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Getting Off PPIs

Q. Do you have a diet for helping me survive omeprazole detox? Your book alerted me to the dangers of the drug and I want to end my dependence on this heartburn medicine.

When I forgot to take omeprazole two days in a row, I experienced hell. I tried to stop the drug earlier, but could only make it one week before the heartburn became unbearable. Now I can’t be off it for one day without wanting to die.

A. People who take powerful acid-suppressing drugs (proton-pump inhibitors or PPIs) such as omeprazole (Prilosec), lansoprazole (Prevacid) and esomeprazole (Nexium) often have difficulties with rebound acidity if they stop suddenly. A study done in healthy volunteers without heartburn showed that exposure to this kind of medicine can precipitate symptoms such as indigestion and acid regurgitation (Gastroenterology, July, 2009).

Make sure to check in with your doctor before you you try getting off PPIs. To get off it, you will want to taper down gradually. There are instructions for a 6-week plan and a recipe for Persimmon-Ginger Tea to ease heartburn in the Guide to Digestive Disorders we are sending you.

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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