a bottle of PredniSONE 1mg, short-term steroid use, prednisone side effects

Prednisone can be a life saving drug. It saved my sanity when I developed sudden hearing loss in one ear. That was a really scary experience for someone who depends on hearing to be able to do live radio. Being deaf in one ear was incredibly disorienting.

The ear, nose and throat specialist diagnosed my deafness as “idiopathic sudden sensorineural hearing loss.” In other words, he didn’t have a clue what caused it. He prescribed high doses of prednisone for a short time and within a few days my hearing returned.

Other Corticosteroids:

There are a number of other medications that act in a similar manner to prednisone. They may be used in skin creams (topical preparations) or taken as pills. These include:

  • Cortisone
  • Dexamethasone
  • Hydrocortisone
  • Methylprednisolone
  • Prednisolone

All of these medications have different potencies, so they are prescribed at different doses. Even though they work in a similar way, they are not interchangeable.

Some steroid medicines such as fluticasone are designed primarily for inhalation or as eye drops. We are not discussing uses and side effects of those medications in this article.

As useful as corticosteroids can be for a wide range of conditions, the drugs can also cause an extraordinary number of serious side effects. Some people have likened such prednisone side effects to a deal with the devil. Even short-term use can cause problems for some people.

What Prednisone Treats:

Allergic Reactions:

One of the reasons prednisone and other corticosteroid drugs are prescribed fairly frequently is that their powerful anti-inflammatory action can be useful in many situations. These include very serious allergic reactions, such as serious poison ivy.

Another type of allergic reaction, to latex, peanuts, wasp stings, medication or other triggers, can result in anaphylactic shock. The immediate treatment is epinephrine. Prednisone or other steroids may be used to stabilize body systems after epinephrine opens the airways.

Neurological Inflammation:

Steroids such as prednisone are often used to reduce inflammation in brain or nerve tissue. This might be caused by a brain tumor or a traumatic brain injury. Prednisone can prevent brain swelling and the serious consequences that could result. Corticosteroid drugs may also help calm the inflammation of optic neuritis and multiple sclerosis.

Prednisone or another corticosteroid can prevent blindness when it is used to calm acute inflammation of blood vessels in the head, called giant cell arteritis. It can also reduce the swelling of the brain that may occur with altitude sickness.


In an acute asthma flare-up that can’t be controlled with the usual inhaled steroid or bronchodilator, prednisone can improve breathing. It reduces airway inflammation and can be very helpful in an emergency, though it is not appropriate as a standard asthma treatment.

Autoimmune Diseases:

Autoimmune conditions such as inflammatory bowel disease (also known as Crohn’s disease), lupus, polymyalgia rheumatica and rheumatoid arthritis can all cause severe pain and inflammation. Corticosteroids such as prednisone calm the hyperactive immune response as well as the inflammation. None of these steroid medications is a long-term solution, but they can get patients through difficult flare-ups.

Addison’s Disease:

In Addison’s disease, the adrenal cortex tissue that sits atop the kidney and produces the hormones cortisol and aldosterone fails. Frequently an autoimmune attack is the cause of the this condition, although infections can also trigger Addison’s disease. Secondary adrenal insufficiency can be one of the prednisone side effects that accompany long-term treatment for another condition. To treat this serious disorder, doctors prescribe hydrocortisone, cortisone or prednisone to replace the missing cortisol and fludrocortisone to replace the aldosterone.

Cancer Treatment:

Prednisone or other corticosteroids can be useful in treating a number of cancers such as leukemia, lymphoma or multiple myeloma. In addition to reducing inflammation due to the cancer itself, such medications may help lessen the likelihood of reactions to chemotherapy, including severe nausea caused by chemo.

Joe’s Personal Experience with Prednisone Side Effects:

Joe’s experience taking prednisone to reverse his acute hearing loss illustrates some of the prednisone side effects that other people may encounter. That week or two, he couldn’t sleep, became incredibly irritable and hard to live with, and felt as if he had turned into someone else he didn’t know or like.

