The People's Perspective on Medicine

Lisinopril Side Effects Can Be Lethal

Blood pressure pills like Lisinopril are perceived as generally safe medications, but mysterious lisinopril side effects called angioedema can be life threatening.
Lisinopril, ACE inhibitor

How do you keep your blood pressure under control? Managing blood pressure is an important pillar for maintaining good health and reducing the risk of strokes or heart disease. Regular exercise, a diet high in healthful vegetables and fruits and ways to relax and manage stress can help. But sometimes people need blood pressure medication to get hypertension into bounds. Lisinopril is one of the most popular prescription pills for hypertension, but what about lisinopril side effects?

ACE Inhibitors for Blood Pressure Control:

Blood pressure pills are perceived as generally safe medications. ACE (angiotensin converting enzyme) inhibitors in particular are considered highly effective with few adverse reactions. We calculate that at least 100 million prescriptions are filled for ACE inhibitors each year. Here is a list of commonly prescribed ACEi drugs:

ACE Inhibitors:

  • Benazepril (Lotensin)
  • Captopril (Capoten)
  • Enalapril (Vasotec)
  • Fosinopril (Monopril)
  • Lisinopril (Prinivil, Zestril)
  • Moexipril (Univasc)
  • Perindopril (Aceon)
  • Quinapril (Accupril)
  • Ramipril (Altace)
  • Trandolapril (Mavik)

We have frequently written about an ACEi cough. This lisinopril side effect drives many patients crazy because it can keep them awake at night, cause incontinence and make them miserable. This is not a minor side effect. Some people throw up because of an ACEi-induced cough. Here are just a few stories:

Wendy had no idea her BP medicine could cause a cough:

I have been coughing to the point of vomiting for the last two years. My primary said it was post nasal drip, asthma or heartburn. When none of those proved true, I called an allergist who asked me right over the phone about my BP meds. I called back my GP and he said, Oh yes, that drug causes cough too! I could have screamed!”

D. Jones had the cough from hell:

I was taking lisinopril for about three months. It was crazy. The coughing was sooooo bad I too was unable to sleep or eat. My body was hurting all over and the coughing was so bad I started gagging with violent coughing spells. My back felt like someone was stabbing me with a knife. My body almost shut down. I was not able to sleep for three days, I was having panic attacks and was unable to eat.

“My husband and daughter stayed home for three days to take care of me. On the third day my doctor was able to see me. By that time my body was so weak and my skin was pale that it was hard to get dressed (THANK GOD for a wonderful husband). I had reached out to all my family and friends and asked them to pray for me. I was thinking… am I going crazy? I was not able to stop crying maybe due to no sleep or food.

“When my doctor walked in the room she was so surprised to see how I looked. My husband was very upset my doctor just said the coughing was from lisinopril but not the other symptoms.

“I have been off Lisinopril for two weeks now. WOW!!! I feel GREAT! No back pain, very little coughing and lots of sleep.”

Lisinopril Side Effects Can Be Life Threatening:

A lisinopril cough can ruin the quality of your life. It can disrupt sleep and lead to lots of other complications. It is rarely lethal. A far more worrisome lisinopril side effect is called angioedema. It can be life threatening.

A Turkish patient died from angioedema triggered by lisinopril despite emergency treatment (Iranian Journal of Allergy, Asthma, and Immunology, Dec., 2015).

We received the following message from Gary, a visitor to this website.

“One night after taking lisinopril my lips began to swell as if I had a fever blister. Within two hours my face was extremely swollen and my throat began to feel like it was closing off my air passage. I went to the hospital and spent the night in the emergency room with an IV and other meds.

“The doctors identified that I had a reaction from the lisinopril. I still had some swelling a full 24 hours after the incident. I was told that I was lucky and that they were close to doing a tracheotomy.

“I had taken lisinopril for four years before the reaction. I would strongly advise alternative medications other than lisinopril, and recommend anyone who has been taking this for any length of time have a discussion with their physician.

“The final advice I have is that if you have a bad reaction, seek medical attention immediately.” Gary

Angioedema and Other Lisinopril Side Effects:

Angioedema is a somewhat mysterious reaction to ACE inhibitor blood pressure pills. It can happen within the first few days or weeks of starting treatment, or, as in Gary’s case, show up after years of taking the medication. There is no way to predict what will trigger such a hazardous reaction. When it happens, however, it requires emergency medical attention. If your airways close, breathing becomes impossible. That is why they were considering an emergency tracheotomy in Gary’s case.

Dee in Menifee, California had to have two tracheotomies:

I had been taking Lisinopril for 13 years. Over the last 5  years I had allergic reactions to what I thought were nuts. My left jaw would begin swelling in the middle of the night. The swelling would spread to my upper lip. The swelling would last up to 3 days.

“On Dec. 30th 2017, around 8 pm, I had a sensation in the interior of my jaw that felt like a sore throat was coming on. Around 10 pm, I felt a hard knot in my left jaw area. Around 10:30 my throat felt swollen. I drove to the nearest emergency room and waited to be seen.

“By the time I was seen, my tongue was swollen to the point that I could barely talk. They tried to intubate but my throat and tongue were too swollen. they performed a tracheotomy on me. My husband said that I was transferred to my hospital the following day where they waited for the swelling to go down to perform a second tracheotomy.

“I woke up 3 days later in intensive care not knowing what had happened. I spent a horribly uncomfortable week in the hospital and am still recovering after week 5. I may need to go back to have some cartilage repaired and some laser treatment for scar tissue removal.

“While in the ER, a nurse asked my husband if I was on lisinopril and if so, to stop taking it as she was aware of other people who had experienced the same reaction. A family member who is a nurse asked the same question and suggested we look into the side effects of taking lisinopril.

“Since then, we have spoken to two people who had been on lisinopril, one for over 20 years, and experienced the same reaction that I had. I am glad that we found out what caused the reaction. It was a frightening experience for myself and my family.”

person holding their stomach in pain, calm chronic diarrhea, IBS, low FODMAP diet

Lisinopril Side Effects in the Digestive Tract:

Angioedema doesn’t always affect the face, tongue and neck, though. We have heard from other visitors that ACE inhibitors can also affect the belly. Here is one poignant story:

I was put on lisinopril for high blood pressure in January. That month I experienced severe stomach cramping and vomiting. I was rolling on the floor in agony. The doctor said it was most likely the flu but started me on two different antibiotics in case it was bacterial.

“A few weeks later I had another attack with severe stomach cramping and vomiting. I went to the ER, where I was given IV pain meds. A CT scan showed small intestine inflammation partially blocking off my bowel. I was sent home but returned the next day with pain that was a 10 on a 10-point scale. The doctor said that all the tests had been done and there was nothing he could do. I was sent home with pain medication.

“A few weeks later I was admitted to the hospital with increased small intestine inflammation and another blockage. I vomited and dry-heaved for 12 hours. I was released four days later with no definitive diagnosis.

“I was told most likely I had Crohn’s disease, but a colonoscopy was negative for Crohn’s. I underwent extensive tests, including endoscopy, and all were negative. None of the doctors made a connection with the drug lisinopril.

“After two months of missing work, three more ER visits and untold suffering, I found several other people who reported similar symptoms connected to lisinopril. I stopped the medication and have not had another attack. If you look on PubMed you can see reports on lisinopril and intestinal angioedema, but doctors don’t think to connect this with lisinopril because it is not listed as a common side effect.” 

Angioedema of the Abdomen:

Many physicians are aware that ACE inhibitors can cause angioedema in the lips, mouth and throat. Lisinopril side effects are not restricted to the upper airways, though. An equally serious c0mplication that often goes misdiagnosed for weeks or months involves angioedema of the abdomen (Journal of Emergency Medicine, April, 2016; GE Portuguese Journal of Gastroenterology, Dec. 2, 2015; Postgraduate Medicine, March, 2015). It too can be life threatening if the bowels become obstructed. Here is one story to help you understand the gravity of this condition:

Monique in Missouri was rushed to the hospital with abdominal angioedema:

On December 15, I had to be taken to the ER due to really bad stomach pains. The pains I felt were worse than labor pains. It felt like someone was stomping on my intestines with high heel shoes on.

“Once admitted, the doctors ran all of the tests including colonoscopy, upper GI, and different blood tests. Everything the doctors were looking for came back negative. While in the hospital they kept giving me my blood pressure med, lisinopril. My lips became swollen while I was there and I was told it was because of the test I had done earlier. I replied, ‘no something is not right,’ but they continued to say I was ok, it’s because of the test.

“I suffered in pain for a week and 2 1/2 days while lying in the hospital. The doctors could not find or figure out was going on and said ‘we feel like it would be safe to send you home.’ They then released me from the hospital with instructions, a 2 week follow up appointment and another colonoscopy and also with an added blood pressure pill to go with the lisinopril.

“Once at home I continued taking my blood pressure pills according to the doctors directions. The pain, vomiting, diarrhea and the horrible coughing, continued. I began having chest pains and shortness of breath, I thought it was because I was trying to do too much to fast.

“On January 17 my upper lip started to swell and later that night it got worse. The next day when I woke up I looked horrible. My face, upper lip and neck were swollen even more. I returned to the ER that’s when the ER Doctor said I was having an allergic reaction to the lisinopril. They began to give me steroids and other meds to stop what was going on and to keep my throat from swelling up as well. They then released me with a prescription for a 3 day steroid fix. I could have died. Feeling safe enough to send me home the first time almost cost my life.”

