The People's Perspective on Medicine

Will Taking Pycnogenol Help Heal Eczema?

One reader reports that the supplement Pycnogenol essentially eliminated chronic eczema. Basic research suggests this antioxidant could have benefit.
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Eczema is a very common and often extremely annoying skin condition. Sufferers complain of a red itchy rash along with very dry skin. They may have particular trouble with places where the skin folds frequently, such as the inner elbows or the backs of the knees. Others find that eczema on the hands is persistent and difficult to treat. One reader found a supplement that helps. Will Pycnogenol® help you, too?

Could Pycnogenol Clear Up Eczema?

Q. I read that Pycnogenol could help heal eczema. I’d been struggling with this skin condition for months, so I bought some and started taking it. Within a couple of months, my eczema was gone. Do you know if I need to keep taking it every day, or only when I have another flare-up?

A. We appreciate your report. Pycnogenol is a compound derived from French maritime pine bark with antioxidant and anti-inflammatory activities.

Lack of Clinical Trials on Pycnogenol:

We could find no clinical trials of Pycnogenol for eczema, but scientists have confirmed that it calms inflammation in skin cells called keratinocytes (Free Radical Biology and Medicine, Jan. 2000). They believe that Pycnogenol has great potential for treating people with inflammatory skin disorders.

In addition, investigators have determined that this dietary supplement can improve skin barrier function (Skin Pharmacology and Physiology, Jan. 2016). Usually, more robust barrier function means less eczema. That is why we have been enthusiastic about moisturizers containing urea. This compound also improves the barrier function of the skin.

A Looming Experiment:

Unfortunately, however, we don’t have an answer to your question. If you experiment on yourself, please let us know what you learn.

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    About the Author
    Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies. .
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    Citations
    • Bito T et al, "Pine bark extract pycnogenol downregulates IFN-gamma-induced adhesion of T cells to human keratinocytes by inhibiting inducible ICAM-1 expression." Free Radical Biology and Medicine, Jan. 2000. DOI: 10.1016/s0891-5849(99)00229-4
    • Grether-Beck S et al, "French maritime pine bark extract (Pycnogenol®) effects on human skin: Clinical and molecular evidence." Skin Pharmacology and Physiology, Jan. 2016. DOI: 10.1159/000441039
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    Might it help chronic plaque psoriasis?

    I use a teaspoon of yellow mustard for heartburn with a glass of water, and it works every time for me. I go back to bed and sleep.

    * Be nice, and don't over share. View comment policy^