white lab mouse, prevent Alzheimer disease, mice

Mouse research suggests a possible innovation for treating post-traumatic stress disorder-at least in mice. For them, aromatherapy with a whiff of orange seems to make a difference.

How Did a Whiff of Orange Help?

The scientists used essential oil of orange in their experiments. Mice were conditioned to exhibit a fear response to a certain sound. They demonstrate their fear by freezing motionless for a certain period of time.

Exposing them to a whiff of orange essential oil 40 minutes before and 40 minutes after the initial sound exposure reduced this fear behavior significantly compared to mice exposed to water or those who simply were subjected to the sound. Challenging the mice with a bacterial toxin and measuring the immune response led the scientists to conclude that the scent of orange essential oil modulates the neuroimmune response.

Experimental Biology meeting, April 24, 2017, Chicago, IL

Will a Whiff of Orange Help Humans?

Although orange essential oil seems to be beneficial for mice, we have no idea whether it would help humans at all. Still, you might consider peeling an orange and getting a whiff of orange scent as a way to relax at the end of a stressful day.

In this research, the scientists were interested in learning whether inflammatory responses by immune cells contribute to post-traumatic stress disorder. The experiment suppors that hypothesis.

Get The Graedons' Favorite Home Remedies Health Guide for FREE

Join our daily email newsletter with breaking health news, prescription drug information, home remedies AND you'll get a copy of our brand new full-length health guide — for FREE!

  1. Hannah

    Essential oil of orange — a new kind of “liquid courage!” I’ll have to try this the next time I have to speak in front of a group. Extra bonus — I’ll smell nice.

  2. Jeannine
    New York

    For sure essential oils work on humans , I have a car air defusior and I happen to have Orange as my oil that I apply… It allows me to tell all the wrongs out there in a more positive way , as I safley drive !!! Peace & love ur way. Jeannine !!! (-,-)

  3. Geo
    Toronto Canada

    I remember while travelling in France having a shockingly painful headache. I was in Nice and with a friend ducked into a quiet restaurant for something hot like a soup thinking it would settle down. The server mentioned mandarin tea was commonly used for headache and stress, would I like this??

    My friend ordered a plate of french fries, and the chef was dispatched from the upstairs to prepare them. I had my tea finished and realized my appetite was returning. When the turkey size platter of french fries came to the table, I appreciated my friends gusto and tried a corner of the plate myself. I use essential oil of Blood Orange for sick head feelings and of course Peppermint for this also. G

  4. Chris N

    I was not aware that the health risks from the smell of oranges was so great that we had to test it on mice before concluding it was safe for humans.

What Do You Think?

We invite you to share your thoughts with others, but remember that our comment section is a public forum. Please do not use your full first and last name if you want to keep details of your medical history anonymous. A first name and last initial or a pseudonym is acceptable. Advice from other commenters on this website is not a substitute for medical attention. Do not stop any medicine without checking with the prescriber. Stopping medication suddenly could result in serious harm. We expect comments to be civil in tone and language. By commenting, you agree to abide by our commenting policy and website terms & conditions. Comments that do not follow these policies will not be posted.

Your cart

Shipping and discount codes are added at checkout.