Taking ACE Inhibitors for Hypertension:

ACE inhibitors can be very effective medications for many people. As long as you don’t experience an unrelenting cough, breathing difficulties or severe abdominal discomfort, you may be home free. Nevertheless, it is essential to know about other lisinopril side effects. No medicine should ever be stopped without medical supervision.

Here are some other lisinopril side effects to aware of.

Lisinopril Side Effects:

  • Dry cough, uncontrollable cough, nausea, vomiting
  • Dizziness, excessively low blood pressure
  • Kidney function changes, BUN & creatinine elevations
  • Headache
  • Digestive distress, diarrhea, abdominal pain
  • Tiredness, fatigue, malaise
  • Excessive potassium levels (requires immediate medical attention!), irregular heart rhythms, chest pain
  • Elevated uric acid levels
  • Sensitivity to sunlight (photosensitivity), skin rash
  • Angioedema (swelling in abdomen, severe abdominal pain)
  • Severe allergic reaction (anaphylaxis) requiring emergency treatment
  • Toxicity to liver or pancreas
  • Blood disorders
  • Potential birth defects if taken during early pregnancy
  • Sexual difficulties

In one case report, lisinopril caused hair loss (Journal of Pharmacy Practice, online June 6, 2016). Anyone who would like to learn more about non-drug approaches to controlling hypertension may find our Guide to Blood Pressure Treatment of interest. There is also information about other medications for dealing with blood pressure problems.

Share your own experiences below. Those who would like to learn more about ACE inhibitor cough will find this link of great interest.

When Will Doctors Pay Attention to an ACE Cough?

Revised 2/8/18

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About the Author
Joe Graedon is a pharmacologist who has dedicated his career to making drug information understandable to consumers. His best-selling book, The People’s Pharmacy, was published in 1976 and led to a syndicated newspaper column, syndicated public radio show and web site. In 2006, Long Island University awarded him an honorary doctorate as “one of the country's leading drug experts for the consumer.” .
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My doctor put me on lisinopril, and for 2 years everything was fine. I woke up one morning and had a hard time breathing. My son rushed me to the hospital. By the time I got there my tongue was sticking 4 inches out of my face. They had to do an emergency tracheotomy. I barely made it. Ever since, I’ve had problems breathing. I’ve got neuropathy. I acquired several problems from this drug. I owe the hospital $38,000. I’m trying to find a lawyer to help me with this. Somebody needs to be held accountable. Any advice? Thanks.

This class of drugs should have a BLACK BOX. The biggest hazard is that the severe reaction, angioedema, can occur after taking the lisinopril for years. I know. I was so afflicted. Live 2 miles from hospital. Rushed to the ER. IV infusion and steroids. 2 more hours, and I would have had a trach or death. Epi pen is no use in this reaction.

My blood pressure crept up to 160/95 and, at age 39, this alarmed my Doctor enough to prescribe me something. I am intolerant to alcohol, so I have never drunk. I hate smoke so I have never once smoked. And I am 6′ tall and 180lbs and have never been overweight – GO FIGURE that I would get high BP! ugh).

After trying “norvasc” and having bad side effects, he put me on Lisinopril 10mg. Knowing that I am sensitive to medications, I cut the pill in half, so I have been taking 5mg. My blood pressure is down to 105/65, and I feel great!! I guess I did not realize how bad I felt with high BP until I treated it and can look back and say ‘wow.’ It was affecting me greatly. It took about 3 days for the lisinopril to build up and start working. I check my BP twice daily. It was dropping slowly every day, but the third day was the day it finally came down to 105/65.

Anyway, I have had absolutely zero side effects on Lisinopril. I read all these bad reviews, and I know everyone responds differently, but this one is a winner for me. On top of it all, my insurance copay was $1.60. LOL. No complaints here. Thought I would share a GOOD experience, seeing as people usually come here only when they have a bad one.

After taking lisinopril for a number of years, I had an apparent “Bad reaction” on my way home from LA. I walked on the plane at Orange County airport, got up twice to let people seated inside of me to sit down. By the time we landed in Salt Lake 90 minutes later, I could not stand up and my legs refused to function. They had to get a couple of grunts to lift me out of the seat and onto a wheelchair. I was met a few minutes later by EMT’s at the airport who found that I had low BP and suggest a transport to the hospital. After evaluation at SL Regional, they couldn’t find a cause and were on the phone with the U of Utah hospital when my hand and arm function started to deteriorate. The U told Regional to get me up the hill. ER at the U ran a bunch of tests, hit me with insulin and installed a Shyley port to do an emergency dialysis in the ER. Long story short, blood test showed my potassium level to be in EXCESS on 9.8, the highest ever recorded at the U. So is lisinopril the culprit?


I had tingling sensation in upper lip. When closing my mouth the teeth had the sensation of being cushioned to the jaw bone. At the same time my right hand thumb had numb sensation. Will wait and see if it’s responsible for this sensation when I quit lisinopril.

My mum had an annoying frog in the the throat repeatedly over a year. She now has yearly scans for her lungs, and a ball has formed in both lungs. No frog now. She lost weight over a short period, is frail, and unable to take care of herself. The doctor said ‘we wont be doing that’ when asked to check her meds against her symptoms. It clearly says on the statin insert side affects: “breathing.” My doctor hasn’t given anything for relief or to make her comfortable.

The Health visitor remarked that she doesn’t look ill enough. But kidney failure, lung disease, emaciation, breathing difficulties and urination has her up in the middle of the night. Haven’t seen/heard from the health visitor in many months even though she said she will help me back to work with a care-giver on hand. I think it’s pathetic and will discuss going private. Her symptoms match with Type 2 diabetes, and she was much better before. Don’t take comfort from these statins and blood altering meds. Consider Homeopathy. I will. Take charge now!

The worst medicine ever put on the market , caused me pain dizzy all the time , headache, I start to faint ,did all the test in the world, I changed my dr finally , my new Dr took me off that horrible medicine lisinopril , thank god stopped fainting , Get off the market , It’s bad medicine 😟

My name is James. About a month ago I discovered my BP medicine linisopril has been trying to kill me the last 8-10 years. After 3 colonoscopies, 3 endoscopies, gallbladder scans, and etc. I was told to learn to live with it. I suffered acute abdominal pain for the last ten years. BP 250/15 and as low as 80/44. Small intestine angieodemea sucks. The town where I live not one medical person ever heard of angieodemea of the small intestines. Within 24-48 hrs of stopping BP medicine symptoms subsided. 30 days off linisopril, still no symptoms.

I think I am going to stop taking the lisinopril, 10 mg. I stay exhausted all the time and have chronic sinusitis and cough. Thought the fatigue, (extreme), was due to fibromyalgia. But started thinking it could be the lisinopril, as I’ve been on it for several years and have had this problem, but lately it is worse. My blood pressure was never that high to begin with. I am going to stop it and change my doctor.

Today is day #3 off of 2.5 mg. of Lisinopril. After 6 months of complying with my doctor to go on this medicine, I decided that I could no longer take the side effects. I was already overweight, but have gained an additional 10 pounds, some due to ingesting food of course, but also precipitated by lack of mobility.

I fell on concrete and whalloped my right knee on the concrete, also a re-injury, prior to the doctor prescribing this drug. Any aches and pains in my knees or feet were made worse by these drugs. I developed an arthritic band of sorts around my aches and pains along with a slight swelling. I was sore, I was stiff. Everything hurt, and I had all I could do to just go to work and come home. The tiredness I was experiencing ‘before’ the meds were made worse by the meds as now, as I said, all I could handle due to necessity, was to go to work, and that was all. Any errand or daily task was a chore for me.

Insomnia was exacerbated by the drug. My body lost its ability to adrenaline rush. My energy level, next to nil. I really missed my ability to sustain. I work long hours, on my feet and throw all I have into my job. It requires a lot of energy. I developed an intermittent cough that would often rear its ugly head even 12 hours upon being administered. I would drive home from work and start coughing and choking on my own throat and saliva so much, that I would have to pull over on the road and reach for a plastic bag, vomiting up phlegm. My throat would often feel as if it had been stabbed by scissors. My breathing would become slightly labored as soon as I would ingest my daily 2.5 mg. of this drug Lisinopril. I seemed to age rather quickly also, as my skin which has always had a tendency to be oily, became leathery like and dry. I developed grayish, deep circles under my eyes and my hair started to develop gray/white hairs in a snap.

The doctor informed me of the potential risks upon stopping, which is scary of course as well. I have all I can do to do more research and to calm myself down over this experience. I know I must make lifestyle changes, and I pray that I find the strength. I never fare well on meds. My being is very sensitive to any and all chemicals. Ps…I personally know someone who had a stroke, right in my plain view, even though they were on high blood pressure meds. WHAT does THAT TELL US???? Spooky world, spooky drugs! Be happy, be healthy, be well All! I shall rally on. Wish me luck!

