The People's Perspective on Medicine

More Drug Recalls From India – Do You Trust Foreign-Made Generics?

This past week two Indian Generic Drug Companies were told to recall medications because of manufacturing problems. This is just the tip of a big iceberg.

The overwhelming majority of generic drugs are now made abroad. India supplies a large proportion of those formulations. In recent days two large Indian drug companies have received bad news from the U.S. Food and Drug Administration. Dr. Reddy’s Laboratories has drug recalls for certain lots of a heart medication containing amlodipine and atorvastatin as well as the anti-seizure drug divalproex.

Divalproex sodium ER is the generic name for a long-acting epilepsy medicine sold under the brand name Depakote. Apparently the generic formulation from Dr. Reddy is too strong. On the other hand, the heart medicine containing amlodipine and atorvastatin, sold under the brand name Caduet, was not strong enough, hence the drug recalls of this sub-potent combination product.

This is not the first time Dr. Reddy’s manufacturing process has been questioned. Last year the company recalled thousands of bottles of the heart medicine metoprolol succinate, a beta blocker sold under the brand name Toprol XL. That’s because the generic formulation failed dissolution tests. Other problems at Dr. Reddy have included recalls of ranitidine (Zantac) and pantoprazole (Protonix).

The FDA has also banned importation of medications from another Indian drug company this week, Emcure Pharmaceuticals. The plant in Hinjewadi failed to meet quality standards for good manufacturing practices. Trying to find out about such drug recalls is challenging since the FDA does not make that information readily available.

 Generic Drug Recalls: Tip of the Iceberg

These latest generic drug recalls are just the most recent of a long list of problems. Last year the FDA sent out 18 warning letters about problems with good manufacturing process. Six went to Indian companies and six went to Chinese companies.

Over a decade ago one of the largest generic drug manufacturers in the world, Ranbaxy of India, was found to have fabricated data at a number of plants. Dozens of drug products had to be pulled from U.S. pharmacy shelves because of the fraud. Eventually, the company paid $500 million in fines and penalties.

Sun Pharma, another Indian generic drug company got into trouble because of disclosure issues and manufacturing problems. Zydus Cadila, Aurobindo, Wockhardt, Amsal Chem, RPG, Kamud Drugs, Posh Chemicals, Yag Mag Labs and Sun Pharmaceutical Industries have all had problems with the FDA.

According to the FDA there are 526 drug manufacturing plants in India making products for the U.S. market. The agency has 10 investigators to cover the entire country, and that is up from past years when there were even fewer FDA feet on the ground. China has 517 drug manufacturing plants making products that will end up in the U.S. market. At last count there were three investigators for the entire country, though that is supposed to eventually increase to 13. Does that give you comfort?

From our perspective the FDA is woefully understaffed abroad, so it is hardly any wonder that there might be problems with generic drugs made in India, China, Slovakia, Brazil, or goodness knows where.

An Even Bigger Generic Drug Disaster

More alarming than the manufacturing mess-ups and drug recalls is the possibility that clinical research organizations (CROs) that conduct generic drug studies may not be meeting quality standards. These are the companies that give generic drugs to dozens of volunteers and then measure their blood levels to determine if the generic drug is getting into the blood stream at the same rate and amount as the brand name drug that is being copied.

The World Health Organization discovered serious problems at one of the largest organizations, GVK Biosciences in India. The European Medicines Agency accused the company of faking data on roughly 700 different generic drugs from dozens of generic drug companies over a five-year period. As a result of the investigation, European regulators disallowed hundreds of generic drugs based on those clinical trials.

We suspect that the FDA has also relied on data supplied by GVK Biosciences. We asked the agency about these problems and have not received an adequate response. The FDA has not been very forthcoming about generic drugs it might have approved based on GVK data. We don’t understand why the FDA hasn’t disallowed most of the generic drugs tested in GVK facilities. If the European regulators doubt the accuracy of the data, shouldn’t we?

Now, a different company, Quest Life Sciences, has also been warned about defective trials. How this might affect generic drugs in the United States is unknown because once again the FDA has not made its investigations public.

