Hypothyroidism is a condition in which the thyroid gland can’t produce enough thyroid hormones to keep metabolism normal throughout the body. This problem is surprisingly common, affecting nearly 5 percent of US adults. Doctors generally treat it by prescribing levothyroxine, also known as T4. You may recognize some of the brand names for levothyroxine, such as Levothroid or Synthroid. For many people, levothyroxine works well, but some individuals don’t thrive on it. They continue to have symptoms such as fatigue, depression, heavy menstruation or sensitivity to cold. Do they feel better if they take Armour Thyroid instead?
Could Armour Thyroid Help More Than Levothyroxine?
Q. I took levothyroxine for 20 years after I developed hypothyroidism. My dosage kept increasing and then the doctors started decreasing it.
Despite constant monitoring, I was now showing signs of fatigue and an unexpected weight gain. My doctor suggested switching to Armour thyroid. What a difference! I am back to feeling good again, not drained or fatigued, and the weight dropped off immediately. I changed nothing in my usual lifestyle except starting Armour thyroid.
A. Until quite recently, doctors believed that hypothyroid patients needed only levothyroxine (Synthroid, aka T4). Most people convert T4 to the active hormone triiodothyronine (aka T3) through the enzyme thyroid deiodinase. Research now shows that some individuals have genetic variants of deiodinase that are less efficient (Current Opinion in Endocrinology, Diabetes, and Obesity, Oct. 2018). Such patients often feel much better on a regimen that provides T3 as well as T4. Thyroid extract like Armour Thyroid or Nature-Throid contain both.
What Is the Difference Between Armour Thyroid and Levothyroxine?
Q. I was on levothyroxine for about 30 years, and then I started having really bad side effects. It made me itch all over, as if bugs were biting me. Heartburn was a constant torment and my hair was falling out.
My doctor suggested Armour Thyroid, which is all natural. It has made a huge difference.
Thyroid Function Test Results:
Before I started on Armour, I stopped taking the levothyroxine for a couple months. By the end of that time I felt really lousy, so I had blood work done. My TSH was 114.4. After taking Armour for six weeks, my level is in the middle of the normal range and I feel good.
Who Might Benefit Most from Armour Thyroid?
A. Levothyroxine (Levoxyl, Synthroid, Tirosint, Unithroid) is a synthetic T4 thyroid hormone. Armour Thyroid is made from dried pig thyroid glands. In contrast to levothyroxine, Armour provides both T3 and T4 hormones.
The thyroid hormone that is active in body tissues is T3. Normally, T4 is converted to T3 to provide what the body needs. That is why doctors prescribe stand-alone T4 (levothyroxine). In fact, most people with hypothyroidism do well enough taking this drug alone.
Some people are less efficient at this conversion, however (Abdalla & Bianco, Clinical Endocrinology, Nov. 2014). They often feel better on a combination of the two hormones. You may be one of these. That could explain why Armour Thyroid made such a difference for you. Up to one-fifth of patients with hypothyroidism might benefit from such a combination (Welsh & Soldin, European Journal of Endocrinology, Dec. 2016). A review of the medical literature concludes that people who have persistent symptoms even though TSH levels are normal may need an individualized treatment plan (Journal of Clinical Endocrinology and Metabolism, Sep. 1, 2020).
We discuss the symptoms of hypothyroidism, the pros and cons of natural vs. synthetic thyroid hormone treatment and how to interpret lab results in our eGuide to Thyroid Hormones. Not all endocrinologists are enthusiastic about Armour Thyroid, and this online resource explains why. By reading it, you’ll also learn about the various ways people like you can get the extra T3 hormone their bodies need.
You may also be interested in Show 1015: Thyroid Mysteries, Controversies and the Latest Research. In it, Dr. Antonio Bianco explains the results of his studies on the enzymes that convert T4 to T3, and patient advocate Mary Shomon describes how to feel good despite thyroid dysfunction.
In another podcast, Dr. Bianco explains treatment for people who are not responding as expected to levothyroxine alone. It is Show 1196: What to Do If Thyroid Treatment Doesn’t Work for You.