By: Joe Graedon July 6, 2020 17 Comments
    Withdrawal Results from Refusal to Renew Alprazo…

    A caller to our syndicated radio show complained about Xanax withdrawal decades ago. She wanted to stop taking this anti-anxiety agent. When she discontinued the drug, though, she felt awful. She did …

    By: Joe Graedon June 22, 2020 27 Comments
    Zolpidem for Insomnia | COVID-Related Anxiety

    Under the best of conditions, tens of millions of people have trouble getting a decent night’s sleep. These days, though, it’s harder than ever. News about the coronavirus is nonstop. People have …

    By: Terry Graedon March 30, 2020 7 Comments
    How to Sleep During Anxious Times

    In the grip of a terrifying global crisis, insomniacs have a lot of company. Many people who don't normally toss and turn are finding it very difficult to sleep during anxious times such as these. Hav…

    By: Joe Graedon March 9, 2020 14 Comments
    Gabapentin Risks for Persistent Shoulder Pain?

    People in pain are suffering…not just from the pain but also from the treatments that are being offered. Opioids have developed such a terrible reputation that most physicians are reluctant to presc…

    By: Joe Graedon February 24, 2020 16 Comments
    Prednisone Withdrawal: Can You Ever Stop Cortico…

    Corticosteroids are powerful double-edged swords. One side of the blade is beneficial. It can save lives. The other side can do incredible harm. Balancing the benefits against the risks of drugs like …

    By: Joe Graedon October 21, 2019 8 Comments
    Stopping Zolpidem (Ambien) for Insomnia Can Be C…

    Tens of millions of Americans have a hard time getting a good night’s sleep. Based on comments we have read on this website, we would have to say that a lot of people rely on zolpidem to get to slee…

    By: Joe Graedon September 15, 2019 12 Comments
    Stopping Ultracet (Tramadol + Acetaminophen) Led…

    Almost everyone has heard about the opioid epidemic. According to the National Institute on Drug Abuse, “Every day, more than 130 people in the United States die after overdosing on opioids.” …

    By: Terry Graedon August 19, 2019 3 Comments
    Can You Stop Zyrtec Without Horrendous Itching?

    Did you know that certain antihistamines can trigger very unpleasant withdrawal symptoms? Very few doctors are aware that people who stop cetirizine (Zyrtec) or levocetirizine (Xyzal) suddenly may suf…

    By: Joe Graedon June 17, 2019 5 Comments
    Decongestant Spray Addiction is Hard to Kick

    When your nose is stopped up because of a cold or allergies, you feel awful. Breathing through your mouth when you are trying to sleep can be especially challenging. It’s hardly surprising that peop…

    By: Joe Graedon June 6, 2019 23 Comments
    Why Popular Heartburn Drugs PPIs Are Linked to P…

    Millions of people take proton pump inhibitors (PPIs) to suppress the secretion of stomach acid. At last count, doctors wrote over 100 million prescriptions for drugs like dexlansoprazole (Dexilent), …

    By: Terry Graedon May 27, 2019 18 Comments
    Can You Get Off a PPI Without Suffering Heartbur…

    Have you ever tried to get off a PPI like esomeprazole (Nexium) or lansoprazole (Prevacid)? If so, you might have experienced rebound heartburn. People who encounter this problem–and many do–may f…

    By: Terry Graedon May 23, 2019 6 Comments
    Will CBD Help Opioid Addicts Kick Their Habits?

    Cannabidiol, known as CBD, may help opioid addicts kick their habits. Many people are enthusiastic about this compound derived from Cannabis. It is showing up in all kinds of products, mostly without …

    By: Joe Graedon April 4, 2019 25 Comments
    New Concerns About Gabapentin and Pregabalin (Ly…

    A recent review of the FDA’s Adverse Event Reporting System (FAERS) reveals some disconcerting data about commonly prescribed drugs for nerve pain (ISMP QuarterWatch Reports (March 27, 2019). This i…

    By: Joe Graedon April 1, 2019 22 Comments
    Benzodiazepine Dependence | A Hard Habit to Kick

    When most people hear the words “drug abuse” they think of opioids like oxycodone, hydrocodone or heroin. Other contenders include stimulants like cocaine and methamphetamine (“meth”), alcohol…

    By: Joe Graedon March 18, 2019 13 Comments
    How To Stop Venlafaxine: Very, VERY Slowly!