The Bottom Line

The FDA is opaque when it comes to revealing generic drug problems. When a company gets busted for fraud or bad manufacturing practices, the U.S. Food and Drug administration often redacts critical information from its official forms. That means the feds black out key data such as which drugs are involved in a recall or what the specific problems were. The agency also hides the bioequivalence data used to support its generic drug approvals. The justification seems to be that the data is “proprietary.”

We do not get that. If there are problems with generic drugs, we should be able to know the details so we can pass them along to you. And we believe that every generic drug the FDA approves should have its bioequivalence curves and data made available for public scrutiny. We also think the country of origin should be listed on every drug product sold in the U.S. If you are informed about where your shirt is made or where the plums you eat are grown, why not the medicine you purchase?

It is time for the FDA and the generic drug industry to make everything transparent so doctors, pharmacists, nurses and patients can see what’s going on for themselves. Until that happens, we fear the American public will have serious doubts about generic drug quality. If you agree, let the leadership of the FDA know. Send a message to the Director of the Office of Generic Drugs, Kathleen Uhl, M.D. Her email address is:

If you have ever had problems with a generic drug, please let Dr. Uhl know.

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About the Author
Joe Graedon is a pharmacologist who has dedicated his career to making drug information understandable to consumers. His best-selling book, The People’s Pharmacy, was published in 1976 and led to a syndicated newspaper column, syndicated public radio show and web site. In 2006, Long Island University awarded him an honorary doctorate as “one of the country's leading drug experts for the consumer.” .
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I have been taking generic Effexor and Lorazepam from some unknown-to-me manufacturer. My depression is worse, and the lorazepam–I could eat candy, and it would do as much for me. How can I complain?

I am concerned about my drug that has been switched to generic because of cost. I was taking MicardisHCT80/12.5 and switched to generic because of the inflammatory rise of price. Am now taking Telmisa HCTZ 80/12.5 TAB. Is this ok health wise?

Here I am trying to figure out why my blood pressure is up. I am exercising and eating correctly, no unusual tension. I did notice that the appearance of my Losartan 25 mg. had changed from a green pill to a white pill. Camber Pharmaceutical produces this medication out of India. I have spent the last several minutes with a representative from India. The New Jersey telephone receptionist connected me with her. Although she speaks English, it is hard for us to communicate well. I honestly suspect that they have changed the formulation of this pill. And it is frightening.

I was on Atenolol (25 mg) made by Mylan…but due to the so-called “shortage” was changed to Atenolol made by Zydus. I took “half” of my old Atenolol made by Mylan and half of the one made by Zydus…I got so sick, lightheaded/disoriented and had a hard time breathing. My pharmacy said it sounded like an allergic reaction. I then got a script for my Atenolol made by Teva and have had no problems. Why do we continue to get bad meds from India??? These generic drugs ARE NOT THE SAME AS THE NAME BRAND … when will the FDA get this?? These generic drugs can actually “kill” someone or cause a heart attach/stroke in some who aren’t getting the right dose of the meds! About time for a “lawsuit” …

I am taking atorvastatin. When I began getting my prescriptions at Walmart, I began suffering from severe itching.

India’s Aurobindo Pharmaceutical Generic Manufacturer, in my opinion, may have sold a very bad batch of Montelukast 10 mg through Costco, Park Meadows CO location in November, 2017. I started immediately feeling ill after refilling Rx 11.27.17 and have been in distress near to just over 30 days. I had successfully been on Camber Pharmaceutical’s 10 mg Montelukast for 3 months prior to this until Costco switched my Rx to manufacturer Aurobindo without my knowledge. Only after going back in records did I see that my November 27th refill had been changed to Montelukast Aurobindo from Camber Pharma Montelukast. I am now off Montelukast Aurobindo as of today, 1.5.2018 and I will see how I hopefully return to normal very soon. I will not restart any Montelukast until I can verify my suspicions re: Aurobindo Generic Montelukast 10 mg and will wait to make sure before returning to my trustworthy Camber Pharma original Rx 10 mg Montelukast.

