By: Joe Graedon May 30, 2016 18 Comments
    Tremors from Tramadol Could Be Scary Serotonin S…

    Tramadol is becoming a mainstay in the treatment of pain, especially now that opioids have come under such scrutiny. But the FDA warns that this medication can interact with many other drugs to trigg…

    By: Joe Graedon May 9, 2016 6 Comments
    Are You Swallowing A Deadly Drug Combination?

    Americans are swallowing more medications than ever before. A recent nationwide study showed that one in three older people take at least five different prescription drugs (JAMA Internal Medicine, Apr…

    By: Terry Graedon January 11, 2016 11 Comments
    Is Orange Juice Worth the Hassle from His Wife?

    Grapefruit juice has become notorious since the 1991 discovery that drinking grapefruit juice can change the blood levels of certain medications (The Lancet, Feb. 2, 1991). It turns out, however, tha…

    By: Joe Graedon November 30, 2015 12 Comments
    Drug Interaction and Diagnostic Failure Led to D…

    It is far too easy to assume that an over-the-counter medication won't cause any trouble. After all, you don't even need a prescription for it. How risky could it be? Unfortunately, the answer might b…

    By: Terry Graedon November 30, 2015 7 Comments
    Side Effects from Multiple Meds Are Double Troub…

    Next time you go to a pharmacy take a few minutes to do some secret research. Linger around the prescription counter and play detective by observing what happens. If you watch people pick up their pre…

    By: Joe Graedon November 16, 2015 16 Comments
    Are TV Commercials Pushing People To Take Too Ma…

    Americans love their pills. We're taking more medicine now than ever before. Are we taking too many pills? Just watch the evening news or a prime-time television show and you will likely see a variety…

    By: Joe Graedon November 12, 2015 13 Comments
    Doctors Often Ignore Deadly Drug Interaction War…

    The news this week about aggressive control of hypertension (see this news article) will doubtless lead to many more prescriptions for blood pressure medicine. As it is, Americans are taking more medi…

    By: Joe Graedon August 17, 2015 8 Comments
    Medicines that Shift Serotonin Levels Can Cause …

    Serotonin used to be an esoteric term used by neuroscientists to describe a chemical found in the brain, digestive tract and blood. But thanks to drugs like Paxil,  Prozac and Zoloft, this chemical t…

    By: Joe Graedon May 25, 2015 6 Comments
    Turmeric Plus Coumadin Triggered Scary Nosebleed

    Turmeric and its major component curcumin can cause bleeding trouble when combined with drugs used to prevent clotting. It is smart to check on possible interactions before mixing herbs and medication…

    By: Joe Graedon April 27, 2015 3 Comments
    Beware Dangerous Grapefruit Juice Interactions w…

    Grapefruit and grapefruit juice have the potential to interact in a dangerous way with a wide range of medications. It makes sense to ask the prescriber and the pharmacist about this potential. Q. I'v…

    By: Joe Graedon April 23, 2015 21 Comments
    Blood Pressure Drug Combos That Could Be Lethal

    When doctors prescribe blood pressure medication, their goal is to reduce the likelihood that a patient with hypertension will develop heart attacks, strokes, kidney damage, eye problems or even Alzhe…

    By: Joe Graedon March 23, 2015 4 Comments
    Chantix and Alcohol Don’t Mix, Says FDA

    It can take years for the FDA to recognize a drug interaction problem. That's because there is no organized system for anticipating or testing potentially dangerous drug combinations. Alcohol and Chan…

    By: Joe Graedon January 26, 2015 20 Comments
    Simvastatin User Misses His Grapefruit

    Iteractions between food and medicines don't usually get a lot of attention. The exception is grapefruit. People didn't take grapefruit interactions seriously when they were first discovered, but deca…

    By: Joe Graedon January 22, 2015 21 Comments
    Dangerous Interactions with Warfarin (Coumadin) …

