Ceftin is a highly effective, broad-spectrum antibiotic that works against bacteria that cause a wide range of common problems.

This drug is especially beneficial for skin, ear and lung infections. It can help cure pneumonia, bronchitis, sinusitis and cystitis.

Ceftin belongs to a class of medicines called cephalosporins, which were originally discovered in one of the world’s most unlikely locations. A fungus found close to a sewer outlet along the coast of Sardinia turned out to cure a number of nasty infections. From this chance observation many extraordinary antibiotics have been developed.

Side Effects and Interactions

Side effects from cephalosporin antibiotics are generally mild. Nevertheless, diarrhea can be troubling for some people and in rare instances may develop into colitis.

Other reactions that have occasionally been reported with Ceftin include nausea, vomiting, vaginitis, itching, rash, stomachache, dizziness and headache.

If this medicine has to be taken for long periods of time, your physician will probably want to order periodic blood tests. Remember to report any symptoms or suspected side effects of this medication to your physician promptly.

Oral blood-thinners like Coumadin interact with medications related to Ceftin. Prudence suggests careful monitoring of bleeding time if these drugs must be taken together.

Special Precautions

If you are allergic to penicillin-type antibiotics, alert your physician immediately. Some people who are sensitive to penicillin may also react to Ceftin.

Symptoms such as breathing difficulty, wheezing, sneezing, hives, itching, and skin rash require immediate emergency treatment.

Life-threatening anaphylactic shock may produce an inability to breathe and cardiovascular collapse and can occur within minutes of exposure.

People with kidney or liver disease may need special medical supervision when they take Ceftin. This medicine may also interfere with certain diabetes tests.

Prolonged use of an antibiotic like Ceftin sometimes leads to an overgrowth of fungus or resistant bacteria known as superinfection. If this occurs, the doctor may need to have you discontinue Ceftin and take a different medication.

Taking the Medicine

Unlike many antibiotics, this medicine is gets into the blood stream more efficiently when it is taken with food. Although it can be swallowed on an empty stomach, we recommend taking Ceftin at mealtime to reduce stomach upset and enhance drug absorption.

Be sure to finish the entire prescription unless your doctor directs you to stop.

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  1. Kellie

    I’ve had great results with this. I had a chronic sinus, ear, and eye infection that was not going away after taking several types of antibiotics for about six months. I changed doctors and my new doctor prescribed me cefuroxime and clindamycin, and my infection is completely gone. It has been two months since I finished the antibiotics and there is no sign of infection. I am happy with it.

  2. Nancy

    I was prescribed this medication to take for 6 weeks for sinus problems. After taking
    for 4 weeks having a problem with being nauseated and the feeling that I am going to
    pass out that only lasts a few seconds at a time, but continues over and over. Having
    a lot of problem with gas. Noticing a few headaches. Going to call the Dr on Monday
    and let them know I am stopping the medication. Going to see if some other medication
    would be better for the sinus problems. Just can’t deal with feeling I am going to pass
    out any moment.

  3. emily

    I was given ceftin for bad tonsil infection (not Strep A, but, doctor believed it to be some form of strep)…I cannot take penicillin, amoxicillin, or the Z pak so he prescribed me ceftin. I was prescribed 250mgs twice a day for 10 days (though my doctor did say i could stop taking it after i felt better). I started taking it on sunday morning with probiotics. The first two days were ok, although my symptoms did not improve at all. The 3rd day my tonsils no longer had white patches anymore (though my throat was still swollen and sore) but I started getting very very naseated and dizzy, and extremely lethargic. I also got ulcers in my mouth and really bad sinus pressure and headaches. I stopped taking it and today is my second day without and I still feel awful….sinus pressure, lethargic, and naseas. UGH!

  4. pouneh h

    I took my Cefuroxime Axetil 500mg twice a day but at nights i can not sleep at all!!! before I had no sleep problem I’m very sleepy and tired and wish to sleep but my brain don’t want to sleep

  5. Carole

    My doctor prescribed cefuroxime tablets to treat Lyme Disease. I took them along with Doxycycline Hyclate tablets. About six weeks into taking them, I discovered that the cefuroxime tablets were being expelled whole. I dropped one into a glass of water. It took about 10 seconds to dissolve. However, I continued to expel them whole. Has anyone else had this happen?

