Cefadroxil (no longer available by brand name) belongs to a class of potent antibiotics called cephalosporins. This drug works against a wide variety of germs, including staphylococcus and Group A beta-hemolytic streptococcus. It is used to treat infections of the urinary tract, skin, throat and tonsils.

Cephalosporins are broad spectrum medicines that were originally discovered in one of the world's most unlikely locations.

A fungus found close to a sewer outlet along the coast of Sardinia turned out to cure a number of nasty infections. From this chance observation many extraordinary antibiotics have been developed.

Side Effects and Interactions

Side effects from cephalosporin-type antibiotics are generally mild. Nevertheless, cefadroxil can cause digestive tract discomfort, with diarrhea, nausea or vomiting. If you develop diarrhea contact your physician, as it may be a warning of drug-induced colitis (frequently caused by a disruption in the intestinal flora by Clostridium difficile).

Other common reactions include rash and itching. This should not be ignored, as it may be the first sign of a rare but very serious skin reaction [Stevens-Johnson syndrome or toxic epidermal necrolysis]. Swelling of the face and throat [angioedema or anaphylaxis] requires emergency attention.

Cefadroxil may raise liver enzymes and impede the flow of bile. It may also affect the blood and can trigger dangerous anemias. This medication has been known to cause seizures in some individuals.

Remember to report any symptoms or suspected side effects of cephalexin to your physician promptly.

Special Precautions

If you are allergic to penicillin-type antibiotics, alert your physician immediately. Some people who are sensitive to penicillin may also react to cephalosporins.

Symptoms such as breathing difficulty, wheezing, sneezing, hives, itching, and skin rash require immediate emergency treatment.

Life-threatening anaphylactic shock may produce an inability to breathe and cardiovascular collapse and can occur within minutes of exposure.

If you have reacted to another cephalosporin, such as Keflex, you should avoid cefadroxil.

People with kidney problems should receive cefadroxil only under strict medical supervision, as the dosage will most likely have to be modified to prevent toxicity.

Taking the Medicine

Cefadroxil may be taken with or without food. It may cause less stomach upset if taken with meals.

Get The Graedons' Favorite Home Remedies Health Guide for FREE

Join our daily email newsletter with breaking health news, prescription drug information, home remedies AND you'll get a copy of our brand new full-length health guide — for FREE!

  1. stan

    I have a bad skin wound doctor prescribed cefadroxil well since my knees both are been
    replaced they been hurting very much like a tooth infection I am giving different antibiotic my question is it making my knees hurt should I be taken my other also?
    People’s Pharmacy response: Please check with the doctor who prescribed the other antibiotic to see if you should be taking both.

  2. CSC

    I have also started having left side pain near the ribs and stomach a few days after beginning to take cefadroxil 500 mg twice per day.

  3. Aykan

    After I started I had abdominal pain and swollen left side under my stomach. I wonder if this is a side effect of cefadroxil 500mg?

What Do You Think?

We invite you to share your thoughts with others, but remember that our comment section is a public forum. Please do not use your full first and last name if you want to keep details of your medical history anonymous. A first name and last initial or a pseudonym is acceptable. Advice from other commenters on this website is not a substitute for medical attention. Do not stop any medicine without checking with the prescriber. Stopping medication suddenly could result in serious harm. We expect comments to be civil in tone and language. By commenting, you agree to abide by our commenting policy and website terms & conditions. Comments that do not follow these policies will not be posted. Learn how your comment data is processed.

Your cart

Shipping and discount codes are added at checkout.