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How to Ease Arthritic Knees with Natural Remedies

NSAIDs can ease pain in arthritic knees short term, but long-term side effects are troubling. Tai chi practice and natural approaches help.

Osteoarthritis puts its victims in a dreadful double bind. The nonsteroidal anti-inflammatory drugs (NSAIDs) that are the standard pain relievers for arthritis, such as diclofenac (Voltaren), ibuprofen (Advil, Motrin IB), meloxicam (Mobic) or naproxen (Aleve), can take the edge off in the short term, but long-term use has serious drawbacks. These drugs can cause irritation or even ulcers in the digestive tract; they also raise the risk for heart attacks or strokes (Circulation: Cardiovascular Quality and Outcomes, July 8, 2014). What can you do to soothe the pain in your arthritic knees without NSAIDs?

Study Supports Tai Chi to Ease Arthritis Pain

Experts estimate that nearly 400 million people suffer from knee osteoarthritis worldwide. Exercise is considered a cornerstone of knee osteoarthritis management. But what exercise is helpful and won’t further damage sore joints? People are understandably reluctant to jump into an exercise program if it might make things worse.

A new study randomized patients with knee arthritis to receive either online information about the benefits of exercise for arthritis or a tai chi program with a mobile app encouraging adherence to this kind of gentle exercise (JAMA Internal Medicine, Oct. 27, 2025). Researchers assigned 178 people with arthritic knees to the groups randomly. the study lasted 12 weeks, and participants in the tai chi group used the app to guide themselves through the Yang-style tai chi program. Having access to a self-guided exercise program was much less resource-intensive than having volunteers attend in-person tai chi classes.

man and woman practicing tai chi outdoors

Asian Couple practicing Tai Chi in the park together. Healthy, workout and relaxation concepts. Smiling Chinese or Thai or Japanese people.

The investigators report that

“This randomized clinical trial found that this unsupervised multimodal online tai chi intervention improved knee pain and function compared with the control at 12 weeks.”

They conclude that

“This free-to-access web-based intervention offers an effective, safe, accessible, and scalable option for guideline-recommended osteoarthritis exercise.”

Glucosamine, Chondroitin and Other Aids for Arthritic Knees

Q. Both my knees have been bone-on-bone for at least four years. I used to take chondroitin and glucosamine sulfate, a combo supplement. But I kept reading about tests showing “no benefit,” so I went off it.

Sure enough, the pain increased. When I got back on it, the pain decreased. I’m an expert double-diamond skier and I do know knee pain. I ski until my knees won’t let me!

My knees used to take about four days before they were “back to normal” after skiing. On glucosamine and chondroitin, it only takes about a day and a half. Shame on those who disparage the efficacy of this supplement!

To manage my knee pain, I also take gin-soaked raisins, Certo and grape juice, bromelain from pineapples, boswellia, turmeric, hyaluronic acid capsules, celery seed capsules and fish oil.

Some doctors I’ve seen have said: “Skiing? I have no idea how you’re even walking!” Yet I run up and down the stairs and do everything I want with, yes, a little bit of pain now and then but nothing to slow me down at all. Those supplements and remedies really do work! I’m a happy camper.

A. We are impressed with your dedication to skiing and your creative approach to managing knee pain. One word of caution, though: New research in the journal Nature Metabolism (June 9, 2026) suggests that glucosamine supplements may accelerate Alzheimer disease.

The researchers discovered that glucosamine given to genetically susceptible mice increased their likelihood of developing brain pathology. In addition, they analyzed the health records of people with Alzheimer’s disease. Those who took glucosamine had more rapid progression of their condition.
This concern may not apply to everyone, however. Those who seem most susceptible already have cognitive impairment.

Given the possible risk, you might want to rely more heavily on the other supplements and remedies you have mentioned. Others can read about these in our eGuide to Alternatives for Arthritis.

Natural Remedies for Arthritic Knees

Q. I have arthritis in my left knee. My last X-ray three weeks ago showed bone on bone, but I have had little discomfort.

I am planning to travel internationally and will do a lot of walking. My doctor will administer a cortisone shot in my knee next week in preparation; however, I would like to take something with me in case all the walking causes swelling and/or pain.

