an older man getting his eyes examined

Q. Do you have any information on the effect of Cymbalta on glaucoma? My doctor said that there was none, so I ordered $450 worth of Cymbalta. Three weeks later, my glaucoma pressure has increased 30 percent!

A. There is a clear warning in the prescribing information for duloxetine (Cymbalta) that it can worsen narrow-angle glaucoma. It should not be given to people whose glaucoma is uncontrolled and should be used only with great caution by those with controlled narrow-angle glaucoma.

Cymbalta is approved to help ease depression, anxiety, peripheral neuropathy, fibromyalgia and chronic musculoskeletal pain. There are other medications that could be used for these conditions.

You may want to check the official prescribing information yourself before you accept any other medications. It is available for most drugs at

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  1. Teresa S.

    I had uncontrolled glaucoma, more severe in my left eye which resulted in surgery for it. My glaucoma specialist said I have “open angle glaucoma”, the most common form. He indicated that taking Cymbalta would be okay with the type of glaucoma I have.

  2. Eyes
    Sun City, CA

    What I have been reading is people with Narrow Angle Glaucoma should not take Cymbalta. I called my eye doctor and was told I have Open Angle Glacoma, which she said was different. I am taking a low dose of Cymbalta and think I will continue until I see if my eye pressure changes with my next eye doctor visit. I am also going to keep researching to see if I can find out anything else.

  3. Kelly

    It was recommended to me but I’m afraid it might cause me more trouble with my glaucoma. I want to stop taking Norco for pain but meed a safe alternative.

  4. sharyn
    Pittsburgh, PA

    On Cymbala for 3/4 yrs. 1yr ago had cataracts removed – eye dr. told me I have glaucoma(mild) no treatments, just checkups. He did have my medications on my record. I’m now pretty unhappy to learn about interactions, etc.

  5. JeanneB

    I have been taking Cymbalta 60mg for a couple years now. Yesterday I was diagnosed with Glaucoma in my left eye & thinning in my right eye. I have no family history of glaucoma and it was a shock. I started using RX drops & have a follow up in 6 weeks.

    • sharon

      I’m on the same page as you. what have you found out? my eye doctor is keeping tabs on me. But now that I know that cymbalta may have cause this makes my anxieties go through the roof!

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