Ranbaxy can’t even make decent soap. Lowila bar was made in the U.S for years, a very mild soap that worked for my extremely sensitive skin. Then Ranbaxy started making it and now it has such a strong chemical scent that I could smell it through packaging material from an online dug store. I threw it away and won’t buy it any more.

U do not even want to know what I think, it would not be allowed! This shortage of atenolol is a joke! But not funny to people who have been on it for fourty years! Just read a recall from Zydus, 30%atenolol, 20%some other drug! Really??? This is for your heart, not your toenail! I sent a copy of this report to the FDA, I have been in close contact with them for this shortage.

Did you know generic brands can have a choice of 1000 different fillers to use, told to me by pharmacist at FDA! This is utterly sick, and showing the uncontrollable mess they are in, and we are the lab rats! I went out of my network for 1 month to visit a very good cardiologist who is very seasoned, he advised me at this time to take the brand, tenormin. I do not care if it is an old drug, it works great on me, and why change it, oh! Iforgot about big pharma needing more
$. I can only take Sandoz generic, others will make my heart beat really hard, I will feel it in my temples throbbing…hey if we could send a rocket to the Moon many years ago, how come the FDA can not be CLEANED UP!

I’ve taken Lexapro for 14 years. Generic from Camber proved okay, but they sold out to an Indian company earlier this year. Without knowing this, I took the new generic for a few weeks. I started to get tired and nauseous, but it didn’t occur to me it might be medication related.

Then I started to get severe withdrawal symptoms-shaking, confusion, panic. I checked my prescription bottle to make sure I had the correct pills only to find the new manufacturer’s name. I immediately arranged to go back on the brand name. A week later I was feeling totally normal again. What a difference!

I developed tinnitus when I bought generic losartan from Walmart. This drug is manufactured in Croatia!

Oh my gosh. This sounds like me only with different drug. Please see my post above. I honestly thought I was going to die….literally. Something in the drug I was taking from India Aurobindo Pharm Manufacturer. Glad you are feeling much better. Hope I will be soon returning to my original Camber Pharmaceutical Montelukast 10 mg manufactured in NJ. Oh boy, just read that Aurobindo and Camber are owned by Dr. Reddy’s, Hetero? Have to research further. This is not good news to hear especially if they are producing dangerous generics in India and other plants outside of U.S. Feeling more distress now learning of more corruption greed and lack of care in the generic end of prescription drug manufacturing practices and standards.

I am taking Meloxicam and Hydrochlorothiazide made by Unichem which is a company in India. Are they safe to take?

The FDA is useless completely and thoroughly started this whole testing of generics subdivision. Yet, when you go to their own site everything that was tested (medications and products) listed passed! Regardless of type or amount of complaints they turned around and gave it the OK. I couldn’t find one medication that was turned in due to complaints that they didn’t end up passing with a satisfactory! And yet if you Google search and dig you can find recalls traced back to a section of the FDA listing some frightening examples and curiously medications that were complained about show up just in say different strengths or for reasons like torn packaging!?

FDA needs to take a look into CADUET generic from Dr.Reddy’s Lab, it is useless!

This is what I don’t understand they claim generics drugs are just as good as name brand as they contain the same ingredients of name brand if this is true then why do so many people get sick when they take people off name brand and put them on generic drugs I say when a company makes a drug that no other company can never make a generic of that drug the only company that should be able to make a generic of the drug is the company that made the name brand

Think I am having the third incident with Dr. Reddys out of India not being what it is supposed to be. Migrain for 3 days. BP out of control. Then I look on line and find that Amlodipine is one of the meds I take that Dr. Reddy is known for shorting in their mix. Time to talk to a lawer.

What’s sad is they are known for shorting medical medication? Who knows what’s in these pills. I used to buy generic Zantac from dollar tree. It was the only pill that cured my allergy in minutes. At some point they changed maker but kept the same packaging. The makers stamped on back were different. Dr reddy were unaffective. What’s sad is my elderly 87 grandma was relying on those and she noticed “they stopped working”. She has a cat in the house and can’t drive! Can you imagine? We have since bought generic at Walmart with sucess.