I had been on Amlodipine 5mg but it made my ankles swell so much doctor put me on Lisinopril 10mg. I think he should have tried 5mg to begin. I took one pill and ended up in the ER with a swollen tongue and chest pains. I could hardly breathe. I was given an EKG and later I was told I could go home or stay overnight. I decided to go home but in the middle of the night I broke out in itchy red hives from head to toe. I thought it was from the sticky patches they put on your body for EKG but no. It ended up being from the Lisinopril.

Any lawsuits on taking lisinopril?

cardiology np started me on lisinopril 2.5mg, had a slight productive cough thought to be caused by sinus infection. Treated for sinus infection, cough has gotten worse affecting sleep. BP was not controlled by 2.5 so FP raised to 5 mg and cough especially at night has gotten worse. Will ask to be tried on something else.

I’ve been on 2 months. Have the cough, dry mouth, swollen feet and red , purple viens on ankles. Cancer survivor stage 4. Also have Afib. 15 yr survivor. Lisinopril is not good. Dr’s apt tues and getting off it.

The first day I took Lisinopril 12.5mgs my blood pressure dropped very low I got dizzy, passed out, had a stroke. Is it coincidence or all related to the Lisinopril?

10 years ago I was started on Lisinopril 20 mg (male 48 yrs old at the time, 220 lbs). which was then raised after 5 years to 40 mg. In that time my energy levels have tanked, and I have put on 100 lbs of weight. I have always been very athletic and full of energy. Now I am a lethargic blob. Last year I kept getting massive swelling in my lips. Like my lower lip only would suddenly swell to a huge size. Then next time the right or left side of the upper lip. I would take 2 or 3 Benedryl immediately, tried ice, etc. to get the swelling down.

I thought I was touching hot pepper oil somehow at the grocery store or maybe I was allergic to the plasticizer in the garden hose. I had no idea it was the Lisinopril! Thanks to this article, the mystery is solved.

My BP was not even that high. I am going to stop taking them starting today and see if my energy comes back at least. My quality of life is so bad with no energy and all this weight. I wonder what exactly the pills were preserving.

I have been on Lisinopril for about 4 mts 20 mg for about 4 mts nasty cough so I cut them in half still a cough. Plus sexual desire is pretty much nothing. About ready to toss them.

Well, Thank your the opportunity to tell my true experience with Lisinopril. First off, would talk to my doctor before stopping this med abruptly. I am not sure it would hurt you, but it always best to follow your doctors advice. But from I have experienced, I would say, get off of it as soon a possible, it is truly a dangerous drug and it should not be on the market. The risk are too great for your health.

My physician put be on this med for what she called high blood pressure. My blood pressure was 140.70. My age is 77, so according to some doctors that is not a bad blood pressure, but she wanted it down to 120 or below.

I was on it for almost year, but during that year I experienced anfio edema of the abdomen. My stomach and abdomen would swell, and I could not have a BM. So I would take a laxative about every 4 days. But going through this cycle I would have terrible diarrhea. It has continued to go on that way for about a year. It has been horrible, and my doctor, I know, even though she did not express it to me, thought it was all in my head.

But finally the worst happened. One morning I woke up feeling horrible. And after lunch I noticed my throat and tongue were becoming swollen. I became frightened and went the the ER. They recognized it right away as a side effect of Isinopril. I could hardly talk or swallow.

The nurse looked at me and this is a medical emergency. So they started an IV on me, and gave me meds for nausea, also a steroid, and finally an epinephrine through an IV. But the epinephrine caused exceeding great pain my the middle of my chest. I screamed out at the nurse, I am having a heart attack. She told me to take deep breaths, and she said it will pass.

It did, and after I fell asleep. They wanted me to stay in the hospital but I am single and had a dog at home in the house that had probably run of food water. I told them I had to go home, so they let me. My throat and tongue had gone almost down. The next morning it was all down and they had taken me off of Lisinopril. and put me on another blood pressure med.

Oh yes, I had also developed a terrible cough during the year I took it. My doctor wanted to take me off of it, because of the cough, but I told her know no, that it kept my blood pressure down, and I would stay on it, I did not of the other side effects.

Because this med stays in your system ever after you stop it, the next day I could not poop and had a terrible time peeing. I ended up going to the ER because I could not pee. They catheterized me and only got out 250cc. But when I turned on my side and they went to discharge me back to home, 900 cc had come. They also drew my blood, and did a CT of the abdomen.

Nothing was wrong with my blood or my kidneys, or anything in my abdomen, at least that is what they told me so I went home. I went home, and I knew i had to have a BM so I took MOM. It did make me have a BM but not easily, after that I had terrible diarrhea. I had diarrhea. that continued, and I became nauseated. That went on all day, The next morning I woke up and I could not eat or drink I was so sick and still having diarrhea.

I felt myself passing out, so I quickly threw my clothes on and drove back to the ER and told them I was terribly dehydrated. . They started an IV on me and gave medicine for nausea, drew my blood, and the results came back that I was low on sodium and chloride. After I laid there in the ER for a long time, on my left side my arm and leg began to go numb also my face and neck.

I hollered out for somebody to come help me. Finally, the RN did come back in but were really not concerned about me. But I had started started shaking violently, and I vomited and peed on myself. He got a doctor finally and he was the doctor that saw me when my mouth and neck had swollen.

They gave me Ativan and something for nausea which stopped the vomiting and my anxiety attack, the doctor said was happening to me and they admitted me into the hospital. The next day cardiac specialist come into my room, and told me I had a heart attack when they gave me epeneferine and told me he would like to do an arteriogram on me.

I said OK, so they took to the room for the exam after giving me something to calm me, and the next thing I knew I was back in the room in which I had been admitted. I spent the night and the next day he came into the room, and told me that he found out that the right coronary artery was 69% blocked, so he put in two stents.

Almost the last thing he told me was, “Well, Ms……..B you have been through quite a hard ordeal, but if it had not been for that Lisinopril and the angio edema in your throat, this blockage would not have been discovered and you could have had a fatal heart attack.”

That is the only good thing I can say about taking lisinopril, but I would say, get off it it, and do not go through what I did. Truly the last four days of my life have been hell, but thank God, as a Christian, God was watching over me and brought me through it all. Of course, the Cardiac doctor has put me on Plavix and a baby aspirin for three months and I have a follow up appointment with him.

I am home now, and so thankful for God’s care for me through this horrible experience, and that I am alive, and want to live for him in this wicked world. I was very weak when I got home, but tonight after eating a good supper, and my appetite has come back in full force, and to top it off I do not have high blood pressure at all any more.

Thank you for reading my true story and my experience with lisinopril.

Hi Kay! What have you done to lower your blood pressure? Can you share your successful tips with the rest of us?


I’ve been on Lisinopril 40 mg. for my BP and developed a cough a year ago. My doctor tells me how well my BP is and hates to change my meds. My husband informed me that since this all started I’ve become a blob. Reading all these posts has made me decide it’s time to take a stand on this medication and get it banned from being prescribed to people.

I am also encountering the same symptoms as described by the other past and previous users of Lisinopril and am still being prescribed this medication for high blood pressure.

I have been taking Lisinopril now since 2003 ~ 15 Years. I have severe lower back pain, and associated it with a toxic dose of Arsenic I received from a well on a property I was renting in the country. I got shingles as well, with a full body rash, and that went away after no longer drinking the well water. But I was ingested 4 times over the legal amount and suffered. Now after reading these testimonials I WILL NEVER TAKE ANOTHER ONE OF THESE PILLS!!!

I couldn’t believe it is made from snake venom. Wow! What a shock! I don’t want to have any of the dreadful cases that have been printed here so NO MORE FOR ME. I’ll get an alternative natural method to keep the BP in check! Thanks to everyone who has INFORMED us of the terrible things they had to go through (so very sorry to hear of so much pain many endured. Doctors don’t have a clue most of the time. They just give you ANOTHER PILL and send you HOME). I still have severe back pain but ANXIOUS to see if this will STOP when am o longer on this poison (literally)!!

Who said Lisinopril was made from Snake venom?


I was on hydrochlorothiazide for a time and have recently been on lisinopril 20-25mg. I thought I was about to die until I read this post. I have felt like I can’t do anything because I can’t catch my breath. My muscles are sore when I walk. I get so dizzy especially if I been crouching down. I throw up everyday without fail, usually morning or evening. Most of the time am just heaving and generally feeling crap. I have been getting lower back pain and no energy even to clean up my little apartment. In my head I’ve been thinking it’s either stress from work, menopause or this is it. It’s all over. Maybe it’s my time to go. It’s really scary. I’m a 49 year-old woman with no previous medical concerns, only high bp and low potassium.

Last night I didn’t take it so I will see what happens. I’m getting regular blood work done tomorrow so I’ll see if anything comes up in that.

I’m so glad I found this site. You guys really put my mind to rest a little.