Good walking shoes and a trekking stick should help, but I do not want to hold up the group if I have too much pain. Do you have suggestions of a non-drug remedy for pain/swelling?

Herbal Therapies for Arthritis Pain

A. You might consider boswellia and/or turmeric capsules to reduce inflammation. A systematic review and meta-analysis found that the active ingredients in turmeric (curcuminoids) are “associated with better pain relief than NSAIDs” (Complementary Therapies in Medicine, Dec. 2021). The authors included 11 studies with a total of 1,258 participants in their analysis. These were people with knee osteoarthritis (OA).

The conclusions:

“The results of our meta-analysis suggest that curcuminoids are effective in pain relief in knee OA and that low- and high-dose curcuminoids have similar effects in improving pain and AEs [adverse events]. Curcuminoids are also more effective in achieving pain relief than NSAIDs; therefore, using curcuminoids as an adjunctive treatment in knee OA is recommended.”

Turmeric and the active curcuminoids may interact with anticoagulant medications such as warfarin. People should always ask the pharmacist whether any of their medications would be incompatible with turmeric.

Finding Quality Products

We are frequently asked which turmeric product we recommend. Until recently, we have been cautious not to recommend a particular brand. That’s because it has been hard to verify quality. During the pandemic, products from abroad have been particularly worrisome because of a lack of FDA oversight. And it is hard to know where the ingredients in any particular product come from.

We had an opportunity to visit the Gaia Herbs farm in the mountains of North Carolina. Our intention was to see what the farm was like and what their commitment to quality was all about. We were extremely impressed. Here is a link to what we discovered during our visit.

This is all by way of saying that we think their Turmeric Supreme Joint Health formulation is terrific. It contains turmeric plus black pepper to aid absorption of curcuminoids. There is also boswellia, devil’s claw, ginger root and quercetin. Here is a link.

As another option, you might consider their Turmeric Supreme Extra Strength Gummies. These tasty gummies don’t require you to swallow a pill.

Another Option

Many people like to use Certo or powdered plant pectin dissolved in grape juice. Unless you can purchase grape juice while traveling, though, this approach could be cumbersome. Cherry juice has the same drawback, but it is possible to buy tart cherry extract in pill form or as a fruit bar.

We are sending you our Guide to Alternatives for Arthritis with these suggestions and others. Some people find glucosamine sulfate, alone or in combination with chondroitin sulfate, can be helpful (American Journal of Sports Medicine, March, 2015).

A randomized controlled trial from Italy found that a combination of methylsulfonylmethane (MSM-5 gm/day) and boswellic acid (BA-7.2 gm/day) worked as well as 1500 mg of glucosamine sulfate per day to relieve the pain of arthritic knees (International Journal of Immunopathology and Pharmacology, March, 2016).

Citations
  • Bavry AA et al, "Nonsteroidal anti-inflammatory drugs and cardiovascular outcomes in women: Results from the Women’s Health Initiative." Circulation: Cardiovascular Quality and Outcomes, July 8, 2014. https://doi.org/10.1161/CIRCOUTCOMES.113.000800
  • Zhu SJ et al, "Online unsupervised tai chi intervention for knee pain and function in people with knee osteoarthritis: The RETREAT randomized clinical trial." JAMA Internal Medicine, Oct. 27, 2025. DOI: 10.1001/jamainternmed.2025.5723
  • Hawkinson TR et al, "Hyperglycosylation is a metabolic driver of Alzheimer's disease." Nature Metabolism, June 9, 2026. https://pubmed.ncbi.nlm.nih.gov/42265388/
  • Hsiao A-F et al, "The efficacy of high- and low-dose curcumin in knee osteoarthritis: A systematic review and meta-analysis." Complementary Therapies in Medicine, Dec. 2021. DOI: 10.1016/j.ctim.2021.102775
  • Gallagher B et al, "Chondroprotection and the prevention of osteoarthritis progression of the knee: a systematic review of treatment agents." American Journal of Sports Medicine, March, 2015. DOI: 10.1177/0363546514533777
  • Notarnicola A et al, "Methylsulfonylmethane and boswellic acids versus glucosamine sulfate in the treatment of knee arthritis: Randomized trial." International Journal of Immunopathology and Pharmacology, March, 2016. DOI: 10.1177/0394632015622215
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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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