    It has taken the medical profession a very long time to acknowledge that many of the most popular drugs in the pharmacy can cause a kind of dependence. By that we mean such drugs can precipitate serio…

    By: Terry Graedon February 25, 2019 4 Comments
    How to Beat Nose Spray Dependence One Nostril at…

    Decongestant nose spray is fabulous when your nasal passages are so congested you can't breathe. Just a spritz can open clogged sinuses. However, such nasal sprays have a big downside: nose spray addi…

    By: Terry Graedon February 14, 2019 12 Comments
    Show 1153: How to Listen to TV Drug Commercials

    If you watch television, you can’t avoid TV drug commercials for maladies from type 2 diabetes to auto-immune diseases like psoriasis or rheumatoid arthritis to refractory cancers. Do you see these …

    By: Terry Graedon February 7, 2019 38 Comments
    What Is the Other Drug Epidemic?

    Much has been written about the epidemic of opioid drug misuse, overdose and death. With more than 130 people dying every day in this country as a result of opioid overdose, we all have a right to be …

    By: Terry Graedon August 19, 2018 19 Comments
    Can You Overcome an Afrin Addiction?

    Have you ever become addicted to your nasal spray? Millions of people do. Decongestant nasal sprays can be used safely for only a few days before they start to produce rebound congestion that can be q…

    By: Joe Graedon June 25, 2018 19 Comments
    Getting Off Venlafaxine Can Be Incredibly Challe…

    Many years ago we heard from a reader who was trying to get off alprazolam (Xanax). It was not commonly recognized that short-acting benzodiazepines (benzos) could pose unbearable withdrawal symptoms …

    By: Joe Graedon May 28, 2018 35 Comments
    The Zyrtec Itch is Unbearable | Where’s th…

    We first heard about the Zyrtec itch over eight years ago. A reader reported horrible itching within three days of stopping Zyrtec (cetirizine is the generic name for this antihistamine). He reported …

    By: Joe Graedon April 23, 2018 28 Comments
    Why Is Antidepressant Withdrawal So Hard?

    It is estimated that one out of every eight Americans takes an antidepressant medication (JAMA Internal Medicine, Feb. 2017). According to the New York Times, roughly 25 million Americans have been ta…

    By: Terry Graedon February 12, 2018 19 Comments
    Stopping Duloxetine Leads to Terrible Withdrawal…

    Before anyone starts taking an antidepressant, the prescriber should give them some guidance on how to quit. As it turns out, getting off a medication like duloxetine can be extremely difficult becaus…

    By: Terry Graedon January 22, 2018 7 Comments
    How Long Will Dizziness Last After Stopping Lexa…

    It is always smart to have an exit strategy. That is just as true when you begin taking a prescription medication as when you take a new job that might or might not be quite suitable. One reader found…

    By: Joe Graedon November 20, 2017 3 Comments
    Can You Avoid Family Fights Over the Holidays?

    In these highly polarized times, family gatherings like Thanksgiving and Christmas can be stressful. Many people may worry about interacting with relatives whose political views differ. Just thinking …

    By: Terry Graedon November 13, 2017 7 Comments
    How Dangerous Is It to Stop Taking Aspirin?

    Aspirin, a drug that has been easing pain and even saving lives for more than a hundred years, gets very little respect. Perhaps because it is so old or maybe because it is available over the counter,…

    By: Joe Graedon October 5, 2017 15 Comments
    Will Stopping Aspirin Lead to A Heart Attack?