I have been on Lisinopril for 1 year, because of high blood pressure. I am 58 years old today. My story: about 2 years ago, I was under extreme stress due to aging parents, large family, fighting, guardianship, etc. From all this, I developed high blood pressure. I went to my Doctor, and he prescribed lisinopril. BEFORE I started taking this, my creatintine was .75, very good. My kidneys were 74, very good. Mind you, no doctor told me to come in for routine blood work. This June, 2018, I got Vertigo and went to the ER. They did blood work, and said “Your kidney numbers are high, but that’s probably due to de-hydration. Since then, I have had 3 blood panels done. My creatintine is now 1.45, and my kidney number is 41. My doctor’s tell me, Oh, that could be from the lisinopril. But yet, they tell me on the other hand, it could be protecting my kidneys. Bottom line, they don’t have a clue about this damn drug! They are telling me 2 things! Now, with me begging, they agreed to put in an order for an ultrasound of my kidneys, since I got as low as 41. I am so angry! And scared! My kidneys are bad probably because of the lisinopril. I combed through all my blood tests results, and they started getting bad AFTER lisinopril. ~

I been taking lisinopril for 2weeks and I get dizziness and faint feelings, I’m going to tell my Doctor I’m going to stop taking it and find natural solutons

They started me on 20mg once a day which made me dizzy. Lowered it to 10mg once a day, still dizzy. Finally 5mg twice a day, I am no longer dizzy, and my blood pressure is under control. I take my BP regularly at home and at rest it is usually around 120/80. I would like to stop taking it so I am starting to exercise again.

I’ve been on Lisinopril for 4 days. I’m supposed to take one 10 mg tablet a day. I take a pill at bedtime and I wake up a little light headed but that’s not the worst of it. I’ve been short of breathe everyday. I had trouble changing the sheets on my bed yesterday. I had to stop and rest and catch my breath. Last night I didn’t take my pill and this morning I woke up fine. I’d like to suggest an alternative medication to my doctor. Any suggestions? I’m slowly changing my diet to a more plant-based diet.

In reading on the side effects of lisinopril, I notice a listing of sexual difficulties as one of the side effects. Since I have been taking this medication (2-3 years now) I have experienced a huge drop in sexual arrousal and establishing an erection is almost non-exiistance. Please advise, I truly like being married, but this issue is causing difficulty

My blood pressure was high 160’s/110’s so my doctor put me on lisinopril and I had to increase to 40 mg to lower my blood pressure. It did perfect on lowering my blood pressure but the side effects are terrible and I am stopping taking today. I have started coughing, terrible fatigue (barely can get through the day), and my wife has a complex because it completely zapped my sex drive.

Was put on 10mg lisinopril in Jan 2018 for bp of 160\100. I’m 50. The first couple of days were fine: only a little cough but bp was down to 120\80, so I thought everything was fine. Two weeks later, developed severe fatigue along with heart palpitations (I’ve run track and cross country for 30 years and never had heart issues). Two days after those symptoms I started to get abdominal pain along with severe dizziness (vertigo type–the whole room was spinning). I stopped taking it against my doctor’s wishes. Blood pressure went back up even higher 165/115 but I refused other meds due to all of them having potentially bad side effects. Decided to become a vegetarian. It’s been a struggle but I’m starting to feel better and bp is avg 140/90. Some days it gets as low as 120/80, and that’s natural. If you can do it naturally don’t take the pharma drugs. They may eventually kill you probably sooner than later.

My husband has been on lisinopril since 2011 following a heart attack. In 2015 he went for a routine exam and was told he was heading towards kidney failure and the dr. asked him how much alcohol he drank. Dr. basically accused him of being an alcoholic. He had low serum sodium amongst a host of other disorders including anemia, B-12, folic acid anemia. I suggested to the dr. to take him off the HCTZ, to which the dr. responded, “that is an excellent idea”.

In 2015, he also suffered sudden hearing loss in his left ear and the doctor misdiagnosed him and treated him for allergies. Ended up seeing an ENT, had brain scans, but there is no cure because he should have been sent to the hospital. It can be cured if caught within the first 72 hours. Fast forward to 2017, now under the care of a neurologist for neuropathy from unknown cause. Low serum sodium, anemia, neuropathy.

My husband went through 18 months of blood testing and scans. Now pops up a lung nodule and enlarged lymph glands. He needed a biopsy for lung cancer which meant he needed medical clearance. I kept bringing up “he has low serum sodium” and every doctor said the same thing. “looks like he has lung cancer”. Because he was having surgery he was sent to a nephrologist for clearance. The first thing the doctor said to us was “stop taking lisinopril”. That was on a Friday. The next Tuesday his sodium serum levels were back to normal. His cough (we thought was from the lung cancer) is gone. His nightmares (we thought from stress) are gone. His energy is coming back.

We are still waiting for the biopsy results 8 days later. Now, he is starting to hear noises in his deaf ear? Did lisinopril cause the deafness? Is lisinopril causing neurological disorders? I feel this drug should be taken off the market. Not one doctor told us about any of these side affects. Took two and half years of suffering before we heard the words “stop taking lisinopril”.

I went to the ER because my great toe was inflamed. I was diagnosed with gout and I read about hydrothizides HTZ and came off and was given a Rx . what can I do to not have it come back. My uric acid was elevated…

This article is written in a very unsatisfactory way: Lisinopril and ACE inhibitor are talked about as if interchangeable, with no discussion of whether other ACE inhibitors such as monopril have the same hazardous effects. If Lisinopril is the only drug in the class of ACE inhibitors to beware of, then say so. If not, then say that: “Lisinopril and the other ACE inhibitors….” can lead to ….the symptoms and effects you describe.

About 5 years ago, my GP put me on lisinopril for mild high BP. I did have the coughing, and it made me a little “loopy” (light-headed at times), but otherwise seemed to be working. However, a few weeks in, I had a severe reaction after taking a single dose of aspirin (at a different time than the daily lisinopril). I had severe angioedema with my face, eyes and lips all swelling up. They pumped me full of Benadryl, and I stopped taking the lisinopril. The angioedema went down, but never completely went away.

Now, many of the foods that I’ve had sensitivities to since I was a kid (although Western medicine still claims I’m not allergic to), are now intolerable. When I eat these foods, and now a host of new foods that I had no problems with in the past, I puff up like a blowfish after a few hours; my ears ring way more than normal; and I feel like crap, lasting over a day. My allergist has now put me on a heavy dose of Zyrtec to clamp down the histamine response, but it only partially helps.

Whatever this interaction between the snake-venom lisinopril and aspirin, it has permanently changed my physiology, and the doctors don’t seem to care to know why – they only want to mask the symptoms. This has virtually ruined my life because there are so few foods I can eat now without causing this, that I’m constantly fighting the symptoms, which also seem to affect my cognitive abilities slightly (maybe due to angioedema in my brain?). Has anyone else had an interaction like this or similar symptoms even long after stopping the lisinopril? Thx.

This lisinopril a nightmare medication. I could not find out why my lips mouth and airway were closing. Thank goodness for online sharing like this. My sister had the same reactions.

I started taking linospril in march 2016. After taking this drug for 3 to 4 months I notice large pugle marks on my skin plus a severe cough & confusion, felt faint at times because I had to pull the car beside the road. I ask the doctor what was going on, and he hunched in his shoulders. He finally placed me on Losarartan 25mg which my new doctor took me off & and placed me on Norvac. Lisonopril caused me to have asthma and a mild stroke. I never was sick before I took this drug. I had the flu in 1968 & that is the only time. I am still trying to get better.

Are Lisinopril and Amlodipine and Isosorbide in the same category, “related” ?
I have been on Amlodipine and Isosorbide for about 10 years, no problems

About 4 weeks ago, I started to have the following symptoms:Night sweats, , unstable walking,
Shortness of breath.

This on top of what I had noticed earlier;
Unproductive coughing, Pain in joints and muscles cramps, hair loss, severe dry eyes. fullness in my belly, before i had anything to eat.
Had to take tums now and then.

Very tired and could sleep for 12 hours if I wanted, but I tried not to.
I am very careful with taking meds, but this is not funny.
I am starting to taper off the prescription meds.

Last week I had all the blood test done, a chest Xray and every thing came out “perfect”

I have been under severe stress for the past 2 years, when my son was diagnosed with Mucosal Melanoma ( it showed up on the liver and pancreas, during surgery for a ruptured appendix.

By the way, this is a new sort of cancer.

My son was a picture of health. went to the Health club and was able to lift 250 lbs of barbells and would run 5 miles on the tread mill.

Because he was so healthy, he lived for 15 month and had so many other things showing up.

The age group is now males in their 20’s and up to their 50″s most cases, I have heard of, live only 5 month.

My son, had no symptoms at all,until he had pain in his belly and he had the the ruptured appendix,

May be through this side, other people can be saved by having regular check ups.

Has anyone had a TiA of recent? I missed a week of news. Im taking both the meds of Lisinopril n hctz. Im kinda of scared now. No swelling, however the dry cough is back, along with nose dryness.

Why put your body to risk with dangerous drugs when all that is needed to keep healthy is 2 quarts water and a fountain syringe used twice a week. Positively no side effects with this usage.

I had no doubts. The coughing started immediately after beginning Lisinopril. It kept me awake and made my ribs ache.

I have had no problem after 6 yrs of using it.

My husband was on 40 mg for a couple of years. When the kidney doctor took him off Lisinopril, his creative count started coming down. But the damage was done and he continues to see the kidney specialist.

My Dr. put me on Lisinopril several years ago to bring my blood pressure down slightly, prior to major surgery. It worked but, as I continued to take Lisinopril post-op,i began experiencing frequent vivid nightmares.

I looked up Lisinopril and found that it was originally derived from “snake venom”,so I discontinued it and the nightmares went away!