  6. Karen B

    I was prescribed this 500 mg twice a day, first pill last night. I could not sleep due to my feet cramping so bad. Today I can barely walk and my feet feel like they are still in constant state of cramping? Is this normal>

    • Terry Graedon

      It might not be “normal,” Karen, but muscle cramps have been reported as a reaction.

  7. Jason
    New Hampshire

    I’m taking this medication for a combo of ear/sinus infection. I took the second pill a few hours ago. Woke up at midnight and almost choked to death in my sleep on saliva and bile. Ran to the bathroom and had an almost half hour cough/throw up fit. Finally stopped, was able to get my heart rate down. That was fucking terrifying. Not sure if just the drip from my nose unclogging mixed with the drug possibly disagreeing with my stomach is what set this off.
    All I know for certain is that right now I just want to sleep (been up cause of this illness for almost three days straight) but I’m far to scared to do so.

  8. Virginia

    prescribed cefuroxime axetil for acute bronchitis…took it for four days and had to stop. My mouth had a bad taste,headache and weakness…..having emphysema/bronchitis,the symptoms only got worse.

    There are too many dangerous and serious effects that this pill leads to. I am 85 yrs old and little problems, so why look for more!

  9. Aaron

    Has anyone else had foot after taking Certain? Thought I’ve been drinking enough water. Currently on day 1 with upper respiratory infection.

    • Aaron

      *Foot cramps

  10. Mark

    No issues with this drug or with taking it. No side effects at all. The Z-pak I had didn’t work and my conditioned worsened over that time. I got switched to this drug. It seems to be doing the job for removing bronchitis with two ear aches and a nasty sinus infection. I have 8 days left of it and any improvement is welcomed.

  11. Gabriel

    I visit the hospital today with my 6month year old kid and reported of phlegm/ sputum in faeces and chest area respectively and I was given cefuroxime axetil oral suspension but immediately he take it he vomits with much phlegm in the vomit please advise me

  12. marlene
    new york

    Ceftin helps my sinus infection but tastes bitter and gives me bad dreams but its not so bad. Some other drugs give me worse side effects so I will keep taking this for the ten days.

  13. Donna

    Cefuroxime (generic) 4th day, drained and fatigued. Upper chest and back areas (band) hurt from continued coughing. Decided to rub areas with Vicks for relief.

    Lots of draining with lots of snot….three boxes Kleenex gone. Stomach upset and cramping. Constipation though, not loose as was told would be.

    Have 5 more days of this hell. BTW….lost my voice after I stared this…still gone….

    Have decided to gargle with salt water. Guess it’s why they call it a practice…victims.

  14. Jon
    Bloomington, IN

    I was given some of this antibiotic by a friend because of an illness I had that included symptoms of sore throat (at the beginning), fatigue, slight fever, and headaches. I thought because I had recently quit smoking, the bad breath (at least to myself) and smell and taste in my mouth that I started experiencing after a few days was from that coupled with the sickness. Or I thought maybe it was from the Master Cleanses I was doing, or from any other number of things. After going through the list of what I’d been doing differently recently, I finally thought of the antibiotic. I looked it up and sure enough, that’s a side effect some people have reported. I forgot to take it in the evening yesterday and this morning I noticed the taste/odor wasn’t as bad. I figured I should finish the course of antibiotics and started taking it again this morning. It’s night now and the taste/smell is strong and awful again. Seriously the last several days have sucked and I’m pretty sure it’s because of this stuff! I will say though that I feel fine besides that though! Just fatigued! But man that taste is rank. I kept telling people it tasted smelled like an infection.

  15. Mel

    Took my first dose last night for a really bad toothache. 500g twice daily. I can honestly say that was the worst night of my life. When I wasn’t throwing up uncontrollably, I was writhing in pain because of the stomach cramps or rushing to the bathroom. Oh, and when the pain was bareable enough to try and sleep, my devil toothache kicked in. I would NEVER recommend this drug to anyone. Called my doctor and she told me to stop taking it immediately and put me on something more mild.