I refuse to accept generics from India or China and try to investigate any prescription’s origin I need before I pick it up.

I rarely take any medication but today stopped at CVS with a prescription for a sinus infection. I wasn’t feeling well and as usual, my prescription was handed to me all wrapped up hidden and stapled inside a bag with some forms attached outside.

It wasn’t until I returned home and opened the box that I discovered the z-pack was made in India despite me adding to the my record at the pharmacy I will not accept drugs from these countries.

It’s in the garbage along with the $10.00 copay for the 6 pills. I paid. I will wait and hope the infection resolves itself.

Here in MA we have access to only generics, by law, and CVS informed me most of their drugs come from India or China and they cannot get me anything else.

Many people I speak to locally tell me the drugs they are using don’t work and they usually end up going back for stronger or different drugs to resolve their issues. Could it be many of these generics are ineffective and we are throwing our money away? Is this all a scam?

Saving money is important but throwing away money on generics that do nothing or in some cases, cause harm, is criminal. Knowing the country of origin of anything we put into our bodies is basic information we are all entitled to and being made aware of recalls and drug manufacturing problems is critically important information affecting our health and safety.

I have to add another,I just remembered. My generic Zantac worked wonders and then it stopped working all of a sudden….so I checked the maker after the generic lunesta fake pill (that got me involved and up) and you guessed it…dr reddy was the maker of the generic Zantac that stopped working!! There is something wrong here!

This needs to be said. I spent a lot of money on generic lunesta made from dr reddy lab.
The pills are fraud! There was no effect, I’ve taken pills and accustomed to good or bad. This was neither. I’ve taken real lunesta from samples, so I couldn’t wait to take these. There is no pill there. I doubled the dose even, nothing, no effect. This is fraud. These pills are expensive. I’ve never had a zero effect from a pill before!

Lunesta from Dr Reddy’s lab is non-performing. I think this is the second time I have gotten a bad refill.

My Dad’s insurance changed to CVS Caremark first of 2015, and mid 2015 was his first order for Warfarin (4mg & 1mg). He has been on Wafarin for years and never had a problem.

After a few months of taking the new refill from the new Pharmaceutical company that Caremark used his INR started fluctuating, so the adjusting began, this was around mid November, took about 3 weeks and finally thought we had it right then BAM here it goes again and there was no getting it right this time.

So I looked who the manufacturer was, Zydus, and did research and found they were in India and the FDA has had many problems with them.

I also found complaints from other consumers on Warfarin made by Zydus.

I think as many problems as the FDA has found they should ban them completely and forever. I am having the Dr. write new prescriptions to a local Pharmacy that does not use generics made by Zydus.

My pharmacy changed to! Is this target? CVS bought targets pharmacy and my pills now feel like dissolved nothing.

Purchased some generic acetaminophen in 2015 and got a bad reaction. Researched the manufacturer and found out it was Sun. Reported this to FDA.

I have many examples: 1. my husband’s INR fluctuating widely after taking warfarin rather than the brand name Coumadin.
2. generic Lisinopril from Lupin was changed by CVS to another generic manufacturer and my BP was not well controlled.
3. giving patients generic Clonidine: two 0.1 mg tablets are now needed to bring down very high BP in clinic, whereas before only one was needed.
4. Apotex Atorvastatin caused me to cough and wheeze.

I take Losartan, the generic of Cozaar for blood pressure. I keep a record of daily blood pressure readings and it became clear that when I take the one manufactured by Torrent (India), it does not control my blood pressure. The readings are all over the place, like each pill has a different amount of effectiveness. But when I take the same generic made by Lupin (also India), my blood pressure is very well controlled and much better even-level low readings. My doctor has re-written my script to ask for the drug to be sourced from Lupin, but I am still uneasy if it can be trusted with the quality control issues coming from India in general.

