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Bupropion Helps With Mood, Sex and Quitting Smoking

A nurse badly wants to quit smoking. Chantix makes her miserable. Bupropion helps against cravings and improves her mood. Others report sex is enjoyable.

Bupropion (Wellbutrin) was first approved by the FDA in 1985 to treat depression. It remains a totally unique antidepressant. There is no similar antidepressant on the market. Unlike SSRI and SNRI antidepressants such as citalopram, duloxetine, fluoxetine and sertraline, bupropion is far less likely to interfere with love making. In addition, bupropion helps people stop smoking, as this reader reports:

Chantix vs. Bupropion to Quit Cigs:

Q. I am a nurse who has smoked for 17 years. I used to enjoy it. As a single mom, smoking sometimes felt like my only friend.

Now I hate it. I get embarrassed lighting up in public, and I hate to think of the amount of money I have spent not only on cigs but also on body sprays, air fresheners, teeth whiteners, etc.

I tried Chantix when it first came out and it was horrible. I had nightmares, suicidal thoughts and didn’t care about anything. I thought smoking was better than these side effects.

This time around I started Wellbutrin, which is equivalent to Zyban. It has been so much better. My mood has been on an even keel. It’s been a week and I am down to four cigs a day.

Bupropion Helps Do Double Duty:

A. We congratulate you on trying to quit smoking. It is one of the most important things you can do for your health.

Bupropion (Wellbutrin, Zyban) is prescribed to help people stop smoking. It may take two to three months of treatment to overcome the habit. Bupropion is also prescribed for depression, which might explain your stable mood.

Wellbutrin: Tale of Woe and Intrigue:

Wellbutrin (bupropion) has had a checkered career as an antidepressant. It originally had to be taken three times a day. That made it a slow starter compared to drugs like Prozac (fluoxetine) and Zoloft (sertraline). People like to take one pill a day and forget about it.

Eventually a slow release (SR) form of bupropion was developed. It only had to be taken twice a day. That made it a little more convenient and sales picked up. Eventually a once-a-day formulation was introduced (XL). Wellbutrin XL 300 became very popular.

When Wellbutrin XL 300 lost its patent, generic formulations came along. There is a tale of woe and intrigue about some of those products. We were directly involved in getting the FDA to investigate this scandal. Eventually, products were removed from the market. You can read all about this debacle at this link.

We fear that the FDA has let down its guard…again. We have been hearing complaints about generic bupropion…again. Here is a link to the ongoing saga of generic bupropion.

Bupropion Helps Against Depression:

We have heard from many readers that bupropion helps against depression. In some cases, people discover that bupropion helps rather than hinders love making.

Rebecca in Washington shares her story:

“I’ve suffered from severe depression for over a decade. I’ve tried three different prescriptions over that time. None of them helped. Two had negative side effects.

“I started bupropion about 3 months ago, and it has been an absolute miracle worker. I’m happier than I’ve been in a very, very long time. The only negative side effect I experienced was an increase in the migraines that I already had. Even that went away after a few weeks.

“As for increasing libido, yes. It definitely did that for me, although I honestly might consider that a negative too, because for a while it got to the point where I couldn’t focus on anything else. I guess some people would probably enjoy that though.”

More Reader Comments:

Please share your own bupropion story in the comment section below. Have you found that bupropion helps with depression, smoking cessation or love making? Have you experienced side effects? Let others benefit from your experience.

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About the Author
Joe Graedon is a pharmacologist who has dedicated his career to making drug information understandable to consumers. His best-selling book, The People’s Pharmacy, was published in 1976 and led to a syndicated newspaper column, syndicated public radio show and web site. In 2006, Long Island University awarded him an honorary doctorate as “one of the country's leading drug experts for the consumer.”.
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