The People's Perspective on Medicine



Proscar is a unique compound that counters some of the negative effects of testosterone in the body.

It blocks an enzyme that converts testosterone to a more potent hormone called 5-alpha-dihydrotestosterone (DHT for short).

This testosterone derivative is apparently responsible in most cases for the gradual enlargement of the prostate gland that occurs as a man ages.

It may also have a role to play in male-pattern baldness.

Proscar is prescribed to treat the symptoms of benign prostatic hypertrophy (BPH–noncancerous enlargement of the prostate gland).

Although prostate tissue actually shrinks in most men who take Proscar, only about half or possibly fewer will get good relief from symptoms such as difficult urination.

A man must take Proscar for 6 months before the benefits of the medicine can be assessed.

Side Effects and Interactions

Proscar is usually very well tolerated and side effects are uncommon.

A few men have experienced impotence, lower sex drive or less ejaculate. Report any symptoms to your physician.

No significant drug interactions have shown up in the medical literature. As doctors and patients acquire more experience with Proscar, however, that may change.

Common sense would suggest that men taking Proscar, which acts in a similar manner to saw palmetto berry extract, should avoid the herbal product except under a physician’s recommendation and monitoring.

Check with your doctor and pharmacist to make sure Proscar is safe in combination with any other drugs you take.

Special Precautions

DHT is crucial for the normal development of a male fetus and is important in early male sexual development. Proscar should never be administered to children or women for this reason.

The manufacturer warns that pregnant women should not handle crushed Proscar tablets nor be exposed to the semen of a patient on Proscar to avoid possible harm to a male infant.

Because Proscar is relatively new, the long-term experience with it is limited. Periodic physical examination of the prostate is recommended for men on Proscar.

Taking the Medicine

Proscar is taken once a day with or without meals.

It should be stored at temperatures below 86 degrees F in a tightly closed container.

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About the Author
Joe Graedon is a pharmacologist who has dedicated his career to making drug information understandable to consumers. His best-selling book, The People’s Pharmacy, was published in 1976 and led to a syndicated newspaper column, syndicated public radio show and web site. In 2006, Long Island University awarded him an honorary doctorate as “one of the country's leading drug experts for the consumer.” .
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I have been taking PROSCAR, and now the generic, Finasteride, for 25 years! I am happy with the results. My prostate has been checked at least once a year and has not grown. In the beginning it was growing hence my doctor prescribed PROSCAR. After reading about the possibility that long term use of Finasteride may actually cause Prostate Cancer, I started doing some research.
According to my research, the results of various studies have shown different results. In 2008 there was a study which indicated that Finasteride could, in fact cause Prostate Cancer. Then the results were said to be erroneously interpreted. The fact was Finasteride actually helped prevent Prostate Cancer! Then in 2011, I read once again that Finasteride did actually prevent Prostate cancer. Can you tell me what the latest studies have revealed?

Proscar is causing breast tenderness, it started a few days after taking it. I have been taking it for the last 8 months. I am concerned if this will end in breast cancer, please advise me.
People’s Pharmacy Response: The risk of breast cancer while taking Proscar is very very low, but not zero. Here is a relevant study:

Recently I was prescribed Terbinafine & Finasteride, each for their prescribed uses.
I take each medication 1 hour apart, just my way of taking new drugs the 1st 30 day cycle.
Last night, (2nd day), following the same process, about 1.5hrs after taking the last of the two pills (Finasteride) I become extremely dizzy/lightheaded. Then it progressed to include wavy vision; with a feeling that the right side of my head was lighter than the other part, clear constant runny nose, dry heaves, tightness in my throat, and above normal blood pressure 149/90.
Many adverse symptoms cleared up after about 2 hours except the dizziness. This continued every time I opened my eyes and/or laid my head back.
About four hours from the initial onset, I was finally able to sit in a chair with my head and legs up to sleep.
This morning we are headed back to the Pharmacy to reverify the medications. Because the Finasteride was initially incorrectly filled with a pain killer – generic Percoset (oxy/cod …).
As with all new medications we initially verify the look and use online prior to taking the initial dose. This extra safety process has avoided now 4 incorrectly filled prescriptions in a little over 7 years. In this case it was blamed on the doctor’s poor handwriting.

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