    Q. Last year I was diagnosed with atrial fibrillation. I am now on warfarin and understand I will have to take it for the foreseeable future. I have regular blood tests to make sure my blood is clotti…

    By: Joe Graedon January 12, 2015 17 Comments
    Tramadol Interaction with Antidepressants Can Be…

    Q. Recently my husband took tramadol after back surgery. He was also taking an SSRI anti-depressant. He suffered severe hallucinations and sleep-talking throughout the night. The ER doctor suspected s…

    By: Joe Graedon December 11, 2014 25 Comments
    A Deadly Drug Interaction Often Ignored by Docto…

    Combining a common antibiotic with an even more common blood pressure medicine can result in sudden death. The interaction can lead to dangerously high levels of potassium (hyperkalemia) in the body, …

    By: Joe Graedon November 20, 2014 1 Comments
    NSAID with Anticoagulant Raises Risk of Bleeding

    A Danish study has found that a common combination of medications can increase the possibility of serious or even lethal hemorrhage. People with the irregular heart rhythm called atrial fibrillation (…

    By: Joe Graedon November 13, 2014 4 Comments
    Will Your Food Foil Your Medicine? Deadly Drug I…

    Are you taking your medicine correctly? Or are you wasting good money by swallowing your pills with food that can counteract their benefits? Millions of people make mistakes without realizing it. In s…

    By: Joe Graedon November 10, 2014 4 Comments
    Crestor Should Not Be Combined with Red Yeast Ri…

    Q. Is it harmful to take Crestor with red yeast rice? My doctor prescribed Crestor, but I have also been taking red yeast rice. I would like to get my cholesterol level lower so I do not need to take …

    By: Joe Graedon July 17, 2014 21 Comments
    Do Doctors, Nurses & Pharmacists Need Educa…

    Modern medicine has shunned its past. There was a time when medical students, nursing students and pharmacy students were taught about herbal medicines. That's because many of the drugs they prescribe…

    By: Joe Graedon July 3, 2014 31 Comments
    Common Lack of Vitamin B12 Linked to Depression …

    Vitamin deficiencies are supposed to be a thing of the past. But a lack of vitamin B12 may be surprisingly common. Most people don't think twice about this nutrient, also known as cobalamin. Vitamins …

    By: Terry Graedon May 1, 2014 12 Comments
    Taking Herbs or Other Dietary Supplements as Wel…

    One in three Americans takes at least one dietary supplement in addition to a prescription medication. This sets them up for the possibility of a hazardous interaction, according to investigators for …

    By: Terry Graedon April 28, 2014 0 Comments
    Will Ibuprofen Counteract Aspirin’s Cardia…

    Q. Are there problems associated with taking daily low-dose aspirin for cardiac protection along with ibuprofen for pain relief? I've read that taking an NSAID like ibuprofen can negate the desired ef…

    By: Joe Graedon February 13, 2014 22 Comments
    Be VERY Careful About Combining BP Drugs Lisino…

    Blood pressure control is fundamental to keeping your heart, kidneys and brain healthy. But sometimes it is far from easy! Doctors may need to prescribe more than one drug, but combining BP drugs mus…

    By: Terry Graedon January 15, 2014 3 Comments
    Green Tea Interacts with Blood Pressure Pill Nad…

    Those who prefer green tea as their morning beverage have just been warned that the drug can interact with a beta blocker blood pressure medicine called nadolol (Corgard). Ten people were given either…

    By: Terry Graedon January 13, 2014 15 Comments
    Beware Interactions Between Cinnamon and Medicat…

    We often warn patients to be aware of potential interactions among the different medicines they take. That is just as important for those taking dietary supplements. Unfortunately, it can be far more …

    By: Joe Graedon December 19, 2013 21 Comments
    Antidepressant Reacts Badly With Cold Medicine: …