I think that it’s best to use non-allopathic (non-prescription) methods to control your blood pressure rather than prescription drugs, if possible.

Been on Lisinopril 10mg/day for 5 months, still on it post CABG-3. Got the cough, but it’s more of a nuisance than a threat, so far at least.

My husband died from lisinopril and another blood pressure med – the combination.
At the same time he was taking these meds which lowered his pulse to dangerous levels, he developed a large kidney stone (not saying it was because of these meds) and went to the hospital three times (every two weeks) to be put “under” to “blast” the kidney stone). Each time he was seen by the same doctor but different anthesiologists which would comment on his pulse and one even said… “Gee, your pulse is so low -dangerously”- and we’d ask him if we shouldn’t have it done, but they said if he died, they would bring him back (and laughed).

I believe the combination of the blood pressure drugs and then the treatment for the kidney stone resulted in my husband’s death a few weeks after the third treatment. None of these doctors called or sent a sympathy card, but they all got a lot of money treating him. BTW: My husband was a swimmer and two days before he died, he was swimming 40 laps in an olympic size pool 4 times a week. We had an autopsy and the pathologist found nothing and stated it very well had to be the combination of blood pressure meds. The lawyers all agreed that for every expert I could hire for a lawsuit the doctor’s insurance companies would be able to hire ten experts and also keep this case going for years and years – and I would lose eventually.
There you go. The end.

Lisinopril is made from snake venom–the Brazilian poisonous snake, but not enough to kill a human outright. The side effects of this drug are also signs of snake venom toxicity.
Snake venom dumbs down, depresses the entire body functions, including the blood pressure.

People need to know what they are ingesting—the ingredients in food, as well as the ingredients in drugs.
Processed foods have labels listing ingredients. why don’t drugs ?

The Medical and Pharmaceutical industries don’t want to cure anything, they just want to manage it, theirs more money in it that way. I see people in grocery stores all the time with a lot of health problems, and just by looking into their shopping carts I can see exactly what’s wrong with them, nothing but sodas, junk and processed foods loaded with chemicals and sugar.

I’ve been experiencing a repeated occurrence of boils. Im beginning to attribute the boils to the blood pressure meds. Ive been ambivalent about taking lisinopril, so sometimes I don’t take them, but when feeling guilty about not being extremely mindful of my diet, I’ll take my pills, which includes 40 my of lisinopril and 10mg of norvasc. Within several days, I’ll begin to experience the onset of a boil in various locations around my body. They are excruciating and have begun making me depressed. I’m pretty sure it’s the blood pressure pills. I don’t want to go to my doctor, because he’s going to insist I continue to take them. We’ve been through this several times. I just want off of the meds. Help! Please.

I too was on Atenelol, and was told it was discontinued by the mfg, so started me on lisinopril then my BP was going up, so she doubled Lisinopril to 40 and that made it worse. started on 20mg with water pill and it is way down. All the while I have been battling bronchitis with alot of phelm, so now I wonder if lisinopril is causing that too. taking brochidialator just to stop the cough. It probably isn’t the best remedy for BP, Sorry not to be of any help. ready to go to a cardiologist.

I have been on lisinopril for several years, after undergoing open heart surgery I am taking 2 -10 mgs twice a day or a total of 40mg a day. I went to a new pharmacy to fill my prescription about 6 weeks ago and was given a different generic by Lupin. It’s a pink pill and I used to have. White octagon shape. The past few weeks I am exhausted, dizzy, unsure of my stepping and in general feeling terrible. Awaken at night in a sweat. I am 85, live alone and I have become very depressed. I need to find out if lisinopril is causing this.

I have been on Lisinopril for over 8 years. I have never had a problem until one week ago. Got up to go to work and my face, tongue, throat was closing. Went to the ER and they side it was a side effect of Lisinopril that caused angioedema. Went to my family doctor and he changed my medication to Chlorthalidone. By Wednesday I was back to the ER same problem but worst and put in ICU until everything went down. If you are taking this I would stop. Both times it started as if I was getting a fever buster on my upper lip and both times I woke up from sleeping with the full effects of angioedema. What if I did wake up I could of stop breathing altogether. I was lucky, but someone might not be.

A Heart Doctor put me on this DRUG and it almost crippled me. I could not get up and had severe weakness in my legs. Fell several times and as dizzy a lot. My doctor did tests on me and had to prescribe very high doses of vitamin-D3 and high doses of Calcium.
That is when I Googled the drug and found that was causing it. This drug is a Calcium Blocker. I threw the CRAP away right then. I have gotten some of my strength back but it is a very slow process. I do NOT take any drugs now and will Not do so no matter what the Doctors say. It never did make my blood pressure down anyway. I wish I knew of a NATURAL way of lowering the blood pressure and getting my strength back.

Donald — search this site for natural ways to lower blood pressure — hibiscus tea, theanine, stevia, beet juice, etc.

I have had a constant itch also there is unexplained yellow bruises on my body coul it be Lisinopril doing this.

I have been on Lisinopril for at least 6 mos but recently I’m experiencing tooth loss on my lower jaw. I did some research and discovered that it can cause tooth loss. I’ve not discussed this with my doctor as he would probably dismiss it as nonsense.

I am not prone to exageration or hyperbole regarding health matters. I keep a clear head and look for sound solutions. However, lisinopril was a nightmare.

I was getting sick and weak. My doctor tested me for everything, lyme disease, HIV, lupus, Parkinsons, but could find no explanation for my severe fatigue, dizziness,extreme nauseau, depression, a terrible relentless metallic taste in my mouth. She decided it must be fibromyalgia and prescribed Cymbalta. The Cymbalta helped a little bit with the fatigue, but that was it. And I really didn’t want another pill.

I ended up in the ER. I couldn’t take it anymore. My body temperature was dropping. I couldn’t eat a thing. I was able to get a protein shake down but nothing else. I could barely crawl out of bed. I felt like I was dying. That’s no joke and no exageration. I thought that I had to have some kind of serious viral infection. The ER doctor tested me for EVERYTHING… blood test, urine test, cat scans, heart monitors. When the ER doctor told me that I was “healthy”, I wanted to cry. How could a “healthy” person feel so deathly ill??? He recommended seeing a neurologist. He thought I might be in the early stages of MS.

I came home and looked at my pills. I remembered that when the my primary physician first prescribed lisinopril for my high blood pressure a few months back she had to adjust the dosage because it made me dizzy. Something told me to get off of it. I did.

That was 3 days ago. I’m not 100 percent yet. There are still some residual symptoms but I am SO MUCH BETTER. The symptoms are slowing easing up. That horrible metallic taste in my mouth is gone. I can eat. I can get out of bed. I have a life again.

That lisinopril was poisoning me. I will take my chances with no blood pressure medicine before I’d ever take that again. It was a nightmare.

KIM, I have been taking Lisinopril for 4 years and just came down with the same issues. I was battling a bacterial infection in my prostate and once got better, still have very very similar issues you describe. Heavy head, dizziness, fatigue. I have been tested and tested and they are saying I need to see a rheumatologist now for MCTD or Lupus.

Passed out yesterday goin down the road…Went to the Doc. Today an she took me off it..I could tell she thought it was the Lisinopril that caused it….I allmost got killed….

I’ve been on lisinopril a little over a year and in the last couple of weeks I’ve been experience muscle craps , joint paint swelling around my neck, knees, ankles and hands/ feet. I’ve also have pain in my jaw that’s so severe that I can’t even eat and barely can talk normal. I’ve diarrhea, nausea, light head, numbing of my face, constant tingling in feet and hands,blurry vision, quick heart beat (which slows to a slow weak heart beat), back pain, sore throat, bloated stomach, dry patchy rash, sensitive gums, nightmares, feeling like the room is still spinning, thinning hair, congestion, weakness, stomach cramps, and early aches constantly. I’m 38 yes old and has had hypertension ever sense I was 9 years old. I’ve never been over weight. I can’t understand why this is the only medicine that has made my life a living hell. I went to the ER and the doctor was clueless about my situation but the nurse told me that I was having bales palsy do to lisinopril. I was told to stop taking it. I’m so afraid because having cheat pain and pain in my right arm. I feel like I’m having a stroke or a heart attack. I can’t deal. Dr’s should not prescribe medication that they are not familiar with all the pros and cons.

I am taking lisinropril and have dreadful experiences since started taking it. Just to many issues as stomach like in a vise, chest pain sometimes, spacy, palputations, taking chlorthalidone with it just a bit for water retention, never got bloated before – getting so bloated my body was tight and can’t do any more of these drugs! This whole thing is turning me inside out. I am going to stop it – was so ill i couldn’t go to dr the other day and leary about going back there. Am trying not to be upset and taking more magnesium to calm my heart beating out of my chest. And much better than a few days ago. Make sure if you are having effects that you get your dr to pay attention! Guess i need to go to dr with a flashing neon sign to be mindful of me!

Any medication can effect different people different ways. One persons “miracle drug” can be anothers nightmare or even fatal. It is wise to be alert for serious side effects , especially when first starting any drug or off the shelf supplement. When you have a serious condition like high blood pressure, the worst thing you can do is try to ignore it. The public is caught between a rock and a hard place. Go to 10 different doctors for high blood pressure and you could easily get 10 different prescriptions. The pharmacies make the problem even worse by buying whatever generic is cheapest. What can you do ? I lost any trust in the entire industry and any connected with it many years ago. When you have no choice, you do your homework and roll the dice.

