Go Ad-Free
logoThe People's Perspective on Medicine

Will Sleep Deprivation Improve Your Mood?

For some people, sleep deprivation therapy may be an effective approach for treating severe depression. This seems counterintuitive, but data supports it.

This is a man-bites-dog story that you will probably have a hard time believing. It surprised us, that’s for sure. For years, all we have heard is that a good night’s sleep is essential for good health. If you don’t get adequate amounts of sleep, you risk developing hypertension, obesity, diabetes, heart disease, depression and possibly even dementia. But hold onto your hat. A new data analysis suggests that structured sleep deprivation can actually help lift depression.

Preventing Sleep to Counteract Depression:

Although chronic sleep loss is a problem, short-term sleep deprivation may be an effective anti-depressant for some people. A meta-analysis conducted by researchers at the University of Pennsylvania showed that both partial and total sleep deprivation could reverse depressive symptoms quickly for up to half the patients studied (Journal of Clinical Psychiatry, online Sept 19, 2017).

Partial sleep deprivation is effected by keeping people awake for 20 or 21 hours after just three to four hours of sleep. Total sleep deprivation requires people to stay awake for 36 hours straight. Both tactics appear to be equally effective.

Other Research on Sleep & Depression:

A study carried out in Italy on patients with bipolar disorder combined sleep deprivation, bright light therapy and lithium (Journal of Clinical Psychiatry, Feb. 2014).

The authors concluded that:

“The combination of total sleep deprivation, light therapy, and lithium is able to rapidly decrease depressive suicidality and prompt antidepressant response in drug-resistant depression in the course of bipolar disorder.”

Danish researchers have also reported benefit from what they call sleep abstinence, sleep stabilization or “wake therapy.” Such controlled intervention enhanced medication effectiveness (Danish Medical Journal, April, 2017).

Sleep Deprivation is NOT a DIY Project:

Wake therapy should not be done at home or on your own. A health professional who is experienced in this therapy should be overseeing it. The amount of time that a person receives wake therapy should be limited. Prolonged periods of inadequate sleep can have serious negative consequences, so it really requires a controlled clinical setting and lots of support.

Rate this article
star-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-empty
4.6- 21 ratings
About the Author
Joe Graedon is a pharmacologist who has dedicated his career to making drug information understandable to consumers. His best-selling book, The People’s Pharmacy, was published in 1976 and led to a syndicated newspaper column, syndicated public radio show and web site. In 2006, Long Island University awarded him an honorary doctorate as “one of the country's leading drug experts for the consumer.”.
Tired of the ads on our website?

Now you can browse our website completely ad-free for just $5 / month. Stay up to date on breaking health news and support our work without the distraction of advertisements.

Browse our website ad-free
Join over 150,000 Subscribers at The People's Pharmacy

We're empowering you to make wise decisions about your own health, by providing you with essential health information about both medical and alternative treatment options.