    When you reach for an over-the-counter medicine, do you think about whether it is compatible with other drugs you may be taking? Few people do, but that could be a big mistake. Even cold medicine coul…

    By: Terry Graedon December 5, 2013 2 Comments
    Anti-inflammatory Drugs Linked to Low Levels of …

    People with arthritis frequently take nonsteroidal anti-inflammatory drugs such as ibuprofen, naproxen or Celebrex for pain relief. A new study suggests, however, that long-term use of such medication…

    By: Terry Graedon November 18, 2013 3 Comments
    Are Uncle’s Medications Contributing to hi…

    Q. My uncle lives alone and is about to turn 86. He is part of a generation that goes to the doctor regularly and takes whatever is prescribed without question. He has been dizzy lately and has had a …

    By: Terry Graedon September 16, 2013 2 Comments
    Drugs for Depression and Migraine Headaches Hold…

    Q. I have suffered with both migraines and depression for years. My doctor prescribed Cymbalta for the depression, sumatriptan for the migraines, Provigil to stay awake during the day and trazodone to…

    By: Joe Graedon August 19, 2013 37 Comments
    Celebrex Side Effects & Interactions Are Sc…

    If you watch television you have probably seen the current Celebrex commercial. It starts with a picture book of a woman sitting in a lounge chair at the beach waving to friends. The pages flip quickl…

    By: Joe Graedon August 15, 2013 149 Comments
    Eliquis (Apixaban) Side Effects & Interacti…

    Q. I have been taking Coumadin (warfarin) for years, however, my doctor recently recommended that I switch to Xarelto or Eliquis. I am looking for more information on Eliquis to evaluate the pros and …

    By: Terry Graedon July 29, 2013 3 Comments
    Drug Interactions Making Mom Dizzy

    Q. My mom has always been active and engaged but lately she seems to be fading and confused. She constantly complains of being dizzy or light-headed. She also has ringing in the ears and insomnia. Her…

    By: Joe Graedon July 18, 2013 39 Comments
    Enbrel & Remicade Side Effects & Compl…

    Autoimmune conditions such as rheumatoid arthritis and psoriatic arthritis can turn moving into misery. These conditions are far worse than aching joints; in some cases, they can be crippling. For cer…

    By: Joe Graedon July 1, 2013 27 Comments
    Juice and Pills Can Be a Deadly Mix

    Speed kills, especially when it comes to pills. Everyone is in such a hurry these days that it's rare for physicians to provide detailed instructions about how to take prescribed medicine. You probabl…

    By: Joe Graedon June 20, 2013 20 Comments
    Warfarin (Coumadin) Side Effects & Interact…

    Warfarin remains an important drug for preventing blood clots that can cause heart attacks and strokes. This anticoagulant is tricky, though. It can interact with dozens of other medications and even …

    By: Terry Graedon June 10, 2013 11 Comments
    Medications Sapping His Energy

    Q. My husband takes blood pressure medicine (lisinopril, carvedilol, clonidine and amlodipine). In addition, he takes amiodarone and Plavix for his heart. I believe that some of these drugs are wiping…

    By: Terry Graedon May 20, 2013 4 Comments
    Could Curry Counteract Clotting?

    Q. I was searching for natural asthma relief and read that turmeric could tame wheezing. This is the main ingredient in curry powder. I have been swallowing spoonsful of them both for several days. I …

    By: Joe Graedon April 11, 2013 36 Comments
    Amiodarone: Cancer, Thyroid & Other Side Ef…

    Irregular heart rhythms can be very scary. So too are the drugs that treat these arrhythmias. That's because anti-arrhythmic medications often come with a long list of serious side effects. This is es…

    By: Terry Graedon March 25, 2013 12 Comments
    Doctors Overlooked Scary Drug Interaction

    Q. I have been diagnosed with serotonin syndrome brought on by a drug interaction between Cymbalta, gabapentin, tramadol and a low dose of Prozac. It caused me a lot of problems, including agitation, …