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How Can You Control Yeast Overgrowth?

When yeast overgrowth causes irritation at the corners of the mouth, antifungal ointment and a diet low in refined grains and sugar may help.
How Can You Control Yeast Overgrowth?
Skin problems, angulitis, angular stomatitis, angular cheilitis  a disease of the mucous membrane and skin of the corners of the mouth, caused by streptococci.

Do you ever develop painful cracks at the corners of your mouth? Doctors call this symptom perlèche or angular cheilitis. Treating it effectively can be challenging. In some cases, you will need to figure out how to control yeast overgrowth.

Controlling Yeast Overgrowth:

Q. I have an ongoing problem with yeast overgrowth on both sides of my mouth. This has been a problem for nearly a year.

I’ve seen the dermatologist multiple times, and she diagnosed my condition as yeast.

We have tried various topical creams. The only one that does any good is a combination of clotrimazole and betamethasone. Unfortunately, she says I should not use it long term.

The pills she would like to prescribe either contain titanium dioxide, to which I’m allergic, or cost over $300. I’m retired and living on social security. I can’t afford to spend money on pills that might not work. Please help!

Treating Angular Cheilitis:

A. It sounds like you are describing angular cheilitis, painful cracks at the corners of the mouth. Yeast overgrowth often causes this condition. Sometimes, however, people who have become deficient in zinc, vitamin B2 or vitamin B12 will respond to supplements.

The clotrimazole your dermatologist prescribed has strong antifungal activity.  You may have already tried other antifungal ointments, such as miconazole (Micatin, Monistat, Zeasorb).

Other readers have reported success treating the cracked corners of their mouths with amber Listerine. This old-fashioned mouthwash contains essential oils with antifungal activity. Because yeast is a form of fungus, this can sometimes be helpful.

One common type of yeast that grows on human skin, Malassezia, triggers the immune system to produce interleukin 17 (IL-17) and create inflammation (Cell Host & Microbe, March 13, 2019). This reaction contributes to eczema as well as to angular cheilitis and, possibly, psoriasis (International Journal of Molecular Sciences, Feb. 13, 2020).

Discouraging Yeast Overgrowth:

In addition to applying Listerine or an antifungal ointment to the corners of your mouth, you might want to try a different diet. Dogs get ear infections when Malassezia gets out of control, and an antioxidant, anti-inflammatory diet can help (Veterinary Research Communications, March 2016). While people and dogs are quite different, we have heard from some readers that cutting out refined grains and sugars reduces yeast overgrowth. This approach may help control the redness and irritation you suffer.

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies. .
  • Sparber F et al, "The skin commensal yeast Malassezia triggers a type 17 response that coordinates anti-fungal immunity and exacerbates skin inflammation." Cell Host & Microbe, March 13, 2019. DOI: 10.1016/j.chom.2019.02.002
  • Furue M et al, "Interleukin-17A and keratinocytes in psoriasis." International Journal of Molecular Sciences, Feb. 13, 2020. DOI: 10.3390/ijms21041275
  • Di Cerbo A et al, "Clinical evaluation of an antiinflammatory and antioxidant diet effect in 30 dogs affected by chronic otitis externa: Preliminary results." Veterinary Research Communications, March 2016. DOI: 10.1007/s11259-015-9651-4
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