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Joe Graedon - September 10, 2026

Pelacarsen Failure: Heart Drug Lowers Lp(a) but NOT Heart Attacks

Joe Graedon - September 21, 2026 - 16 comments

What High Lp(a) Means Now: Risk Is Real, Treatment Is Murky

The Pelacarsen heart trial failed miserably. Now doctors wonder if lowering high Lp(a) matters though a heart attack connection seems strong.