The People's Perspective on Medicine

Hawthorn

Hawthorn is a small thorny tree with white flowers and red berries that grows in England and throughout Europe. C. laevigata is only one species; related species have slightly different chemical profiles but similar medicinal uses.

Although hawthorn was known and used by the Greek physician Dioscorides, it became popular in Europe and the United States toward the end of the nineteenth century.

In countries such as Germany where doctors prescribe herbs and supervise their use, hawthorn is widely employed to treat angina and the early stages of congestive heart failure (New York Heart Association grades I and II).

In the United States, with herbs being utilized primarily as home remedies, hawthorn has been much less well known. Cardiac insufficiency of any degree is not generally considered amenable to hit-or-miss self-treatment, so anyone who chooses to use hawthorn should be monitored carefully.

The portions of the plant used are the leaves, flowers, and berries (haws), standardized for their procyanidin content.

Active Ingredients

Hawthorn flowers, leaves and berries contain from 1 to 3 percent of compounds called oligomeric procyanidins, also called pycnogenols or leucoanthocyanidins.

There are also flavonoids making up about 1 or 2 percent of the herb. The flowers and fruits are richest in total flavonoids and also contain the most hyperoside.

Leaves of C. monogyna also contain measurable amounts of vitexin-rhamnoside. Rutin, other flavonoids, and glycosylflavones are found in much smaller quantities.

Other components include purines, sterols, and amines, some of which may stimulate the heart. In addition, there are orientin glycosides, cyanogenetic glycosides, and saponins.

Uses of Hawthorn

Hawthorn dilates blood vessels. This activity helps lower blood pressure, and because it also dilates the coronary vessels, the likelihood of angina is reduced. It does not act quickly enough to be useful once an episode of angina has begun. A separate effect on the heart develops quite slowly, but is favorable, like a mild “heart tonic.”

Animal studies suggest that hawthorn extracts can also reduce cholesterol and triglyceride levels . It may also have a normalizing effect on blood sugar, although it is not considered appropriate for treating diabetes.

In Germany it is prescribed for certain irregular heart rhythms and is a component in some geriatric tonics intended for aging hearts that do not yet require digitalis.

Hawthorn extract inhibits thromboxane production (so it might be expected to reduce the risk of blood clots) and also has antioxidant properties.

Dose

The daily dose ranges from 160 mg to 900 mg of hawthorn extract, supplying from 4 to 20 mg of flavonoids (standardized) and 30 to 160 mg of oligomeric procyanidins.

The minimum daily dose should supply 5 mg of flavones (calculated as hyperoside), 10 mg of total flavonoids (again, calculated as hyperoside), or 5 mg of oligomeric procyanidins (calculated as epicatechin).

If the leaves and flowers themselves are used rather than a standardized extract, a tea is made by pouring 2/3 cup of boiling water over a teaspoonful of herb, steeping for twenty minutes, and straining. Two cups a day of such a tea constitutes a usual dose.

The dried herb must be stored in a tightly closed container away from light to preserve its potency.

A treatment period of six weeks is necessary to determine whether hawthorn is having the desired effect. The supervising physician should adjust the dosage as needed.

Special Precautions

There have been inadequate studies to establish that hawthorn is safe for pregnant and nursing mothers; indeed, the extract can reduce uterine tone and should be avoided during pregnancy.

People with serious heart problems and those on other heart or blood pressure medicines should consult their physicians before starting to take hawthorn.

People taking hawthorn must have their blood pressure and heart function monitored.

Adverse Effects

At normal doses, no side effects have been reported. At very high doses, animals become sedated, and people might experience symptoms of low blood pressure, such as dizziness.

Possible Interactions

Hawthorn extracts may increase the activity (but not necessarily the toxicity) of other cardiac tonics such as digitalis. It is not recommended for people whose heart condition is serious enough that they need Lanoxin or other digoxin medications.

Although no other interactions have been reported, prudence suggests caution if hawthorn is to be combined with other heart or blood pressure drugs (such as nitrates or calcium channel blockers).

Since hawthorn inhibits thromboxane synthesis, it may be incompatible with aspirin, which has a similar action. If hawthorn extract is taken together with anticoagulants such as Coumadin, careful monitoring of bleeding time (through PT and INR) is essential. Please discuss these possible interactions with your physician.

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About the Author
Joe Graedon is a pharmacologist who has dedicated his career to making drug information understandable to consumers. His best-selling book, The People’s Pharmacy, was published in 1976 and led to a syndicated newspaper column, syndicated public radio show and web site. In 2006, Long Island University awarded him an honorary doctorate as “one of the country's leading drug experts for the consumer.” .
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Do you have any references for hawthorn ‘reducing uterine tone?’ Why do you think it does this????

Hi, I have been taking standardized hawthorn (80mg) 6 times a day for my heart. I do take other meds as well, like 1x bumetanide 1mg, 2x metoprolol succ 47mg, 1x dabigatran 150mg, 1x digoxin250mcg, 1x cilazapril 5mg, 2x furosemide 40mg, per day.

I now have a new problem with my backside, having like muscle contractions, and it is very painful when I go to the loo for a #2.

This has started after taking hawthorn. I am a male 56yo still fit, my heart got hit with a virus. I must have picked up 30ys ago and it has hit my heart. Now, I have seen my GP about this matter. He is at a loss. My question is, would taking hawthorn have a side effect?

Cheers.

Sir, the problem is that the physicians do not know about herbs actions and normally they do not advise about their use. It is a pity therefore one needs to use herbalist guide who has knowledge of their effects and one has has to use one’s own knowledge to take herbs with combinations of drugs.

My view is if one does want to give it a try he should start herb with minimum doze and give a gap of at least 2 hours between the combination.

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