    • Gail

      Oh my. Your experience sounds exactly like mine. First pill taken last night. At 2:00AM I woke sipped some water, then seconds later I was scrambling for something in which to throw up. Had a quart ziplock bag. Heaved horribly, and eventually filled half full. Sweating so bad hair was soaked. Then diarrhea came same time as another round of vomiting returned.

      I barely made it to the bathroom. Heaved and threw up a lot in trash can. I was in this state of throwing up, diarrhea, and sweat for hours. What amazed me also about your post was your tooth ache. Haven’t had one in years and today I have a horrible ache in bottom molar or wisdom tooth. Do you think the medicine could cause the tooth ache? And I haven’t vomited in years!

      Also do you know how long it takes to get out of system? I am new to this state and Dr, pharmacist cannot answer how long it takes! I cannot find answer online. Any thoughts appreciated! I hope you are feeling better. I will never knowingly take this stuff again.

  16. nana ama

    Hi u guys got me frighten, I was just given cefuroxime axetil 500mg and with your comments am scared to take it.

    • regina

      Did you take it? Did you have any side effects? I was just prescribed this also.

      • Gail

        Don’t take it if you are elderly. Everyone is different, but it was horrible vomiting diarrhea sweating for hours for me.

  17. Gracie Ann C.

    My doctor prescribed Cefuroxime Axetil for my bacterial throat infection. Within 3 days I began to experience stomach aches and intestinal cramping. My symptoms worsened to include a very bad taste in my mouth, bad breath, a few mouth sores, frequent gas having a very offensive odor, loose stool with frequent bathroom trips, horribly painful reflux, and headaches. I was instructed to stop taking this antibiotic immediately. Yet, the next day, I had no bladder control with excruciating pain and had to go to the ER where I was diagnosed with a very bad urinary tract infection. This antibiotic must have masked the UTI. This was the worst experience I have ever had with an antibiotic.

  18. Stephanie

    I was prescribed this medication a month ago for bronchitis. I had chest congestion some aching and just feeling bad. I’m anemic so we tried cefuro x-men axetil 500mg 2x daily for 7 days. When my message were I took 1 the first evening and the next day on schedule. That was on Thursday by Saturday I was feeling awesome. I had energy and felt good, which I hadn’t felt in so long. It worked along with the prednisone.

  19. June
    New York

    I’ve been taking this for 3 days for a UTI and just took my last dose. Feel lethargic, but no other side effects. My concern is my symptoms (burning frequent urination) are still occurring. So, it doesn’t appear to be working. Not sure why they gave me a 3- day Rx. Also wondering was it less effective taking it on an empty stomach which I did several times since I had to set an alarm to take the first dose.

  20. Sue H.

    I’ve been taking this for 2 days. 500 mg 2× day. I get s.o.b. , stuffy head, and severely itchy inside my throat. Have a transplanted organ, I am allergic to penicillin. Reading this I think my dr may have over looked the allergy. Not going to take anymore, calling dr in the morning. At least I’m alive!!! Life is pretty good. Thank you.

  21. Alyssa

    This had caused my body to flare up and swell. My body tingled from head to toe and random numbness. 4 months later it has left me with muscle and joint pain along with nerve damage. I am just starting to get feeling back in my hands as they were numb due to swelling . This was a life changing and devastating experience.

  22. Jessica

    I’ve been taking 500 mg. twice a day. My issue is I’m pregnant and can’t eat for a few hours after waking up, and I have to take with food. It says to take every 12 hours. Basically I’m wondering if I can take it about every 10 hours since I am not awake by the time it has been 12 hours since my last dose. I’m afraid of overdose even though it’s only 2 hours earlier than when in supposed to.

  23. Jess
    Buffalo NY

    I was given Ceftin for a pretty nasty cellulitis infection. Received my first dose intravenously in the ER. Today I took my first 2 pills (500mg) and have already had one hell of a night. I woke up at 2am to my nose gushing clear fluid. I could taste the bitterness of the ceftin in the back of my throat, leading me to believe this was the culprit. Then I awoke at 4am because I had crapped my pants! Now it’s 5 am and I’m scared to go back to sleep, in fear of what I might wake up to next. I don’t know if I could handle 9 more days of this.