His experience was not at all unique. A May, 2012, study in the American Journal of Psychiatry analyzed data from hundreds of thousands of European patients over an 18 year period.

They discovered that people taking corticosteroids were more likely to experience neuropsychiatric symptoms including depression, suicidal thoughts (and actions), delirium, disorientation, confusion, panic and manic episodes.

The authors conclude that:

“Glucocorticoids [another term for corticosteroids] increase the risk of suicidal behavior and neuropsychiatric disorders. Educating patients and their families about these adverse events and increasing primary care physicians’ awareness about their occurrence should facilitate early monitoring.”

Joe responds to this conclusion:

“I can relate. I certainly felt disoriented and out of control on the relatively high dose I was taking. The trouble is that patients and their families are not always warned about such side effects.”

We have heard from a surprising number of people that they were given very little information about prednisone side effects.

What Should You Know About Prednisone Side Effects?

There are some key questions you should ask whenever you are handed a prescription. You should know what the drug is and why you are taking it. Find out how to take it (how many times a day, with food or not, etc.) and how long to take it. Ask how to stop taking it, as that information is often left out of the discussion and it can be very important.

The most important information, however, is what side effects to expect. You have a right to know what side effects are most common. You might also want to ask about reactions that are rare but deserve immediate medical attention. This reader did not get any advance warning about prednisone side effects.

Surprised by Prednisone Side Effects:

Q. I was prescribed prednisone for sinusitis. It was a nightmare.

I gained weight and my face puffed up. I had strange dreams when I could sleep, which was rare. I became irritable and aggressive. Things that wouldn’t normally bother me made me want to scream.

I wish my doctor had warned me about these prednisone side effects in advance so I would have been better prepared.

A. Prednisone is a corticosteroid used to ease a variety of inflammatory conditions ranging from asthma and severe poison ivy to arthritis and lupus.

As useful as it can be for serious health conditions, there is a long list of troublesome side effects. Some of the most common include fluid retention (edema), insomnia, irritability, mood swings, disorientation, high blood pressure, loss of potassium, headache and swollen face.

Long-term complications may include muscle weakness, osteoporosis, cataracts, glaucoma and ulcers. Prescribers and pharmacist should warn patients what to expect in the way of prednisone side effects so they do not suffer in the dark as you did.

Steroid Psychosis from Prednisone Prescribed for Sinusitis:

Q. I am in very good health except for recurrent sinus infections. Recently, my internist put me on a 12-day tapered course of prednisone.

Within days I thought I was going crazy. I became extremely agitated and irritable and the least little thing set me off. I didn’t sleep for three days, even with sleeping pills. I couldn’t concentrate. My blood pressure soared and I became very fearful.

My doctor never warned me about any of this. Are these normal side effects of prednisone and what will I do if I have to take this drug again?

A. Prednisone and other corticosteroids (Medrol and Deltasone Dosepaks) relieve symptoms from a variety of conditions, including sinusitis. Many people experience severe psychological reactions to high doses of such drugs, however.

Steroid psychosis can cause anxiety, agitation, euphoria, insomnia, mood swings, personality changes and even serious depression. Some patients may experience memory problems or hallucinations.

Let your doctor know you are susceptible to this kind of reaction. If you ever have to take more than 40 mg of prednisone at a time, you may need medication to counteract the psychiatric side effects.

Scary Prednisone Side Effects that Have Been Reported to Us:

A.C. shared this story:

“Years ago I was given prednisone in the emergency room for a severe anaphylactic reaction that affected my ability to breathe and caused massive hives. Although the treatment may have been necessary, I too had a severe psychotic reaction and when I finally went to my own doctor and had blood tests, my blood chemistry was all over the map. I had to continue the tapered dose till I was done but I wish someone had warned me of possible side effects so at least I wouldn’t think I was totally crazy.

“I questioned my ability to drive, slept constantly and was quite volatile. I had to take a day off from work. Knowledge is power! People should be warned about possible side effects so they have the information should prednisone side effects occur.”

When people are unprepared for the psychological side effects of prednisone, they can be caught off guard. So can family, friends and co-workers. In A.C.’s case, the prednisone was was essential for survival. That said, A.C. should have been alerted to possible side effects.