Yes, I too am subjected to having medications swapped all the time…. what is unfortunate is that since my medications are for chronic pain, I am looked at like less than dirt. I have suffered with debilitating chronic back pain for years, as my spine has degenerated more and more. I also have no insurance to pay for medication, so I am forced to go with the lowest prices. My K-Mart pharmacy use to be great about ordering in certain brands of medication, not any longer. The new pharmacist refuses to do so. Sad, as I have shopped and spent a lot of money with them over the years. Now, they carry only Zydus, which is from India and gives me absolutely no relief! Worse, they don’t care!

I am a registered pharmacist and have worked in the generic and brand pharmaceutical industry for 31 years. I guess the rules for drug integrity have changed. I am presently working in a chain pharmacy and have seen drugs on the shelves coming from all over the world, why, because they are cheap and that’s what we want in this country. I have drugs from: Island of Malta, Slovenia, Croatia, India, China, Taiwan and Poland just to name a few.

It is a joke to believe that the FDA has been to these countries to truly perform inspections of the manufacturing plants.

Pharmaceutical companies moved production to India, China and other countries because of economic reasons due to the fact that there is no EPA, Osha, and minimal if any oversight from any government regulatory group.

If supermarkets are required to label fish, poultry, and meat as to country of origin, then prescription labels should also be required. This may help make the public aware of what is actually going on. The FDA is under staffed, overloaded and short on cash to do an effective job.

I sent the following email to Ms. Uhl. We all need to bombard her with emails like this. Shame on the FDA.


Ms. Uhl,

My insurance company CVS Caremark recently requested we save money by mail ordering the prescription Tamsulosin – 0.4mg Cap my husband was taking for his prostrate, which regrettably I agreed to. We noticed the mail prescription was made at Sun Pharmaceutical Industries as noted on the container and it was a different color. Within a few weeks of taking this drug, my husband was experiencing issues with not being able to urinate and was getting up several times a night. In the past we always got this prescription filled at Walgreens and NEVER had a problem withi it not working. After several phone calls and help from Walgreens we finally got a prescription and my husband noticed immediate relief.

This is a disgrace for the FDA to allow the drugs from India to be shipped to the USA without proper inspections to assure the drugs are made appropriately and are safe.

Luckily this is the only drug either of us take and the only reason my husband has to take this drug is due to 3 surgeries in one year due to doctor screw up.

Our FDA and medical system is a disgrace and has caused immense pain and hardship for our family.

Please do something about it NOW!

Thanks for listening.

Thanks for posting about problems with Sun Pharma’s tamsulosin. For 2016 I was switched to Caremark mail-order tamsulosin which turned out to be from Sun. After about 60 days and increasing heart discomfort, I experienced severe heart palpitations so I have just paid to switch back to the US-made generic tamsulosin I used to take…insurance isn’t covering it. The palpitations stopped 24 hours after the last dose of Sun Pharma’s tamsulosin. I will write to the FDA address you used describing my experience.

I agree, it is an outrage that these generics are made under such shoddy conditions. At age 59 I only take a few. Actually, I’m only taking Prevacid due to problems with generic. I was prescribed the generic to Flomax and a statin but they seemed to hit my system suddenly and caused lightheadedness et al…. They sit on the shelf and I take nothing at this time. I do also take a fiber supplement Metamucil. Some of these generics are ok but one was so bad it seemed to be made of sawdust and sand. I do believe the whole system is corrupt and part of the decline of this once great country.

It would help readers immensely if the PP had the Congressional subcommittee chairs identified. I just tried to find the committee with oversite of the FDA and it was impossible to extract. I’d contact Congress in a hurry with this issue. Can anyone provide this information?

How can we find out where our medications are made? And, how can we find a reputable Canadian Pharmacy if needed. It really makes me sick that our government doesn’t watch out for us. Let’s get back to things being made in the U.S.A.

It’s hard to believe that we are getting so many generic meds from China and India. Is there nothing we can do about it?

I have been prescribed Rantidine, a generic version of Zantac. My supplier is Walmart. When I read this article I questioned the pharmacist there. After some time he confirmed that Dr. Derry was the supplier. Usong this article as reference, I returned my current supply and got a refund. I then Checked out domestic sources anf found that SANDOZ makes in Colorado and several large box stores have that version. That’s my new source!
The pharmacists in both store said that without a batch number, they couldn’t comment.
So, rather safe than sorry, I’m sticking to the US producer.

