Illegible Rx

There was a time when a visit to the doctor’s office often resulted in a paper prescription that you would take to the pharmacy. Nowadays there is a strong likelihood that if you need a medication your physician will submit electronic prescriptions directly to the pharmacy of your choice.

Are We Becoming Too Dependent Upon Technology?

Computers, smart phones and electronic tablets have changed our lives. We rely upon these devices to tell us the weather, remind us of appointments and guide us through traffic.

Health professionals have also become dependent upon technology. This is especially true when it comes to writing and filling an electronic prescription.

Many physicians no longer write prescriptions by hand. Now they are selected and transmitted electronically to nursing stations and pharmacies. In theory this should make patients a lot safer.

No More Chicken Scratching:

For one thing, the illegible scrawl of years past is no longer causing mistakes. We’ll never forget the patient who was supposed to get medicine in his right ear (abbreviated R. ear). Instead the drops were administered rectally because the nurse misinterpreted the doctor’s handwriting.

We have seen prescriptions that would defy the most experienced hand writing expert to decipher. One of our all time favorites was published in the journal Pharmacy Times in 1977. It was written for the antibiotic erythromycin 250 mg. It came out looking like a bunch of es all squiggled together and a dose of 750 mg.

If the patient got the right medicine in the right amount it would have been a miracle. You can see it below along with another totally illegible prescription for Elixir of Pyribenzamine Expectorant with Ephedrine. We published these two examples of illegible prescriptions in our book, The People’s Pharmacy-2 (1980).

Illegible Rx

Illegible Prescription

Are Electronic Prescriptions the Answer?

Electronic prescribing has reduced such errors, but it has introduced others. Pull-down menus have led to dosing mistakes. One patient received a massive antibiotic overdose because of the complexity of the user interface.

What Happens When the Computer Cries Wolf?

Perhaps the biggest problems with electronic prescribing are the excessive alerts that come with each prescription. Doctors are warned about potential interactions with other drugs so frequently that many stop paying attention.

The same thing happens in the drug store. Pharmacists are also deluged with interaction alerts when they fill a prescription.

We originally assumed that computerized interaction warnings would prevent adverse drug reactions. Health professionals can’t keep all the dangerous combinations and permutations in their heads. That’s why computers could be so valuable in preventing risky mismatches.

Deadly Drug Interactions:

Like the boy who cried wolf, however, the computerized alerts have desensitized health professionals to some truly dangerous interactions. Research has shown that combining the antibiotic co-trimoxazole (Bactrim, Septra) with ACE inhibitor blood pressure medicine like lisinopril or ramipril may lead to sudden death (BMJ, Oct. 30, 2014).

This is the sort of interaction that could easily be overlooked by a busy clinician. Drug interaction programs consider this a relatively low-risk combination and tell prescribers to monitor potassium levels.

The trouble is that together these drugs can raise potassium levels so quickly that it could cause a fatal heart rhythm change. By the time a doctor arranges for a potassium test, the patient could already be in danger.

When Doctors Run Red Lights and Stop Signs:

We have likened ignoring drug interaction alerts to running red lights or not stopping at stop signs. The trouble is that patients are the ones at risk of an accident.

Patients need to realize that interaction warnings are routinely overridden by both physicians and pharmacists. This is a well kept secret, but ask drug safety experts who know a little something about electronic prescriptions and they will readily admit that this is an enormous problem.

Anyone who takes more than one medication should ask both the prescriber and the pharmacist to check for incompatibility. People should also follow Ronald Reagan’s motto: “Trust but verify.”

One way to do this is use an online service such as We also offer a free Drug Safety Questionnaire and Medical History form at Use this to get your health professionals to scrutinize your list of medications.

Electronic devices are convenient, but it is still essential to pay attention and use common sense. Most of us have had the experience of going in circles when the navigation system screws up. Let’s make sure we don’t put our lives in danger by trusting electronic prescriptions without double-checking them.

How To Protect Against Bad Drug Combinations:

If you find it hard to believe electronic prescriptions can be so dangerous, you will want to read the chapter titled “Drug Interactions Can Be Deadly” in our book, Top Screwups Doctors Make and How to Avoid Them. You will also find our “Top 11 Tips for Preventing Dangerous Drug Interactions” at the end of the chapter. Although there is much more information in the book, here are the headings:

  1. Take a list of all your medicines to your appointment.
  2. Find out how to take your medicine!
  3. Check about whether any foods or beverages should be avoided.
  4. Ask your doctor to check for interactions. Before you leave the office, verify that your physician has reviewed your entire list of drugs and dietary supplements to make sure there are no incompatible combinations. If your doctor is using a computer or handheld device to submit your prescription electronically, ask if there are any drug interaction alerts that you should know about.
  5. Ask your pharmacist to check for interactions. Do not grab and go when you pick up your prescription.
  6. Inquire about over- the- counter drugs.
  7. Go to the Web to check on interactions yourself. The best resource we know of is
  8. Don’t take herbs or dietary supplements without checking for interactions.
  9.  Beware drug-alcohol interactions.
  10. Inquire about drug-disease interactions. Some medications can make certain conditions worse.
  11. Check for prescription drug effects on laboratory test results. You will be surprised how many medications can alter lab results.

You will find far more information in the book. We also welcome your comments in the section below called “ADD MY THOUGHTS.” And please vote on this article at the top of the page.

Get The Graedons' Favorite Home Remedies Health Guide for FREE

Join our daily email newsletter with breaking health news, prescription drug information, home remedies AND you'll get a copy of our brand new full-length health guide — for FREE!

  1. EH

    Since the electronic medicine trend has started, I have noticed 2 serious issues. First I as the patient no longer see nor receive a copy (paper o electronic) of the prescription. It is sent electronically directly to the pharmacy. How can I check for errors or interactions when I cannot know what the doctor prescribed?

    Second, I no longer see nor receive a copy (paper or electronic) of the diagnosis, test results, etc. In my experience I do not know what tests, diagnosis, test results, lab results, etc were done nor what is in my medical records at each doctor office. Yes I have asked for them, and all but one doctor refused to share the info.
    Not only is it now impossible to know medical info about myself, but also impossible to compile an accurate medical history. Laws need to be passed for patient access.


    would like to receive comments by readers

What Do You Think?

We invite you to share your thoughts with others, but remember that our comment section is a public forum. Please do not use your full first and last name if you want to keep details of your medical history anonymous. A first name and last initial or a pseudonym is acceptable. Advice from other commenters on this website is not a substitute for medical attention. Do not stop any medicine without checking with the prescriber. Stopping medication suddenly could result in serious harm. We expect comments to be civil in tone and language. By commenting, you agree to abide by our commenting policy and website terms & conditions. Comments that do not follow these policies will not be posted. Learn how your comment data is processed.

Your cart

Shipping and discount codes are added at checkout.