
A woman struggling with all her medication, with many pill bottles on her kitchen tableDrug Side EffectsJoe Graedon - July 10, 2023 - 15 comments

Interactions May Have Deadly Results

Millions of people take multiple meds daily. Many of the drugs are not compatible and can lead to dangerous if not deadly complications.

pouring grapefruit juice into a glass
Drug Side EffectsJoe Graedon - February 27, 2023

Is it Risky to Take Atorvastatin with Grapefruit Juice?

Millions of people take statins daily. Are there dangerous food and drug interactions? What about atorvastatin with grapefruit juice?

Angry patient being refused by pharmacist
Drug Side EffectsDennis Miller, RPh - February 16, 2023

What Pharmacists Don’t Tell You

When your pharmacist discusses your drugs with you, you may not learn all the relevant information. Here’s what pharmacists don't tell you.

Fresh baked bran and flax muffin and coffee
Drug Side EffectsJoe Graedon - January 30, 2023

Beware Coffee and Cipro and Other Drug Interactions!

Do you think twice about taking your pills with food or beverages? Coffee and Cipro are NOT a good combination. Beware of other interactions.

Kraken sea monster is also the name for COVID XBB.1.5
COVID-19Joe Graedon - January 12, 2023

Will the Kraken XBB.1.5 COVID Subvariant Get You?

Did you think we were done with COVID? The highly transmissible subvariant dubbed the Kraken XBB.1.5 is spreading fast. How can you avoid it?

a cup of coffee on a saucer
Drug Side EffectsTerry Graedon - December 5, 2022

Thyroid Medicine You Can Take with Breakfast

Liquid or soft-gel thyroid medicine (Tirosint) does not interact with coffee or common breakfast foods as Synthroid does. Consistency is key.

A bottle of cold medicine poured into a spoon
DepressionJoe Graedon - November 28, 2022

Beware of Serotonin Syndrome from Cough Remedy Interaction

Have you ever swallowed cough medicine? A surprising number of drugs can lead to a cough remedy interaction. Serotonin Syndrome can be awful!

Fresh baked bran and flax muffin and coffee
Drug Side EffectsTerry Graedon - November 21, 2022

Drinking Coffee with Synthroid Means the Morning Dose Is No Good

Drinking coffee with Synthroid leads to lower absorption of this thyroid hormone. Fiber and cow's milk also interfere. What's for breakfast?

tylenol bottles
Drug Side EffectsJoe Graedon - October 17, 2022

Tylenol & Alcohol: Acetaminophen Side Effects!

Can you take Tylenol PM and alcohol together? We got spanked by a company spokesman, but the label is confusing! It says to avoid alcohol!

a bottle of Synthroid 175mcg, people on Synthroid, brand name Synthroid thyroid pills
Drug Side EffectsTerry Graedon - October 10, 2022

Do Walnuts Really Interfere with Synthroid Effectiveness?

The manufacturer warns patients that eating walnuts with their medicine could interfere with Synthroid effectiveness.

Pfizer sign outside of company
COVID-19Joe Graedon - September 1, 2022

Is the Oral Pill Paxlovid an Answer to COVID-19?

What should you know about PAXLOVID, an oral medicine against COVID-19? How hard is it to get an Rx? What about dangerous interactions?

Hand with pen drawing the chemical formula of Amiodarone
Arrhythmia (irregular heart rhythm)Joe Graedon - August 28, 2022

Amiodarone Side Effects Can Be Life Threatening

Amiodarone side effects can be lethal. That is why it is imperative that this drug be monitored carefully. Lung toxicity can be irreversible!

Beware of biotin in high doses
Drug Side EffectsTerry Graedon - March 21, 2022

Beware of Biotin Interfering With Thyroid Tests

Doctors and patients should beware of biotin supplements messing up thyroid test results. To avoid a false diagnosis, stop the biotin first.

bottle of magnesium pills
Drug Side EffectsJoe Graedon - February 3, 2022

How Much Magnesium Is Enough?

Getting the optimal magnesium dose every day can be tricky since too little is very dangerous but too much can cause unpleasant GI symptoms.

A very frustrated middle-aged woman pulling her hair out
Drug Side EffectsJoe Graedon - January 24, 2022

Multiple BP Meds leads to Lisinopril and Losartan Risks

Getting blood pressure under 130/80 can be challenging. Taking multiple BP meds is one way. It can also increase the risk for interactions!

a cut on a hand
Atrial Fibrillation (A-fib, arrhythmia)Joe Graedon - August 16, 2021

Beware Mixing Xarelto or Eliquis and OTC Pain Relievers

Many people with AFib are taking drugs like Eliquis or Xarelto. Beware Eliquis and OTC pain relievers! Herbs and some teas can also interact.

young woman with pancreatitis or microscopic colitis
InteractionsJoe Graedon - August 9, 2021

Flagyl | Metronidazole and Alcohol = Disaster!