As we mentioned earlier, corticosteroids are essential drugs for many conditions. A severe asthma attack may require a short course of oral prednisone or a similar steroid. People who are put on the new immunotherapy checkpoint inhibitors against cancer such as Keytruda or Opdivo may experience an overactive immune system. That can result in skin rash and itching, severe diarrhea and colitis, hepatitis, pneumonitis, adrenal insufficiency, eye inflammation and neurotoxicity. High doses of corticosteroids may be required to counteract such reactions to the cancer medications. Even then, people must be warned about complications.

Ely describes what happened after a moderate dose of prednisone:

“I’m having prednisone side effects. My doctor prescribed this drug last Thursday. She prescribed 20 mg twice daily for five days. I was sleepless for three days in row. On day 4 after a short nap I awake feeling so nervous. I am crying, my hands are shaking, and my heart is beating so hard. These are awful feelings.

“My doctor told me I will feel that way for about nine days. She didn’t show any care about me. She also said I can go back to work (and drive a long way) the next day. But the way I was and am feeling, I’m not daring to drive even one block.

“I do not understand why she prescribed that medicine, without any warning, for a small allergy I had. I mean the medicine was worse than my illness.”

Bob describes what it’s like to be sleepless on steroids:

“My wife had sleepless nights when on prednisone and the doctor said that she might do some odd things that she normally wouldn’t do. He was right. One night she got up and tore down the wall paper in our bathroom :-) We still get a laugh over this one.”

How to Stop Prednisone:

We may have mentioned that when steroids are taken even for a short time, such as a week or ten days, the usual protocol is to start at a relatively high dose and then taper it down gradually. That reduces the risk of an unpleasant withdrawal reaction. Always ask the prescriber about the taper and follow the instructions.

A.M.S was not told how to stop steroids:

“I was on 20 mg twice a day of prednisone for a sinus infection. Had I known anything about this horrible drug, I would have never taken the meds and let my sinus infection clear up on its own. That would have been better than these prednisone side effects.

“I was not told to taper the dose, so I took as prescribed 20 mg twice daily for 7 days. The day after stopping, my whole body hurt to the touch, as if I was black and blue all over. I was swollen, red and had a lump on my neck, not to mention being very disoriented. I went back to the doctor and he insisted this had nothing to do with the drug.

“I checked myself into the ER where they put an IV drip with Benadryl and the like. I was discharged that day. No change. Next day, didn’t hurt to the touch anymore. New side effect – rash from head to toe and severe indigestion. Following day, rash subsiding, indigestion getting better. Still feeling a bit loopy, but I am told by next week I should be back to myself again.

“I am warning everyone I know not to ever take a steroid unless your life is in danger. It is a very scary feeling – all for a sinus infection.”

S.K.F. describes prednisone withdrawal:

“I am experiencing high blood pressure, agoraphobia, panic attacks, lightheadedness, confusion, weakness, intolerance to heat, IBS, shaking, etc. These side effects all started the day I stopped the drug. It has been 7 days with not much improvement. I was hospitalized for 3 days. I pray I do not EVER have to take prednisone again… EVER.

“I am hoping I get past this. My quality of life stinks. I took 30 mg 1 day 20 mg 2 days and 1 mg 2 days. Absolutely HATE this.

Just the Tip of the Corticosteroid Iceberg:

These are just a few of the messages that have been posted to our website. At last count there were over 800 comments in the feedback section of this post. Feel free to add your story or comment below.

We find it astonishing that some prescribers do not warn patients about the possibility of psychological side effects brought on by prednisone and friends. Even a short-course of high-dose steroid can precipitate symptoms. And not telling patients about gradual tapering borders on bad medicine. To protect yourself and your loved ones from such medical mistakes we suggest our latest book, Top Screw-ups Doctors Make and How to Avoid Them.