Reading this because of side effects of Lisinopril. Couldn’t help but notice how many “rare” cases of terrible side effects are listed here. Maybe they are not as “rare” as patients are led to believe.

I have been taking Lisinopril for about 10 years. During that time I have experienced no side effects what-so-ever. I do have mild kidney disease probably caused by type 2 diabetes, but my numbers are constant and thus not getting any worse.

Has anyone experienced Nightmares? Myself and two others on lisinopril have this occur when the pharmacy switches to a different generic medication vendor. I can only take lisinopril from Cintron.

Sometimes I wonder if it’s the inactive or additive ingredients they mix into a generic medication, and not the lisinopril active ingredient. Have also heard that certain generic forms of Lasix (a diuretic) work better than others depending on who manufacturer is.

We share a name, Patty, as well as having nightmares on Lisinopril. I, too, have bad dreams from Lisinopril, and also have had headaches for over 2 years. Stopped the Lisinopril to see if it was causing the headaches, and while unfortunately those have continued I did make the happy and inadvertent discovery that my normal dreams have returned. I had not realized how important it is for me to be able to sleep without nightmares. This is a huge improvement in my quality of life. I found your post when seeking information on possible alternative drugs to treat my hypertension. I’ve made a list of non-drug ideas as well, like losing weight. Drug-free would of course be best, if the BP can be improved.

I was put on lisinopril 5mg a day for coronary artery disease and hypertension…my primary doctor felt my pressure was still way to high so he increased the dosage to 20 and added a diuretic to it in the same pill – Lisinopril and Hydrochlorothiazide combo. The first day I took this I had blacked out completely and woke up on the floor. When trying to get up and move again I made about 3 steps before blacking out again. It nearly killed me by lowering my pressure to 60/40 and barely 25 bpm when I got to the ER. As soon as I was given an oxygen mask I began to stabilize immediately luckily, and now they expect me to take 10 mg a day lolol. I have changed my lifestyle and diet completely and feel a million times better. Also my pressure seems to be stabilizing on its own naturally now. I believe this is not a good drug and that it can kill you if you’re not vigilant about your pressure and only take low doses when you really need it. I will take a 5mg tablet only when my pressure is high and even then I get dizzy from time to time and feel weird on it. Nothing compares to healthy eating and lifestyle.

Monitor your salt levels when taking Hydrochlorothiazide as it can wash out too much sodium and possibly potassium salts causing a dangerous health situation.

I have been on Lisinopril for the last 10 years, on and off, and with the different brands that have taken over the drug throughout the years. Let me tell you something, the brand and manufacturer make a deference. I had the cough, and trouble with digestion in my esophagus, and even nightmares. The worst brand was LUPIN. That stuff was horrible. However the newest brand of the drug, SANDO, works much better than all the brands before it. While the side effects aren’t easy to handle, let me tell you that in my case, some of them were temporary. The cough was temporary; the headaches were too and went away with the SANDO brand. I needed to give my body time to adjust. It was whenever I stopped taking the medication that I had chest tightness and couldn’t breath, because my blood pressure was going back up. This medication has been proven to improve heart function as well as blood pressure. I have had periods of time without it, and know the changes that come with it.

It’s not for everyone, but give it a chance to work. And please, drink lots of water. Keep in mind that the water will go straight through you if you’re not eating healthy fruits. Look up fruits and other food sources that hold onto water in your system; this is also good idea for the bowels and skin appearance. You definitely should not drink alcohol with it. There is one benefit to taking this drug, in my case it helps me to lose weight and control hunger if I take it consistently. If I skip it too many days in a row, I feel okay for about the first week off of it – but remember, it’s still built up in the system; so don’t think you’ll be fine without taking your blood pressure medication. After that first week, maybe by the second week, you’ll go back to getting angry faster, because your blood pressure will go back up to high levels. And, you may start eating too much. Stay away from coffee, and sodas on this product, because it can give you acid reflux. Again, I’ve been taking this drug on and off for 10 years. I know what I am talking about, however symptoms are different for everyone.

My significant other had been on Lisinopril for many years without any reactions. On Jan 3 of this year he woke up not feeling well. Within a short time his tongue started to swell and he was having trouble breathing. He looked in the mirror and his neck was swelling by the minute. Thankfully my son was home and drove him to the ER. He was placed on a respirator and the doctor stated he had about 2 min of life left. He was in ICU for 5 days. They almost had to do a trach. We know that this is a rare side effect but we would not suggest anyone ever take that chance. He was lucky but I wonder how many others weren’t!!

It’s only 3 days 10 mg of this medicine and it lowered the pressure to normal but holy. I feel worse now then I did with the high bp. I’m weak, chest tightness and shortness of breath..I’m done calling doctor, the rest are going in the garbage..I’m really going to work on my diet so I don’t need these pills. A healthy lifestyle is the real answer not drugs.

I am literally in the hospital now with the face swelling, and thinking back I also had the terrible stomach pain which I kept being told was severe gas.

All the time, I thought it was food allergies or drug interactions. NOW, after reading some posts, I realized this was all from the Lisopril. Thank God throat wasn’t affected to the same extent.

I’d been on Lisinopril recently for the last 4 yrs. reading prev testimonies, i now realize i had been experiencing side effects from the very beginning. starting with the tingling and sharp stabbing pain through out my entire body. I have lost my hair and the dry cough was so severe at times, my ribs were sore.

3 wks ago, I woke up with a swollen tongue. my new dr. immediately took me off this med. i now take Metotprolol Succinate Er 25mg and because the lisinopril also had a combo diuretic, i also take Hydrochlorothiazide 12.5mg. the diuretic doesn’t seem to be working because i wake up every morning with tight swollen hands. i will contact my dr. and inform him because i didn’t have those symptoms previously.

I’ve been taking combo 12.5/lisinopril/HTCZ water pill for the last ten years. For several years all was normal, as far as I could tell. The last couple years, I’ve had a chronic cough that is horrid at bedtime. I thought it was just a bad cold, but now I’m reading all these stories of people with similar symptoms, and my symptoms are getting worse, like shortness of breath and Nausea.

My stomach does not want to shrink no matter how much I work out. When the congestion is bad, I’ve found mucinex to allow me to breathe. Also, drinking lots of water reduces the sodium count to relieve the pressure in my lungs. Muscle exercises also allow for absorbing blood sugar, and to lower the count.

I have had a headache for three months it just started all at once one day and have it 24 /7 . I take 10 mg lisinopril have taken this for 5 years .my blood pressure has dropped to low levels in the last months 100/49 some days feel terible . Have every kind of test cat scan, MRI, all sorts of blood test. I was glad to here some of these stories maybe it is the Lisinopril.

I also have CKD stage 2 kidney disease/high blood pressure/heart disease/diabetes and I take two drugs. I don’t taking metformin and lisinopril because both can do serious to my health.

I read most of these comments but no one mentioned wheezing. I’ve been taking Lisinopril for about 3 years, and I wheeze. Never have had asthma or wheezing in my life, I am 70. Also I get very drowsy whenever I sit down, and in general have begun to not feel all that well. I am fatigued. Don’t have a cough, but this crazy wheezing that I can hear, especially when going to sleep. Before this drug I was on Amlodipine, developed a strange intolerable odor that no one else could smell, but was in my olfactory system. So was changed to Nisoldipine – same thing! I am going to make an appt. with a Naturopath.

My mother just started taking Lisinopril 2 months ago. Since starting, she has to go to the restroom 4-5 times a night. About 3-4 times now she has had very bad reactions where she is feeling nauseous, has tremors, has the chills and fever, is itchy all over, and can’t sleep all night. She feels so terrible, she says it feels like she’s in hell. I’m glad she is not going crazy and now we know it’s a side effect of the medication.

I also read that Red Zinger Tea can cause problems similar to Lisinopril

Get off from it. I was having dizzy spells for several months. I was on this drug for 15 months. It almost cost me my life from angioedema. It is rare this happens but I would not chance it if you are having dizzy spells. My dizzy spells were “light” for lack of a better word. I had to be flown by helicopter to larger hospital. That is how serious this was.

While on vacation in Texas I woke one morning feeling quite full as if I had just finished a big meal. It was uncomfortable but not painful. As the day went on it worsened and was extremely painful. Finally my husband insisted we go to the ER. They took me in immediately and did a CT scan. They diagnosed the small intestinal blockage immediately and started pain meds and an NG tube to empty my stomach.

I was admitted into the hospital and they told me it would resolve itself or they would need to do surgery. The next day’s x-ray showed that it was clear. I had been taking Lisinopril for at least 5 years with no noticeable side affects but during my stay (3 days) I was not allowed anything and eventually liquid. No Lisinopril. I was fine the next day. They told me I would need to follow up when I returned home. Luckily I live close to the Mayo Clinic in Rochester and at my appt. the Dr. reviewed scans from the hospital and did another CAT scan that day. During the appt. he diagnosed Lisinopril based on the type of symptoms I had. Not taking them in the hospital is what resolved the problem. I’ll be looking for an alternative blood pressure pill going forward!