I do NOT ever buy generics. I know most are not long release and have often less than 50% of main ingredient + cheap adjuvants. In hospital few years back they gave me generic anti-inflammatory within 4 hours I nearly died of asthma attack. My brother a scientist in Canada had my meds checked out in a lab. and found why – generics – bad news.

As is said: follow the money. The FDA receives much of its support from the very companies they are supposed to regulate. An open invitation for corruption. The pharmaceutical industry likes it this way. A lot of the name brand meds are formulated with products from abroad. Greed: more profit using cheaper materials.

Sometimes I feel as tho we the people are caught in a vise between greedy, and unscrupulous, corporations, corrupt, and bought, politicians, and all those employees who succumb to the lure of easy money – at the expense of the rest of us.

Thanks heavens for the internet thru which many of these schemes are brought to light. We have more information now, and more power, as people combining with people to effect change. I am 77, surely hope I see it before I go; I would like to see life change to being able to trust our food, trust our employers, work reasonable hours and use our our resources to make life better, healthier, happier for all people. Plus feel better myself.

What congressional agency oversees the FDA. They need to be warned about this. Of course Congress is part of the problem by not properly funding the agency. They also are probably receiving large campaign donations from these companies.

Several of my pills have changed color of the last few years. When I question pharmacy, I was told different company. I never knew so many drugs were made in other countries. Why not all made here. They charge an arm and a leg for so many, and they are made in other countries. The pharmacies are probably not paying that much and hiking the price for the consumer. Nothing we can do about it. I am on Medicare, so you know we get hit with some.

Wellbutrin XL 300 mg – was switched to the generic bupropion – horrible reactions. Insurance would no longer pay for Brand name. Fortunately found a reputable, licensed Canadian pharmacy – need a prescription just like in the U.S. – and now I am getting 90 Brand name tablets for way less than $200 which for me is a 3 month supply. It would be way over $1,000 if I had to pay out of pocket at a U. S. pharmacy. This pharmacy has been reliable and it is the same Brand name as I would get in the U. S.

I take sumatriptan for migraines. I ended up in the ER twice after taking sumatriptan for a migraine before realizing that my new prescription was from Dr Reddy’s. I filed a complaint with the FDA and make sure my pharmacies know not to give me anything from Dr Reddy’s.

I guess people will have to die before anything is done about the generic drug fiasco. Since it’s always about money, I suppose the mfgs. will always be outsourced but it’s the patients paying the price. Is there anything we can do aside from complaining – which accomplishes nothing?

Two years ago my pharmacy refilled Divalproex sodium ER sprinkles with Dr. Reddy’s version. Immediately I noticed a larger capsule and only about half of the sprinkles came out of the capsule. I contacted the pharmacy, Dr. Reddy’s, sent a sample, received an answer that there was no problem with the medication. I discontinued the med May 2015, now I wonder, are they denying a problem?

Dear Eileen,

I ran into the same problem when a brand name drug I took for a thyroid disorder was changed (without notifying me) to a generic made in India. I discovered that to meet our own FDA’s acceptable standards for the sale of a generic drug, all a pharma company has to do is include a minimum amount/percent of the main ingredient(s) which are used/included in the brand name version. I know so many people who have had bad/frightening/anxiety-provoking reactions when switched from the brand name drug to its foreign-made generic. All most doctors and pharmacists will say is “There is no difference between the generic and the brand name drug.” They are often WRONG when they rty to assure you that it’s “all in your head” when you say you are having bad side effects from the generic.
Would you please favor me with the name of the reputable, licensed Canadian pharmacy that sold you your brand name drug for much less money, as I, like you, cannot afford to pay out of pocket for my former thyroid med. Thank you so much, Eileen

I sent an email to the FDA as seen below:

