By: Joe Graedon October 6, 2016 13 Comments
    Birth Control Hormones Linked to Depression

    For fifty years doctors have been wondering whether hormonal contraception could affect mood. A new study from Denmark suggests that the answer is yes. The researchers reviewed all the records for one…

    By: Joe Graedon October 6, 2016 8 Comments
    Can Psychological Depression Be Triggered By Inf…

    Health professionals have long known that depression can be brought on by challenging life events such as the loss of a loved one, marital difficulties or job loss. Genes can play a role and neuroc…

    By: Joe Graedon August 22, 2016 2 Comments
    Can Ketamine Jump Start Antidepressant Action?

    When people are severely depressed they need immediate help. Sadly, most antidepressant medications take weeks to start working. That's why this reader's question is so very interesting. Q. You've wri…

    By: Joe Graedon August 13, 2016 2 Comments
    Why Did Generic Remeron (Mirtazapine) Disappoint…

    People who are seriously depressed depend upon their medication to get through challenging times. Without a reliable medication they can fall back into a dark depression. This reader shares the frustr…

    By: Joe Graedon August 8, 2016 102 Comments
    Have You Had Problems with Generic Cymbalta (Dul…

    Brand name drugs like Cymbalta have become unaffordable for many patients. That's why most people are dispensed generic Cymbalta (duloxetine). We have received complaints that some generic formulation…

    By: Joe Graedon July 4, 2016 23 Comments
    Abilify Side effects: How Dangerous Are Antipsyc…

    Mental illness has always represented a challenge to the medical community. TV commercials to the contrary, there is no silver bullet to cure anxiety, bipolar disease, major depression or schizophreni…

    By: Joe Graedon June 23, 2016 34 Comments
    Will A Free Lunch Influence Your Doctor’s …

    Ask most physicians whether a free lunch from a drug company would affect their prescribing patterns and the chances are pretty good that they would say no. Some would be highly insulted by the very i…

    By: Terry Graedon April 4, 2016 11 Comments
    How to Fight Depression with a Simple Supplement

    Depression is common, possibly the most common mental illness. According to the CDC, this potentially crippling condition affects almost 8 percent of Americans over 12 years of age (CDC, MMWR, Jan. 6,…

    By: Terry Graedon January 28, 2016 0 Comments
    Pregnant Women Should Be Screened for Depression

    The United States Preventive Services Task Force issues recommendations for screening for a variety of diseases and conditions based on the evidence from studies. Usually these public health messages …

    By: Terry Graedon January 28, 2016 1 Comments
    Teens on Antidepressants Are More Prone to Aggre…

    Questions have been raised in the past about the balance of benefits and risks of antidepressants for youngsters. In fact, a Swedish study published in 2015 showed that people between 15 and 24 were m…

    By: Joe Graedon December 21, 2015 14 Comments
    Billion Dollar Drugs Are Dramatically Disappoint…

    How effective is your medicine? This seemingly simple question is surprisingly complex. In many cases a pill's benefits are barely detectable. Before a drug can be approved by the Food and Drug Admini…

    By: Joe Graedon September 28, 2015 16 Comments
    Antidepressants Linked to Violence: Rape, Robber…

    Q. I am 30 years old and have been taking fluoxetine. I was prescribed this last year because I attempted to take my own life. I have noticed that my behavior, though no longer suicidal, is increasing…

    By: Joe Graedon September 17, 2015 6 Comments
    Is Paxil (Paroxetine) Unsafe for Teens?

    New research suggests that antidepressant medications may pose a serious problem for adolescents. A study from Sweden reveals a relationship between such drugs and violent crimes. More troublesome, a …

    By: Joe Graedon August 19, 2015 2 Comments
    High Glycemic Index Diets Trigger Depression

    What we eat has important effects on our physiology. Should you follow a low-carb or a low-fat diet? The controversy is ongoing. While many nutrition experts maintain firmly that all calories are equa…

    By: Joe Graedon July 16, 2015 3 Comments
    Real World Results Differ from Drug Studies

    People who are recruited to participate in studies of antidepressant medications may not represent typical depressed patients. According to a new study, subjects in clinical trials of antidepressants …

    By: Joe Graedon April 23, 2015 6 Comments
    Mindfulness-Based Therapy Can Help Against Depre…

    People with recurrent depression may benefit from mindfulness-based cognitive therapy, according to a new study. The study took place in England and included 424 people with recurrent major depression…

    By: Joe Graedon April 2, 2015 3 Comments
    Roseroot May Offer Relief for Depression

    Roseroot, also known as Rhodiola rosea, has shown promise in a small study (57 subjects) of depressed individuals. Effectiveness They were randomly assigned to take either the herb, the antidepressant…

    By: Joe Graedon December 11, 2014 1 Comments
    Laughing Gas May Lead to New Depression Treatmen…

    Research on the anesthetic ketamine has shown that it can sometimes produce a quick but not long-lasting remission from otherwise intractable depression. Scientists at Washington University in St. Lou…

    By: Terry Graedon July 21, 2014 2 Comments
    Finding Affordable Treatment for Depression Is a…

    Q. I cannot tolerate oral antidepressant medications because of unacceptable side effects. My doctor has prescribed EMSAM, a skin patch, but it is very expensive. Does this medicine work for depressio…

    By: Joe Graedon July 17, 2014 21 Comments
    Do Doctors, Nurses & Pharmacists Need Educa…

    Modern medicine has shunned its past. There was a time when medical students, nursing students and pharmacy students were taught about herbal medicines. That's because many of the drugs they prescribe…

