Parents often worry about the possible side effects of drugs prescribed for attention deficit/hyperactivity disorder (ADHD). Often they are reassured that there are no serious problems, but a new study of Korean youngsters conducted by scientists at the University of South Australia found a link between methylphenidate (Concerta, Daytrana, Metadate, Ritalin) and heart rhythm changes.
How Did They Study Ritalin & Kids’ Hearts?
The South Korea National Health Insurance Database had information on more than 100,000 children up to age 17. Their records between 2008 and 2011 were scrutinized to detect possible adverse events. The team noted more than 1,000 cardiac events among children taking methylphenidate. Arrhythmias were the most common of these.
According to Senior Research Professor Libby Roughead of the Sansom Institute for Health Research,
“What we showed was that there is an increased risk of arrhythmia…and this is more pronounced in children who have existing cardiovascular disease or are on some other medicines that can also affect the heart…What parents should know is that they should monitor simple things like blood pressure and heart rate after taking the medicine and before. If they start to feel nervous they should talk to their doctor.”
Overall, the absolute risk is low. Even with a 60 percent relative risk increase, problems with kids’ hearts are quite rare. The arrhythmias were more likely among children beginning to take methylphenidate, in the first three days of treatment.
Who Takes Ritalin?
There are more than 6 million children in the U.S. who have been diagnosed with ADHD. Not all of them take medication, and of those that do, not all take Ritalin or similar drugs. This research suggests, however, that parents of children with existing heart problems as well as ADHD might wish to search for a different way of treating them.
Because the study is observational rather than experimental, Professor Roughead warns that parents should not rush to change their children’s medications.
“What I think the study underlines is the need to consider the severity of ADHD symptoms and the option of non-stimulant treatments for children with high cardiovascular risk.”
The scientists from the University of South Australia collaborated with investigators from McGill University and the Jewish General Hospital in Canada and the Seoul National University in Korea.
We were alerted to this story by an article in The Lead, South Australia.