I don’t like lisinopril for my high blood pressure. I been on this a long time. I need to get off this drug today but my doctor didn’t say anything about how bad this drug is. Should I stop taking it or get another doctor?

My already fine thin hair began thinning more when I started taking Lisinopril. I also passed out recently at a conference with no prior dizziness nor any other symptoms. I was taken to ER where they said I must have had a dip in BP. I had not connected any of this with the medication until now reading your news. I had previously been on HCTZ for years with no noticeable problems but began having low sodium so was changed to Lisinopril. I just had my prescription refilled but began having doubts. I’m 73 and feel fine and happyy otherwise. P W

I love the doc who gave me lisinopril, but I had Horrible heart paplitations. Try another doctor, don’t put yourself in danger changing with out a docs help.

Renee I have taken Losartan, Propanolol and am now taking Lisinoprol. I’ve experienced body tingles, sensations of pins & needles, a constant headache & insomnia to boot! I’ve been on Atenelol for high blood pressure for 10 years & never had any side effects! The meds mentioned were added due to my BP increasing! Dr, said these meds have the least side effects! Don’t know what to do anymore!

On December 15, I had to be taken to the ER due to really bad stomach pains. The pains I felt was worse than labor pains, it felt like someone was stomping on my intestines with high heel shoes on. Once admitted, the doctors ran all of the test from colonoscopy upper GI, and different blood test. Everything the doctors was looking for came back negative. While in the hospital they kept giving me my blood pressure med, lisinopril. My lips became swollen while I was there and I was told it was because of the test I had done earlier. I replied no something is not right, but they continued to say I was ok, it’s because of the test.

I suffered in pain for a week and 2 1/2 days while laying in the hospital. The Doctors could not find or figure out was going on and said we feel like it would be safe to send you home. They then released me from the hospital with instructions, a 2 week follow up appointment and another colonoscopy and also with an added blood pressure pill to go with the lisinopril. Once at home I continued taking my blood pressure pills according to Doctors directions and the pain, vomiting, diarrhea, the horrible coughing, continued. I began having chest pains and shortness of breath, I thought it was because I was trying to do too much to fast.

On January 17 my upper lip started to swell and later that night it got worse, the next day I woke up I looked horrible; my face, upper lip and neck was swollen even more. I returned to the ER that’s when the ER Doctor said I was having an allergic reaction to the lisinopril, they began to give me steroids and other meds to stop what was going on and to keep my throat from swelling up as well. They then released me with a prescription for a 3 day steroid fix. I thank God he kept me because I could have died. Feeling safe enough to send me home almost cost my life.

I have taken Lisinopril for 4 years after my BP was found to be high (155/90) at my checkup. It was a stressful time in my life and that may have contributed to the high BP, but the doctor said that I would need to be on BP meds for life.

The symptoms came on quickly (dry cough) and then continued to compound. Muscle cramps, dizziness, etc. My BP did go down to normal but the medication altered other parts of my life. I always felt either dizzy or high (not in a good way!). Sometimes I would be at lunch with clients and feared that I would pass out at the table. I also started to get mild anxiety attacks – probably from fearing that I’d pass out or need medical attention in front of clients or family.

Five months ago I started cutting my dose in 1/2 – went from two pills a day to one. In addition, I started exercising regularly and lost over 10 lbs. Even with this, I still had days where I just didn’t feel right. So I started to do research on natural HBP remedies. I started taking Cayenne Pepper capsules and garlic supplements. Also cut out all gluten (bread, pasta), soda, beer (ouch, I LOVE beer), sugar and other crap. Also went from 1 pill a day to a 1/2 pill per day.

My prescription ran out a few days ago and I did not have it refilled. My current BP averages around 134/84. I can live with this. The last 5 days have been awesome – no dizziness, feeling out of it, etc. I feel like a normal person again. At 53 years of age I am looking forward to driving, skiing, biking, hiking and more importantly spending time with family (wife, kids and grandchildren) in a normal state of being.

I think that obtaining this nirvana of 120/80 is insanity. Some of us run a little bit “hotter” than others; we may not live as long, but as long as our BP can be maintained at a reasonable level then we may live as well as others.

My advice to others: unless your BP is so high that you are in imminent danger then I urge you to seek non-prescription solutions to your HBP.

I am an African American 62 yr old female. I was taking 10mg of lisinopril for 2wks and did experience lower bp, however I had the persistent cough, stomach pain, dizziness and depression. Saw doctor yesterday and was taken off. Now going to try Losartan.

10 points for Pam.

Thank You…

I was recently put on Lisinopril, 5mg a day, along with another BP med that I have been on for a long time. The doctor wants to get my BP down lower than the 130s. I am encouraged by the info on alternative non-drug options. I am hoping that excersizing, adding garlic and cayenne pepper, and cutting back on sugar will allow me to reduce the dose and eventually eliminate the need for Lisinopril. It’s scary to read about the possible risks of taking it!

I’ve only been on Lisinopril 10 mg once a day, for only a week. The carvedilol 3.5 was not doing it’s job, and the BP was way up. First day taking the Lisinopril I had gut pain like I was in labor 10/10, and comparable to my pain I had with C. Difficile infection a year ago. I think it’s doing it’s job as my BP has come down, but heart rate is up a bit, but I feel like a bucket of crap.

Heavy chest pain if feels like, sharp pains come and go. Yet the numbers are ok. I was told to take it easy, and I am, but it’s hard to even stand at times with the gut pain, headache, dizzy, and chest pain. Definitely going to check and see if there is an alternative after all I have read. I’m a white 50 yo female with long history of hypertension induced by stress.

Just to balance out some of the comments: (Almost everyone responding has had problems – not that this is unusual, as people naturally have a tendency to identify complaints & worries, but mostly don’t bother to report when things are ok or not worrisome.)

I have taken 20 mg Lisinopril for probably 10 to 15 years with none of the side effects described. When I get a cold with a cough, my cough lasts for weeks or months, but I can’t blame it on Lisinopril which I took before, during & after the cold, and the cough comes and goes, but it takes a while. I also take Bisoprolol HCTZ, but alone that wasn’t enough to get my blood pressure down. So I’ve been fine with this.

However, my husband was put on Lisinopril 5mg to combat his “fatty liver”. He used to have asthma, but now just gets bronchitis about once a year. However, he coughs constantly – sometimes productive, sometimes not. He seems to be inclined to ignore it; I think it shouldn’t be as constant as it is and will wear him down. (and his resistance to whatever germs may be about. He has Parkinson’s Disease and is a type 2 diabetic). It seems like he’s always coughing, more or less, and I can’t remember if it changes when he’s been on or off Lisinopril.

I think we should address this with his doctor, but could anyone suggest an alternative to combat fatty liver. His blood pressure is admirably perfect. Thanks.

I have been on Lisinopril for probably 7 years, maybe a little longer. I am on 5Mg daily. I haven’t had any problems and that dose doesn’t really take my pressure down a lot, but my doctor doesn’t want to give me more and I don’t want more. Sometimes my pressure is 150 or 160, but usually 130.

I do have moments when I am a bit dizzy if I turn quickly. And sometimes I feel like I am loosing balance briefly and I have wondered if that was causing it. I am 79 now. So I need to be very careful not to fall.

I will discuss this article and comments w/my doctor. Since it seems to be agreeing, I hate changing drugs, but would sure not want to have a sudden problem. I live alone.

I was on Lisinopril for a few years and experienced slight facial swelling a couple of times per year and thought nothing of it. Then recently, the swelling returned in exceedingly dramatic proportions. I went to the ER and the first three medics in the room all asked, “Are you taking Lisinopril?” That was the end of that Rx.

The stuff seemed to work fine otherwise, but no more ACE Inhibitors for me. I recently completed my participation in the SPRINT systolic blood pressure study and my BP is stable around 120/60 and holding without Lisinopril.

I have been taking 20 mg lisinopril for 2 months now and it has done a wonderful job of bringing down my blood pressure. While I sympathize with people who have had a bad reaction to it, you have to remember that these people are in the minority.

It bothers me when perfectly good drugs are removed from the market, just because a handful of people couldn’t tolerate them. Everyone reacts to drugs differently. The solution is to be aware of the possible side affects whenever you start on a new drug. Don’t punish the rest of us, who are benefiting from them, by taking them off the market.

In 2000, I had a heart attack, had a stent installed in the left rear of my heart, and was put on lisinopril. The Dr. said he did this to prevent my blood pressure from blowing the stent out in my heart. I have taken Lisinopril for years. I thought the dry cough was just me (I was a heavy smoker for over 30 years.) Just for laughs and giggles, I started keeping track of my blood sugar. It was high and I couldn’t understand why.

We are fulltime RVers. So, I made an appointment to see the local cardiolgist to find out if the lisinopril was the cause. The doctor said this happens in some heart patients. So, she switched me to Atorvastatin. I figured the problem was solved. A few years later, with another Dr. in another part of the country, I had a blood test and was told I am a Type 2 diabetic ( A1C 6.6 blood sugar was 175 or higher). I didn’t think much of it until I read your articles on side effects on certain drugs, namely Atorvastatin.

I quit taking it and my blood sugar came down to more normal levels within 30 days. I had a blood test for A1C in that 30 day period and it showed my A1C was 6.6. I know the test shows the glucose level for several months. I told my Dr. what I had about quitting the Atorvstatin and showed him how my sugar had come down to normal levels. He totally ignored what I had done. He put me back on Lisinopril and Metformin to help control my blood sugar.