    By: Terry Graedon July 14, 2014 14 Comments
    Stopping Cymbalta Suddenly Triggered Emotional R…

    Q. Due to a change in my insurance, I wasn't able to refill my prescription for the depression drug Cymbalta. Saturday was my last dose and by Monday I felt like I was losing my mind. Today was the wo…

    By: Joe Graedon April 3, 2014 15 Comments
    Club Drug (Ketamine) Produces Exciting Benefits …

    Doctors are wrestling with the ethical and legal challenges of prescribing ketamine for severely depressed or suicidal patients. The drug may help some people, but doctors worry about the possibility …

    By: Terry Graedon November 21, 2013 6 Comments
    Cognitive Behavioral Therapy for Insomnia Helps …

    Insomnia and depression often go hand in hand. Researchers have wondered whether it's a chicken or egg phenomenon. In other words, does depression trigger insomnia or do sleeping problems contribute t…

    By: Terry Graedon October 31, 2013 1 Comments
    Regular Exercise Helps Prevent the Onset of Psyc…

    There is ample evidence that exercise can be beneficial in treating mild to moderate depression. A new analysis of 30 long-term prospective trials of physical activity and depression found that in the…

    By: Terry Graedon August 19, 2013 24 Comments
    Easing Depression without Drugs

    Q. After taking various antidepressants for many years, I tried to stop. The first time I decreased the levels of medication over five weeks. I experienced many incapacitating withdrawal symptoms and …

    By: Joe Graedon July 29, 2013 289 Comments
    Abilify Side Effects Can Be Scary!

    Abilify (aripiprazole) has been one of the most successful drugs in the pharmacy. At one time, this medication had sales of over $5,000,000,000 annually. That turned it into one of the best selling dr…

    By: Terry Graedon June 10, 2013 8 Comments
    Old Drug Has New Tricks Against Depression

    When someone is severely depressed, immediate action is essential. That's because without help or hope, a suicidal person may do himself irreversible harm. The trouble is that most antidepressant trea…

    By: Terry Graedon June 6, 2013 6 Comments
    Quick Relief from Depression

    An old drug is stimulating a great deal of excitement within the psychiatric community. Ketamine was introduced in the 1970s as an anesthetic. Although it was effective, it had certain drawbacks. The …

    By: Terry Graedon April 22, 2013 40 Comments
    Antidepressant Withdrawal Feels Like Circles of …

    Doctors have been prescribing tranquilizers and anti-anxiety agents for centuries. Antidepressants are more recent. They weren't discovered until the 1950s. When a doctor prescribes anxiolytics or ant…

    By: Joe Graedon November 22, 2012 1 Comments
    Will Fish Oil Fight Postpartum Depression?

    Psychiatrists in Canada have found that low levels of omega 3 fats are linked to a higher risk for postpartum depression. Levels of this critical nutrient drop in the mother during pregnancy while fet…

    By: Terry Graedon August 2, 2012 1 Comments
    Exercise to Combat Depression

    Depression complicates many chronic diseases, making them more difficult to manage and resulting in worse outcomes. But being sick can also make people depressed. A new study from Duke University Medi…

    By: Terry Graedon June 7, 2012 7 Comments
    Telephone Therapy Good Against Depression

    Psychotherapy can be an effective strategy for combating depression, but many people don't have access to a therapist. A new study suggests that telephone counseling can be just as effective as face-t…

    By: Terry Graedon February 6, 2012 4 Comments
    Is Ketamine a Solution for Severe Depression?

    Q. I participated in two clinical trials of ketamine for depression. The infusion was not pleasant, but a few hours later my depression was mysteriously lifted. It was as though someone carefully clea…

    By: Terry Graedon January 26, 2012 1 Comments
    Exercise to Fight Depression

    Chronic illness such as diabetes or heart disease often goes hand-in-hand with depression. What's more, depression makes the outcomes of such chronic conditions worse. Now a new analysis shows that ex…

    By: Joe Graedon January 18, 2012 5 Comments
    Can St. John’s Wort Beat the Blues?

    Q. This time of year, when the weather is bad and there isn't much sunlight, I get really down in the dumps. I have found that St. John's wort can help me out of my funk and it doesn't ruin my sex lif…

    By: Terry Graedon January 9, 2012 1 Comments
    Dealing with Post-Holiday Depression

    The holiday parties are over and far-flung family members have returned to their own homes. The presents have been put away and thank-you notes written. Reality is about to set in. Many of us have gai…

    By: Terry Graedon December 22, 2011 2 Comments
    Questions about Antidepressant Effectiveness

    Antidepressant medications have been controversial for decades. When first introduced, drugs like Prozac were heralded as a major breakthrough in the treatment of depression. More recently, though, ca…

    By: Terry Graedon October 30, 2011 3 Comments
    As Moods Sour, Med Use Soars

    Americans take an amazing number of medications in an attempt to ease their anxiety or relieve their depression. According to our calculations, more than 280 million prescriptions are dispensed annual…

    By: Terry Graedon September 29, 2011 1 Comments
    Coffee Drinkers Less Depressed

    Women who drink a lot of coffee are slightly less susceptible to depression. That's the conclusion from the Nurses' Health Study, which included more than 50,000 women for longer than two decades. The…

    By: Terry Graedon June 22, 2011 9 Comments
    Novel Way to Treat Depression

    Major depression can be very hard to treat. Antidepressant medication can take several weeks to kick in, and not everyone responds favorably to current drugs. An anesthetic called ketamine that has be…