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Exercise Is Effective Treatment for Psychological Depression

Many studies demonstrate that exercise is effective in treating depression. Now research show that active older people prevent depression.

Exercise may help people overcome mild to moderate depression. Previous studies have shown that younger and middle aged people benefit. (Keep reading for more details on those.) Now we have evidence that exercise is effective even for those who are older than 50.

Learning That Exercise Is Effective Against Depression in Seniors:

More than 4,000 participants in the Irish Longitudinal Study on Ageing answered questions about physical activity and mood every two years between October 2009 and December 2018. Those who exercised at least 20 minutes a day, at least five days a week, reduced their chance of experiencing depression by approximately 16 percent compared to those who were not active at all (JAMA Network Open, July 10, 2023). People who exercised more frequently, for a longer time period or more vigorously got more benefit, reducing their chance of depression by as much as 42 percent.

Previous research has shown that regular exercise works at least as well as medication against depression. This study confirms that exercise is effective, particularly for people with conditions like heart disease that can lead to depression. The researchers point out that 20 minutes five days a week is a lower “dose” than international public health organizations like WHO recommend for general health.

The investigators conclude,

“The findings of this cohort study suggest that physical activity doses lower (ie, 400 to <600 MET-min/wk) than doses recommended in guidelines for overall health (ie, 600 MET-min/wk) may protect against depressive symptoms and major depression among older adults.”

Previous Research Showing That Exercise Eases Depression:

Several meta-analyses have consolidated evidence from a number of randomized controlled trials. All of them found that physical exercise is effective in treating depression.

One study analyzed data from 35 trials that randomly assigned people to either exercise or control groups (The Cochrane Library, online, Sept 11, 2013). In these trials, exercise was roughly equivalent to antidepressant medication or psychotherapy in reducing depression symptoms. For example, in one study more than half of the older depressed patients who were randomized to an exercise program improved their mood, whereas only a third of the patients who went to informational talks experienced improvement. The collective research suggests that the more intense and regular the exercise, the greater the benefit.

Exercise Works Better Than Nothing:

A few years later, another meta-analysis included 23 randomized controlled trials (Journal of Affective Disorders, Sep. 15, 2016). Compared to no intervention, exercise had a significant positive effect. In comparison, trials comparing exercise to usual care found only a moderate effect size. The benefits of exercise over antidepressant medication in this analysis was small and not significant.

Nonetheless, the authors concluded:

“Physical exercise is an effective intervention for depression. It also could be a viable adjunct treatment in combination with antidepressants.”

Exercise Is Effective in Re-wiring the Brain:

A relatively recent review presented evidence that aerobic exercise, resistance exercise and mind-body exercise can all improve depressive symptoms (CNS Neuroscience & Therapeutics, Sep. 2020). The investigators suggested that physical activity can change the structure of the brain. We don’t know if this explains why exercise works as well as it does.

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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Citations
  • Laird E et al, "Physical activity dose and depression in a cohort of older adults in The Irish Longitudinal Study on Ageing." JAMA Network Open, July 10, 2023. doi:10.1001/jamanetworkopen.2023.22489
  • Cooney GM et al, :Exercise for depression." Cochrane Database of Systematic Reviews, Sep. 12, 2013. https://doi.org/10.1002/14651858.CD004366.pub6
  • Zhao J-L et al, "Exercise, brain plasticity, and depression." CNS Neuroscience & Therapeutics, Sep. 2020. DOI: 10.1111/cns.13385
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