Cocoa pod being harvested, cocoa flavanols, cocoa flavonoids

Cocoa flavonoids may have some benefit for people with multiple sclerosis, according to a small study in the Journal of Neurology, Neurosurgery & Psychiatry (March 4, 2019). These antioxidant compounds from cacao have shown promise in fighting inflammation, preventing blood clots, regulating the immune system and helping blood vessel linings relax, lowering blood pressure (Becker et al, Frontiers in Pharmacology, Dec. 12, 2013). 

Cocoa Flavonoids Against Fatigue:

A previous study had shown that dark chocolate rich in cocoa compounds could improve symptoms of chronic fatigue (Sathyapalan et al, Nutrition Journal, Nov. 22, 2010). The investigators wondered whether cocoa flavonoids might also help people with the fatigue and fatiguability associated with MS.

To find out, they recruited 40 people with relapsing remitting MS. These individuals drank cocoa prepared with rice milk every day for six weeks. Nineteen of them got high-flavonoid cocoa, while 21 drank low-flavonoid cocoa and served as a control group.

At the end of the study, those on the high-flavonoid cocoa had slightly less fatigue. Their fatiguability was measured by how far they could walk in six minutes. Those who had consumed the high-flavonoid beverage could walk farther in six minutes than they had at the outset. The improvement was 80 percent greater for those in the intervention group than for those in the control group. People in the high-flavonoid group also reported less pain. 

This preliminary research will need to be replicated before we can conclude that cocoa is helpful for MS, however. The investigators hope to recruit 80 people with MS for their next, more powerful, study of cocoa flavonoids.

Get The Graedons' Favorite Home Remedies Health Guide for FREE

Join our daily email newsletter with breaking health news, prescription drug information, home remedies AND you'll get a copy of our brand new full-length health guide — for FREE!

  1. Jamie

    Dark chocolate with a high percentage number or plain cocoa powder has the highest amount of beneficial antioxidants. Milk chocolate or Dutch processed cocoa (label may state processed with alkali) are not as beneficial.

  2. John

    For those thinking of making hot chocolate consider that the heat could be destroying some of the vital nutrients that you are hoping will help you.

    I buy organic raw cacao powder or cacao nibs (grind the nibs up in a coffee grinder to be more of a powder) and add one tbsp to my granola every day. It tastes good, like having chocolate milk granola. I order online and use a brand sourced from small farms in Peru where the heavy metals are at least lower in quantity. And the cacao nibs are supposed to contain less cadmium than the cacao powder.

    The raw cacao is processed at less than 110F so heat shouldn’t be a factor unless you go and mix the cacao in hot water.

  3. sandi

    I like cocoa nibs.

  4. Marilyn
    Laguna Hills, CA

    Re shingles, my husband’s doctor gave him an IV drip with Lycine, C, and a few other things I don’t remember. We believe it helped him heal faster and without the post-herpies pains. Once in a while he feels a little something and he takes an L-Lycine tablet that seems to help.

  5. Virginia

    For those of us who would like to start on this regimen while studies continue, what constitutes a “high flavonoid cocoa drink”?

  6. Don

    Wouldn’t it be better to use cacao, the unprocessed form of cocoa powder to get the benefits?

  7. Shirley

    I live in a graduated-care senior living apartment, and several of my friends are here because of MS. They’re wondering how to get the cocoa flavonoids that you said might help them move more easily. Would it work to buy a carton of dark cocoa powder and mix it with hot coffee or hot milk? Or is there a pill or some other way to buy it?

  8. Barbara E.

    I am entering my 3rd year of Shingles pain. Took Gabapentin for about a year but too many side effects. Does anyone know of a natural way to reduce the burning, stabbing and numbing pain of Shingles after it should be gone?

What Do You Think?

We invite you to share your thoughts with others, but remember that our comment section is a public forum. Please do not use your full first and last name if you want to keep details of your medical history anonymous. A first name and last initial or a pseudonym is acceptable. Advice from other commenters on this website is not a substitute for medical attention. Do not stop any medicine without checking with the prescriber. Stopping medication suddenly could result in serious harm. We expect comments to be civil in tone and language. By commenting, you agree to abide by our commenting policy and website terms & conditions. Comments that do not follow these policies will not be posted. Learn how your comment data is processed.

Your cart

Shipping and discount codes are added at checkout.