Q. I was very concerned to hear on television that you should not eat peppermints while taking a cholesterol-lowering medication. I am on Crestor, and I eat peppermints when I have an upset stomach.
I called my pharmacist to ask what could happen and she wasn’t aware of any problems caused by taking a cholesterol medication and eating peppermint. Can you please tell me what could happen?

A. Mint is somewhat similar to grapefruit in its effect on certain statin drugs. One study revealed that peppermint oil increases blood levels of felodipine (Plendil), which is used as a model for this type of drug interaction (Clinical Pharmacology and Therapeutics, Sept. 2002).
Extrapolating from this research, one might expect that certain cholesterol-lowering drugs such as atorvastatin (Lipitor), lovastatin (Mevacor) and simvastatin (Zocor) might also be affected by peppermint oil. Crestor is unaffected by this interaction, so you have nothing to worry about.
Menthol also appears to have a similar effect. Someone consuming a lot of cough drops might need to be aware of this potential drug interaction.

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  1. Dianne S

    Are there any side effects from Crestor? This is issued In Australia.

  2. GK

    How does peppermint affect the supplement red yeast rice? I put a few dried peppermint leaves in my early morning tea every day.

  3. Barry F. RN

    Regarding your article on Statin Drugs being safe. I was on Lipitor, and Tricor for many years, when my fingers started cracking open with severe pain. I was told by 3 Dermatologists that it was strictly excema. Due to my condition I was forced to leave my job as an ER Nurse .
    I finally got so fed up that I went to the Veterans Hospital in West Palm Beach, where the Dr. did a CPK level. The level was off the charts, and I was immediately taken off the Statins . These days I have been on Lovaza 4gm and Niaspan 1000mg. with excellent results.
    My hands will never allow me to work as a Critical nurse, as the damage is permanent due to the muscle damage, but at least they have improved to the point where I can function as a nursing Supervisor.
    Thank you !
    Barry F., RN

  4. sandi

    What about peppermint tea?

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