Will Bromelain from Pineapple Ease Aching Joints?

What can you do for the aching joints of arthritis or the sore muscles and soft tissue of fibromyalgia? Many sufferers are caught in a difficult dilemma: without relief for the pain, they have trouble moving, exercising or just living their lives. On the other hand, the medications that can offer pain relief may have intolerable side effects. NSAIDs have a litany of undesirable actions, from the well-known digestive tract irritation to less well-recognized cardiovascular complications or kidney injury. Additionally, drugs for fibromyalgia, including duloxetine (Cymbalta), milnacipran (Savella) and pregabalin (Lyrica), have some challenging adverse effects. Are there any natural compounds, such as bromelain or boswellia, that could offer pain relief? Do they fight inflammation? Some readers are enthusiastic.

Fresh Pineapple Against Arthritis Pain

Q. Please remind everyone that fresh pineapple can reduce arthritis symptoms! I have eaten it regularly for years and had very little arthritis. Recently I stopped eating it for couple of weeks and got horrible pain and stiffness in my hands.

I vaguely remembered something about pineapple and looked it up. Sure enough, there it was in your book.

A. Most chemists attribute the anti-inflammatory power of pineapple to its bromelain content (Nutrients, June 28, 2024).  This is a natural mix of enzymes that can break down proteins. It has a long history of use for wound healing and controlling inflammation. In one study, bromelain combined with two other natural products reduced pain and swelling following hip or knee replacement surgery (Nutrients, Dec. 5, 2025).

We discuss a range of natural approaches for easing joint pain in our book, The People’s Pharmacy Quick & Handy Home Remedies. We are delighted that you found this one useful.

The Benefits of Bromelain

Q. I am an advanced practice registered nurse with ailing joints and suspected fibromyalgia. Does it make sense to try bromelain or other anti-inflammatory enzymes?

A. Bromelain is a mixture of enzymes extracted from pineapple. It has been used to promote wound healing and fight inflammation (Biomedical Reports, Sep. 2016). This natural product dampens the activity of cyclooxygenase-2 (COX-2) somewhat like celecoxib does. The pineapple enzymes seem to have fewer side effects, however.

In addition, research shows that volunteers taking bromelain got as much pain relief for their arthritic knees as those taking the prescription NSAID diclofenac (Clinical Rheumatology, Oct. 2016). Moreover, bromelain together with other natural enzymes was as effective as diclofenac for jaw arthritis pain (Journal of Clinical and Diagnostic Research, June 2017).

Bromelain and Fibromyalgia

We could not find research evaluating the use of bromelain to ease the pain of fibromyalgia. Anecdotally, one physician who also suffers fibromyalgia suggests taking the anti-inflammatory spice turmeric. In addition, she recommends myofascial release and topical creams containing arnica or capsaicin, the hot stuff in hot peppers. A review of treatments for chronic pain found evidence for capsaicin (Swedish Council on Health Technology Assessment, Oct. 2006). You will find additional information on this compound in Alternatives for Arthritis.

Finally, some people with fibromyalgia use acupuncture to get pain relief. While it may not be adequate on its own, this could be a part of a natural treatment regimen.

Bromelain to Ease Inflammation

Q. I gave my children pineapple juice the day before they had their wisdom teeth extracted and while they were recovering. The swelling was considerably less than without the juice.

One kid complained about the juice, thinking it wasn’t doing any good since she still had some swelling. Then she saw a friend who had had her wisdom teeth out a couple of days before my daughter. The friend’s swelling was still much worse. After that, my daughter didn’t complain any more.

A.  Bromelain, a compound from pineapple, is recognized for its anti-inflammatory activity. Dentists have found that pineapple extracts combined with aloe vera gel reduces pain following tooth extraction (Journal of Clinical and Experimental Dentistry, July 1, 2024).

Learn More:

You can learn more about natural anti-inflammatory compounds in our book, The Graedons’ Guide to Alternatives for Arthritis.

You might also be interested in the book we mentioned previously, The People’s Pharmacy Quick & Handy Home Remedies.