I believe that the American public, using generic drugs, should be aware of what country their drugs are coming from.
I am a quadruple bypass patient, who takes 2 of the drugs, now in question: Amlodipine and Protonix.
I think that the country of origin, where these generic drugs are produced, should be on every patients prescription bottle.
Put yourself in my place. If you had heart surgery, wouldn’t you want to know that your drugs are full potency and safe, for you to take?
Thank you for reading my email.
Have a great day and continue working to keep us safe from unpure drugs
God bless you,

Does anybody see the connections between cutting the federal budget and the inability of federal inspectors to do a good job of enforcing good manufacturing practices?
Our representatives in Washington are always complaining of too much regulation and bloated bureaucracy.
Is the paucity of FDA inspectors in India and China an example of bloated bureaucracy and over regulation?

Last year my Dr. switched me from omeprazole to pantoprazole. It seemed to be working OK then last March my pharmacist changed manufacturers. I had been getting an orange pill and my new prescription was a pinkish mauve pill. The pink pill didn’t work at all. Medicare refused to pay for a replacement prescription. The consumer has no way to tell if the medication is going to be effective or harmful or if it is from an iffy manufacturer. I now insist on looking at my prescriptions before I will accept them. But… merely looking doesn’t guarantee that different manufacturers aren’t producing a medication that looks almost the same. The expense is borne by the consumer when the FDA and manufacturers don’t do what they are supposed to.

Penny, I concur with your email;
Three of my heart medications have changed size and color.
I called the pharmacy and they said, sometimes they update drugs and they are a different size and color. Baloney!
Some days I get very nauseous after I take my meds and I wonder if it’s the quality of the drugs I am taking.
Why can’t our American drug companies manufacture their drugs in the USA, instead of outsourcing them to foreign countries, so that they (the drug companies) can save money?
And then they charge us outrageous prices for these drugs.
Many senior citizens have to choose between buying healthy food and their drug costs.
People need to bombard the FDA with letters and emails about this problem, also writing to their Congressman.

We all (patients, doctors, pharmacists) know that generic drugs are problematic. Some of us have had negative experiences with generics, as I had with the Wellbutrin generic. It caused me to regress very quickly close to a suicidal state. That was years before the FDA acted, during which much ado with Medco, they gave special authorization so that I was able to get the brand, all the while as I was feeling suicidal. I continue to pay out of this world prices for it. But how I feel and react to a drug that is meant to help me deal with everyday, every hour and every minute of mental problems is so important that a generic that almost sent me to the padded room in less than a week is not worth the savings for the generic. Nobody should have to sacrifice by using the inferior drugs, no matter what the savings. It’s not worth jeopardizing one’s health for. And heaven knows what these foreigners put into the drugs as fillers. You could be ingesting melamine particles — remember the Chinese and their melamine in baby formula that killed a number of babies? You should not trust any foreign drugs or foods, and you should question it if you have a doubt. Don’t be poisoned by these substandard products. The generic Wellbutrin sent me downhill, but after much interaction with insurance, I am gettng brand name Wellbutrin — for a hefty price. I will not give in as long as I have money for brand although I have to give up other necessities. But I must submit that there are some generics that are of better quality, some by Eon, Teva, and other manufacturers. Thank you for listening. Do not give in.

Yes, I had the same experience. Also when I MADE myself take the generic well butron. I had this chemical taste and smell all accompinaid with depression, felt like a failure because it wouldn’t work!! Come to think about it. We are probably being terrorized. I’m not crazy! It’s so *great* to hears others come forward.

I filled a soma perscription and I was given drugs made by SUN PHARMACEUTICAL. I was sick and was in so much pain after taking it for 7 days that when I went to speak to the pharmacist about the obviously phony medication;I had to drive a wheel chair cart into Target. The could not refund my money or do anything to help me but they said I was not the only patient complaining. When it comes to pain medication you look like an addict if you complain that your generics don’t work the same. It’s very embarrassing. I know I’m Not a drug abuser and I know I’m not crazy. We should be able to get the info on generics!

Thank you for this information. I’ll check the ranitidine and amlodopine for the companies mentioned.

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