You will hear the highlights of Dr. Bianco’s discussion of the genetic differences among human beings that have an impact on thyroid well being on Show 1015: Thyroid Mysteries, Controversies and the Latest Research. His thyroid research shows that these alterations in our genetic makeup affect how easily we convert the four-iodine thyroid hormone T4 (levothyroxine) to the active three-iodine thyroid hormone T3 (triiodothyronine). What effects do these changes have on the standard tests for thyroid function and on patients’ feelings of wellbeing?
There just wasn’t enough time for his entire interview in the show, so we offer it here. You can listen to the entire unedited interview and learn more about the thyroid gland and thyroid research than you ever imagined.
Antonio Bianco, MD, PhD, is head of the division of Endocrinology and Metabolism at Rush University Medical Center. His articles include: “Coordination of hypothalamic and pituitary T3 production regulates TSH expression.” Journal of Clinical Investigation, April, 2013; “Cracking the code for thyroid hormone signaling.” Trans American Clinical and Climatological Association, 2013; “Defending plasma T3 is a biological priority.” Clinical Endocrinology, Nov. 2014; “Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine.” Journal of Clinical Investigation, Feb. 2015; “Coupling between nutrient availability and thyroid hormone activation.” Journal of Biological Chemistry, online Oct. 23, 2015; and many others.
Dr. Bianco also co-chaired an American Thyroid Association task force that updated the guidelines for treating hypothyroidism. They were published in the journal Thyroid.
If you enjoy Dr. Bianco’s interview, you may also want to listen to Dr. Ridha Arem on how to achieve thyroid balance.