I have COPD (emphysema). I can do without the dry cough. I can do without the high blood sugar. To say I am upset is putting it mildly. I am not a Dr. From doing my own research (with your help in your articles and reading the fine print on the drugs that I take), I find it appalling and what is worse is having a Dr. tell me that what he is doing is in my best interest and that my treatment is the MEDICAL STANDARD. REALLY?

Every time there is a drug commercial on TV, I shake my head at the list of side effects and that some of the side effects could kill you. What does one do? Change doctors until you find one that listens, or what?

I don’t know how long you been taking these drugs, but I read where some people have been taking them for 10 years before any side effects happen. That let’s me know it can happen anytime.

This medication caused me to have symptoms so scary I ended up in the ER once; after several doctors and 4 months, even an ENT doctor missed the cause, I finally researched and found out what my problem was on my own. Symptoms disappeared after ending the medication. Doctors then agreed with me, ” you are the doctor,” said one primary care doctor. I had been on Lisinopril for years before the constant dry non-productive cough and breathing problems started.

Long term use of ACE inhibitors also leads to congestive heart failure. There are many holistic products without negative side effects worthy of trying before resorting to a pharmaceutical solution.

Reading comments on Lisinopril, I wonder if comments are related to brand name or generic pills?
While the FDA complains about supplements having inconsistent / unreliable content, I wonder more about my prescriptions, like my generic Lisinopril and recent bouts of diahrrea. Whether side effects COME FROM ONE, THE OTHER, OR BOTH SOURCES WOULD BE GOOD TO KNOW.

One side effect from lisinopril, which is not mentioned in your article, is hyponatremia (an abnormally low level of sodium in the blood). As I learned, this can wreak havoc. Four months ago, the dizziness which I had been experiencing at times after starting lisinopril and my other BP meds (propranolol and amlodipine) became markedly worse – extreme vertigo at times, loss of balance, and “spaciness” to the extent that I fell twice. After two days, I went to the ER to evaluate my back which was not improving after the fall. Luckily, they ran blood tests and found my sodium level was dangerously low (122 vs. the normal 135-145). Hospitalized for four days while they slowly brought my levels back up to the point where I could go home, but still low. (To bring it back up quickly could have caused seizures).

A month later, it happened again, and another four-day hospital stay. Fortunately, a well-informed physician there identified lisinopril as the culprit and changed my medication regimen, prescribed salt tablets, and recommended eating high sodium foods. Have you ever had a doctor tell you to increase your salt intake? Hard to do after a lifetime of just the opposite! Just another example of meds harming more than they helped.

My husband also developed hyponatremia after taking lisinopril for 7 years. Not one doctor thought about lisinopril causing it. Until he needed medical clearance for a biopsy and the nephrologist said “stop taking lisinopril”, he had two years of testing for every disease you can imagine. The doctors were just scratching their heads. His levels came back to normal within a just a few days.

Regarding potential side effects, would you elaborate on what types of “blood disorders”?

Neutropenia and agranulocytosis are both possible serious side effects.

Diovan may be a good alternative. As always, check with your doctor before changing your medication.

As a registered pharmacist, I was aware of the angioedema side effect with liniopril; however, because the side effect was not “black boxed” the attention it needs is not highlighted. After taking the drug 20/12.5 htz for almost 15 years, I too had a life threatening angioedema side effect.

Started at 8:00 PM. By 10:00, I was in an emergency room unable to talk and having difficulty swallowing. Epinephrine will not help with this reaction. I was give IV steroids and by mid-night, I was well on the way to recovery. Spent the night in the ICU and was released the following morning at 11:00 AM. THIS PRODUCT SHOULD HAVE A BLACK BOX WARNING DUE TO THE DELAYED ALLERGIC REACTION PROBLEM. If I had been more than 2 hours from adequate medical care, I would be dead.

I was on lisinopril for a little over 3 months. I had horrible coughing and gagging day and night. Diarrhea (like a water faucet) daily. Nausea. Chest pain. I can’t believe they continue to give this medication to people. I stopped taking it and withing 3 or 4 days I was starting to feel normal again. PLEASE STOP TAKING THIS MEDICATION!

Have been on lisinopril for almost 2 months have been dizzy unbalanced and bad headache first couple weeks… Now I am tired all the time still off balanced and noticed my depression and anxiety getting much worse. I told my doctor and she tried giving me a different pill which can cause a heart attack in rare cases when initially starting on this med. I didn’t even take 1 pill stayed on the lisinopril but plan on talking to my Doctor again. How can they give out such a bad drug they really don’t have their patients best interest in mind at all. If they can’t find me something safer than it’s time to look for a new Dr. who will actually listen!!!!!!

I had the same experience. I took the benezapril for 5 months. I was sleep and woke up my throat was swelling. I went to the er and ended up in icu for 5 days on a ventilator til the swelling went down. It was a very scary ordeal. Who would think something that is suppose to save your life almost be your demise.

What are some good alternatives to Lisinopril for an African American male.

Back in November 2015 I had an allergic reaction to Lisinopril as well. Because of the swelling of my lips and throat they had to put a tube on my throat for several days and it caused scaring. I now have trachea stenosis. I’ve had 2 procedures done where they put in the laser balloons to widen my windpipe and that is only temporary the doctor says. Doctor told me he didn’t want to cut on me because it might cause more scaring but after I had my follow up he said I should find a doctor who can put stents in but that’s not guaranteed either,smh. He told me after my last procedure that in 3 months I will be worse again and that was in March. It’s August now. He don’t know my God!

This medication is not good at all. I almost Died! It is still hard for me to get over that day. Dr. Inform my husband that we made it just in time!!! I just hope that people read up on what they are taking!

This medication it’s not good at all I was on it for just one year. And I could not breathe my tongue came out my windpipe my throat everything was closed up. I was not gasping for air I was gurgling gurgling for air air. So emergency trach was not performed . They had to put a tube down my nose and it took everything in the process of them opening up my throat and windpipe. I was lucky that I made it there in time I’m still going through a whole lot with that day. Make sure that you read everything that goes in your mouth before you take it.

I just got out of the hospital yesterday after a 3 day stay. This is the second time in 5 months I have had severe diarrhea, vomiting and abdominal cramping. I have been diagnosed as having acute pancreatitis. There were many tests run and one of the things they came up with was gall stones although none were found, ” must have passed it” they said. My husband and I were not happy with the the fact that a real reason was not found for the cause of all this pain and suffering. I have also had serious puffy eyes, dizziness, ringing of the ears, serious joint pain , embarrassing flatulance and many other strange symptoms. I decided to look up symptoms of Lisonipril and saw that most if not all of my listed symptoms are side effects of this drug. I had been on an IV the entire time in the hospital and after a few days felt much better noticing a reduction in the eye puffiness and other symptoms for the first time in at least a year! Could it be the medication? I will be seeing my doctor in a few days and will ask that I get a different medication for high blood pressure. I take 20 mg per day. Wish me luck!

How can I wean myself off Lisinopril? Thanks, everyone for your stories and input. After reading, I believe this drug is causing my gastrointestinal problems and the raw, sore feelings in my mouth. With all my specialists, I get the same report, everything looks good! I have had every acid blocker on the market, with many making me sicker. My colonoscopy and endoscopy, reveal nothing, except a slight hiatel hernia. Actually, never had this issue, until I had my first endoscopy, three years ago and I thought it was acid escaping into my throat and mouth. This was same time frame they removed my thyroid and I have to take levothyroxine, also. This is the same time frame they put me on lisinopril. I cant wait to be free of lisinopril and see if my symptoms of sore burning throat and mouth, severe constipation, muscle weakness and weak sinking spells go away. I just want to get off this drug safely.

I have been on this medication for 5yrs.I have received experiencing the same symptoms everyone else has been discribing. I noticed it from the beginning of taking it,I mentioned it to my Dr.but he was not very concerned about it. I have been complaining about it for years. None of them have ever said that the meds,could be the problem.

I was prescribed 10 mg lisinopril for slightly hbp. After 2-3 weeks I noticed a gradually deepening depression. I mentioned this to my doctor and was told that was not a known side effect for this medication. A few minutes on the internet and I learn it is a fairly common claimed side effect. I tapered off the meds slowly for 2 weeks just to be safe and feel no depression whatsoever now. It would be impossible for me to function on this medication. The depression was that severe which could even be life threatening.

I started taking lisinopril a month ago once a day and I have felt OK until today, I am light headed (dizzy) whether I sit, stand, lay down and it’s scary. I’m trying to find out if its a side effect or is my bp dropping to low, should I not take it tomorrow? I have to go to work and I can’t work with the way I feel today.

I took lisinopril for a long time over 7 years. I began to feel unstable. Panic attacks confusion and terrible stomach pain. I was hospitalized twice. They tried to take out half of my colon. Said it was diverticulitis. I signed out of the hospital and had a colonoscopy done I was fine. I finally figured out it was the lisinopril. I can’t find another medication that doesn’t make me very sick now. But at least I have my colon..,. sad, and scary.

This could be a consequence of the blood pressure medicine. It deserves a discussion with your doctor.

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