    Many people take low dose aspirin, usually 81 mg, to prevent cardiovascular complications. Doctors frequently prescribe aspirin after a patient has had a heart attack or after a stent has been placed …

    By: Terry Graedon September 10, 2017 9 Comments
    How to Stop an Antidepressant Without Difficulti…

    Have you ever tried to stop an antidepressant abruptly? We have heard from many people who have found that this can trigger an extremely unpleasant experience. They report a discontinuation syndrome t…

    By: Terry Graedon August 20, 2017 8 Comments
    Stopping Cetirizine Led to Itching Like Crazy

    Who would guess that stopping an antihistamine taken for allergies could lead to dramatic hives and itching? Although it may seem improbable, scores of readers report that they developed dreadful itch…

    By: Terry Graedon July 31, 2017 1 Comments
    Could Mom Be Suffering Cough Syrup Withdrawal?

    Stopping certain medications suddenly can lead to symptoms that are extremely uncomfortable. Many readers are familiar with the withdrawal symptoms from pain medicine or antidepressants such as duloxe…

    By: Joe Graedon June 29, 2017 235 Comments
    How To Stop Duloxetine (Cymbalta) Without Withdr…

    From what we hear from readers of our syndicated newspaper column and visitors to this website, most patients are not warned about how to stop duloxetine (Cymbalta). Perhaps the prescriber assumes tha…

    By: Joe Graedon June 12, 2017 24 Comments
    Do Doctors Know How to Help Patients Stop Medica…

    Starting a new prescription is easy. If your doctor tells the pharmacist to write on the label, "take once a day with food," you know exactly what to do. Most people can manage such a simple instructi…

    By: Terry Graedon June 12, 2017 11 Comments
    How Can You Get to Sleep Without Zolpidem?

    Americans tend to be sleep deprived, and the problem may be getting worse. Watching the evening news could be enough to make a person anxious, and anxiety frequently leads to insomnia. No wonder so m…

    By: Joe Graedon June 8, 2017 106 Comments
    How To Stop Tramadol Without Withdrawal Symptoms…

    We have heard from hundreds of visitors to this website about the serious side effects of tramadol (Ultram). They include nausea, vomiting, loss of appetite, constipation, headache, drowsiness, dizzin…

    By: Terry Graedon May 29, 2017 5 Comments
    Can an Antidepressant Really Help with Hot Flash…

    Menopause offers women numerous challenges, but the most significant symptom is probably hot flashes (vasomotor symptoms in doctor-speak). This may also be among the most variable symptoms. Some women…

    By: Terry Graedon May 8, 2017 2 Comments
    How Can You Stop Taking Klonopin for Insomnia?

    When you are feeling stressed and can't seem to get to sleep, medicines can help. Many people have found, however, that it is too easy to rely on a sleep aid. Then, when you no longer feel you need th…

    By: Joe Graedon May 7, 2017 311 Comments
    Serious Tramadol (Ultram) Side Effects & Wi…

    America is undergoing a massive opioid anxiety attack. It has been called an epidemic by lawmakers and the media. While many people used opioids responsibly for chronic pain, there has been substantia…

    By: Terry Graedon April 10, 2017 7 Comments
    Stopping Zyprexa Safely So You Can Lose Weight

    Treating serious mental disorders such as schizophrenia is difficult, so psychiatrists are often willing to accept the side effects and drawbacks of drugs such as aripiprazole (Abilify) or olanzapine …

    By: Joe Graedon March 30, 2017 18 Comments
    Stopping Xyzal Triggers Horrible Itching

    Allergy season has already begun in some parts of the country. Sufferers are reaching for antihistamines to reduce the runny nose and calm the itchy eyes and other pollen reactions. There is a new opt…

    By: Joe Graedon March 6, 2017 23 Comments
    Should You Worry About Kidney Damage with PPI He…

    Proton Pump Inhibitors (PPIs) are incredibly popular. By one estimate, nearly 8% of adults took a prescription drug like esomeprazole (Nexium), lansoprazole (Prevacid) or omeprazole (Prilosec) in the …