Can you absorb enough alcohol (ethanol) through the skin to pose a problem? A reader describes a metronidazole and alcohol drug interaction.

Woman in distress covering her ears
DepressionJoe Graedon - December 28, 2020

Bad Mix? Diphenhydramine – Benadryl and SSRI Antidepressants

Many people don't worry about mixing OTC meds and prescription drugs. It might be a bad idea to combine Benadryl with SSRI antidepressants.

An older local pharmacist reads a pill bottle with a discard date
Drug Side EffectsDennis Miller, RPh - September 17, 2020

18 Pharmacists Discuss Their Most Memorable Medication Mistakes

Have you ever gotten the wrong drug from the pharmacy? Here, pharmacists reveal their memorable medication mistakes.

Vitamin B12 (cobalamin) in a syringe ready for injection with vials in the background; Vitamin B12 injections
Drug Side EffectsTerry Graedon - August 31, 2020

Can Prilosec Interfere With Vitamin B12 Injections?

Vitamin B12 injections are a common treatment for pernicious anemia. Injections are not affected by acid-suppressing medicines.

a bottle of Synthroid 175mcg, people on Synthroid, brand name Synthroid thyroid pills
Drug Side EffectsTerry Graedon - March 23, 2020

Could Heartburn Medicine Clash With Thyroid Pills?

PPI drugs for acid reflux like Nexium or Prilosec may interfere with absorption of thyroid pills such as Levoxyl or Synthroid.

doctors performing surgery for appendicitis
Drug Side EffectsTerry Graedon - November 4, 2019

Will Potatoes Slow Your Recovery from Surgery?

Eggplants, peppers, potatoes and tomatoes all can block acetylcholinesterase. This might slow recovery from surgery in which muscle relaxants are used.

pomegranate juice and pomegranate seeds
Drug Side EffectsTerry Graedon - October 28, 2019

Could Pomegranate Juice React Badly with Crestor?

You might worry about whether pomegranate juice will react badly with your medication, but it should not create problems with rosuvastatin (Crestor).

PodcastsTerry Graedon - October 17, 2019

Show 1185: What Are the Risks of Too Many Meds?

Lots of Americans, especially senior citizens, are taking too many meds. This can result in undesirable reactions and dangerous interactions. Can we fix it?

woman appears anxious and depressed
AnxietyJoe Graedon - October 10, 2019

Clonazepam Withdrawal | Safe Sedative or Poison?

Benzodiazepines like alprazolam, clonazepam, diazepam and lorazepam remain popular to ease anxiety. If stopped too quickly, benzos can cause withdrawal!

green capsule containing vegetables and fruits balanced on fingertip
Alternative HealthJeremy Lee - October 7, 2019

Herbal Medicines and Prescription Drug Interactions

Many popular herbal medicines have prescription drug interactions. Learn about them before including both herbs and drugs in your regimen.

green tea being poured from a teapot
Drug Side EffectsTerry Graedon - September 16, 2019

Does Green Tea Interact with Heart Drugs?

How does green tea interact with nadolol? Green tea compounds can lower blood levels of this heart drug, but does not seem to affect metoprolol.

Male doctor and senior female patient discussing osteoporosis drug options
Drug Side EffectsTerry Graedon - July 18, 2019

Will Boniva Interact with Her Pain Reliever?

Does Boniva interact with other medications? This osteoporosis drug together with an NSAID might increase the possibility of digestive tract problems.

A low-carb mixed leaf salad with smoked salmon, spinach, cucumber and onions; eat to lower cholesterol
BleedingJoe Graedon - July 1, 2019

Reversing the Admonition to Avoid Vitamin K with Warfarin

Patients have been told for decades to avoid vitamin K with warfarin. That means no green leafy veggies. But such foods are good for you. What to do?

a bunch of kale, leafy greens
Blood ClotsJoe Graedon - June 13, 2019

Warfarin and Green Leafy Vegetables Can Be OK

Warfarin was the first prescribed anticoagulant. Now we have Eliquis and Xarelto. They're pricey! Is it safe to combine warfarin and green leafy vegetables?

marijuana plants
Drug Side EffectsJoe Graedon - April 18, 2019

Medical Marijuana Users May Require More Anesthesia During Surgery

Millions of people use marijuana. Many rely on cannabis for medical reasons such as nerve pain. People taking marijuana may need more anesthesia than usual.

Drug Side EffectsTerry Graedon - April 15, 2019

What Is the Story on Grapefruit Juice and Meds?

The story on grapefruit juice and medicines can be confusing. The interaction is fairly long-lasting, but only certain drugs interact with grapefruit.