  24. Debra

    I’ve been taking this since yesterday and I’m having a lot of pain and soreness in my back, right shoulder, neck and head. I also am having pain in my right arm and now my hands are swelling, especially my right hand. Also sick to my stomach tonight. I’m really concerned. Does this medicine contain any sulpha?

    • PC

      Your joints might be getting affected. Stop it and Inform
      Your Doctor. Take lots of Probiotic.

  25. LS

    I have been prescribed 500 mg twice daily for acute sinusitis. Started taking it two days ago and my head congestion improved. I no longer am in serious pain with my sinuses. However, the cold appears to have migrated into more of a cough. I do feel improvement however — and this would be the very first antibiotic I’ve ever taken that actually helped my sinus problems. I had given up on them for years because the old school ones made me sick to my stomach while my sinus problems did not improve. This is a step in the right direction, I think. Although I wonder if I am taking too much of this stuff.

  26. Kate

    I was prescribed 500 mg 2x/day for acute bronchitis. I have taken 2 days worth and am feeling a bit better (fever gone, cough less, more energy, tachycardia gone) but everywhere I read that you need 250 mg 2x/day for acute bronchitis. Can I cut my pills in half and continue taking 250 mg 2x/day for the remaining 8 days instead?
    I am having slight side effects at the high dose that I’d rather not have – headache, dry mouth, a bit of nausea.

    • PC

      I think taking plenty of liquids, lot of Probiotic and taking the pill only after food and not on empty stomach might help. And some magnesium citrate to prevent muscle cramps might help.

  27. MeMe
    United States

    Started taking Cefuroxime Axetil May 20,2015, 50 g 2x a day for chronic sinus infection. …while I have noticed some improvement…..now I had the worst vaginal yeast infection (itching, soreness) and I have 8 more days on this medication….it’s good to have something to help with sinus symptoms. ….but then the medication causes another problem. ….would I take again…NO!!!

  28. littlepeaks
    Colorado Springs, CO

    I was prescribed this antibiotic plus another one for treatment of pneumonia. After receiving the drug for two days by infusion pump in a hospital, I took 500mg twice a day for 8 days.
    I experienced no side effects from the medication, except for a slight stomach upset sometimes. I have GERD, and this medication did not exacerbate that condition. The pills are large and chalky, and immediately start dissolving in your mouth, so you’d better be prepared to swallow that sucker immediately, unless you want to experience the bitter taste for a long period of time. This medication tastes bitter, like kale, except more intense. A swig of cough medicine with codeine wipes out any aftertaste. I have to give this medicine 5 stars, because it did help me get rid of pneumonia (whereas a different antibiotic was ineffective).

    • Gayle

      I took my Cefuroxime Axetil 500mg twice a day with some food in
      my mouth to swallow it with. Crackers, mashed potatoes, or any
      food that you can chew and keep in your mouth then put the pill in your
      mouth and it goes down with the taste of the food! I do that with all my

  29. barbie

    Oh my gosh, just took my 2nd pill, it was terrible. I eat my yogurt, then the pill I had wiped off and then more yogurt, lots of water. I still thought I would throw up, so glad I did not it must be terrible coming back up. I hope my doctor will give me a different pill today, I can’t take this for 10 days. What a taste, and why does it dissolve before it even goes down? So glad it was not just me that this happened to. Everyone be careful with this one.

  30. alf

    I was diagnosed with blighted ovum so d& c was done. After 2 days, I had a fever and severe cramping and back pain. I was prescribed cefuroxime axetil 2 x day.
    I went for an ultrasound and it was incomplete miscarriage. The performed another d & c and tubal ligation. I was given IV cefuroxime 750 mg for two doses. After 24 hours, I was discharged and was prescribed cefuroxime 500 mg 3 x a day.
    At first I did not feel bad side effect ts but after 2 days I experience mild headache, neck pain and stomach discomfort. My question is , is 500 mg 3 x a day not an overdose?
    People’s Pharmacy response: Please check with the prescriber. The usual dose is twice a day.

    • DEJI

      It should be 500 mg twice daily. Three times a day could be an overdose.

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