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Are Older People Taking the Wrong Medicines?

Studies suggest that too many older people end up taking the wrong medicines, such as benzodiazepines, that may not offer them much benefit.
Senior Man, arms crossed, looks down at large assortment of prescription bottles pills

Many senior citizens may be taking the wrong medicines. Those who can least defend themselves-those with cognitive difficulties or dementia-may be running the greatest risk.

Are People with Dementia Being Given the Wrong Medicines?

A study from Europe reveals that many older people with dementia are prescribed inappropriate medications (Renom-Guiteras et al, Age and Ageing, Sept. 1, 2017). More than 2,000 individuals were assessed. Roughly 60 percent of them were taking at least one unsuitable drug. Over one fourth were getting two or more such medicines.

Which Medicines May Be Inappropriate?

These drugs include powerful acid suppressing drugs called proton pump inhibitors, antipsychotic medicines, sedatives and sleeping pills, particularly benzodiazepines. People in long-term care facilities appear to be at greatest risk for receiving inappropriate medications.

Older people are at risk for the wrong medicines in the US as well as in Europe. A few years ago we got this question from a reader:

Is Mother Being Overmedicated?

Q. My mother has always been active but lately she seems to be fading. She complains about insomnia and dizziness.

Her doctor recently prescribed bupropion and she had horrible side effects: trembling, heart palpitations, double vision, weakness and constipation. As a result, I think, her insomnia trouble was exacerbated.

Her doctor did not believe the drug could be causing these problems, but he prescribed lorazepam to help her sleep. (It doesn’t help much.)

She takes simvastatin for high cholesterol, baby aspirin for her heart and Tylenol for joint pain. She is also on clorazepate for anxiety.

My main concern is whether my mother is being overmedicated. Do you have any information on how these medicines would affect an older person?

Are These the Wrong Medicines for an Older Woman?

A. The antidepressant bupropion can cause agitation along with the other symptoms your mother has experienced, including the insomnia. Prescribing a medication to treat the side effects rather than changing the medication causing the problems doesn’t make much sense to us.

Benzodizepines and Dementia:

We are particularly concerned about her taking two benzodiazepines (lorazepam and clorazepate), since these could contribute to dizziness and unsteadiness and are usually inappropriate for the elderly. An important study found that mature people taking benzodiazepines are at elevated risk of Alzheimer disease (Billioti de Gage et al, BMJ, Sept. 9, 2014). Conversely, as Alzheimer disease worsens, people are more likely to be prescribed benzodiazepines, presumably to calm them down (Tormalheto et al, International Psychogeriatrics, Oct. 2017).

Our Guide to Drugs and Older People provides information on many more drugs that can be dangerous for those over 65.

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies. .
Drugs and Older People

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My aunt was doing poorly in Florida so I took my mother on a fall trip to see her in 2009. I was asked to review the meds. She had 6 OTC’s, 25 prescribed drugs with various dangerous or negating interactions and she was barely able to get out of bed. After spending an afternoon documenting what her primary care doc knew, but would not change because “specialists” had prescribed the drugs, my aunt woke up and entered the conversation. I told her she needed 2 OTC’s at most, and less than a handful of prescriptions. Her response was out of the Jefferson Airplane song – “that’s alright, those don’t do anything anyway – the good drugs are by my bed.” The medication taper was painful and required ED visits but my aunt got off most of the benzos, narcotics and sleepers as well as most of the other multi-specialty Rx mess, woke up and lived pretty well over 5 years.

Add donepizil.. causes nightmares and aggression. Doesn’t help with memory

I wonder if seniors aren’t made to keep their blood pressure too low, especially those with mild dementia or balance problems.

I don’t know if this in line with what was said
But I am female 86 years and recently had a TIA
Cholesterol and trig triglycerides are perfect yet a statin was prescribed
What do you think
Don’t like statins and feel it’s not necessary
Yet don’t want another TIA or worse

My druggist, far more than any of my physicians, knows the side effects and the interactions among the prescritions that I take. I am not worred. But I am worried about the ones I prescribe myself – supplements. I currently seem to fall for any sort of advertising or report that promises relief from pain, arthritis, inflammation and so on.

I take a large number of supplements, and I don’t know anyone who can tell me if I am missing any, duplicating the ones I take, taking ones that conflict with others, and so on. Physicians are not trained in this. Locally I can’t find a naturopath, who might be able to help me. Online it’s about selling me something. Where can I get the straight dope on supplements?

William – You are right to be concerned about the number and possible interactions of your supplements. The best DIY resource for getting solid info is Consumer Lab — Google it. You can look up almost any supplements and get current, reliable info. At least this should help you to prune that list a little :).

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