Psychological reactions such as insomnia and irritability are common, but they are certainly not the only prednisone side effects. Some of these adverse consequences, such as osteopenia, diabetes or glaucoma, appear only after long-term use of the drug. Others, such as confusion, high blood pressure or a drop in potassium, can occur on a shorter time frame. The most serious prednisone side effects that may happen within a week or two of use are dangerous blood clots (deep vein thrombosis), blood

Other Prednisone Side Effects:

  • Fluid retention, edema
  • Insomnia
  • Irritability, nervousness, mood swings, mania, depression, psychosis
  • Disorientation, confusion
  • Hypertension
  • Loss of potassium
  • Headache
  • Dizziness, vertigo
  • Muscle weakness
  • Blood sugar elevation (diabetes)
  • Irregular menstrual cycles
  • Swollen face
  • Hair growth (including on the face)
  • Itching, rash, hives
  • Increased susceptibility to infection
  • Weakened bones (osteopenia, osteoporosis)
  • Tendon rupture
  • Glaucoma
  • Cataracts
  • Ulcers
  • Deep vein thrombosis (blood clot)
  • Avascular necrosis of the hip

The higher the dose and the longer someone takes a drug like prednisone, the more likely there will be prednisone side effects. A recent study of people with steroid-dependent asthma reported that the majority of patients who had been taking prednisone for years experienced side effects such as bone density loss (72%), high blood pressure (60%), cataracts (42%), easy bruising (35%), diabetes (16%) and glaucoma (14%) (Aziz-Ur-Rehman et al, Allergy, Asthma and Clinical Immunology, online April 4, 2017).

The People’s Pharmacy Perspective:

Make sure your physician is monitoring things like potassium, blood sugar, bone density and psychological well being. And again, never stop a corticosteroid suddenly!

We want to emphasize that corticosteroids can be very valuable. Some people must take them for the rest of their lives because of a very serious or life-threatening condition. And NO ONE should ever stop taking a drug like prednisone suddenly. It must be phased off gradually under medical supervision.

If you found this article of value, please take 3 seconds to scroll to the top of the page and vote on the usefulness of this information. Many thanks from The People’s Pharmacy.

Revised: 4/28/17

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  1. Linda

    My story is just a little more odd than most I have read because I was given only 2 mg of prednisone to try to control pain joint pain that i am still working with my doc to find an answer to. I made a point of telling him that I am extremely sensitive to all medications and that baby doses are all I will ever consider of any drug. The pain became unbearable. He put me on a 2 mg dose for three days, with a very long slow taper. After day two, I found myself writing emails to family members telling them I hated them, I told my best friend I would be unavailable for the next few months. I am quite literally going insane. Now to top that off, the pain is far, far, far worse than it was just 2 days ago. I cannot put any weight on my wrists without screaming in pain. I have welts on my shins. I have a headache that would kill a horse. The bottom half of my vision is simply gone. My neck is stiff. My hands and feet feel like they are on fire, my face is hot to the touch. I’m afraid to move and am certainly afraid to interact with anybody as my level of rage is in uncharted territories. I have no appetite. I have a sore throat and swollen glands. I am exhausted yet shaking from the inside out in a way I can’t even describe. TWO MILLIGRAMS. TWO. Absolutely the worst medication I have ever experienced and now I have to go through a taper of it on top of that because going cold turkey is worse? Wow. Unless your life absolutely depends on this medication stay as far away from this devil as you can. And yes, I am suicidal as well. From 2 milligrams. Oh did I mention the uncontrolled crying jags? Stay far away unless this drug is your ONLY life saving option.

  2. Tatiana
    United States

    I’m currently taking Prednisone- 2 tablets a day for 5 days because of a sudden asthma attack. The last time I had the same dose and medication was last year for an acute bout of an ear infection. And, both times prescribed, my hearing has gone off-key to a lower key. So, music and sounds are a note deeper than they should be and for me, it’s very disorienting. I hate the stuff. I even fretted about the medication in the doctor’s office yesterday but my doctor and the pharmacist were adamant about me using it. Can’t mankind make something that doesn’t affect the senses so dramatically???

  3. RON

    Have been on methylprednisolone 4 mg for 4 years and now have full blown cataracts and glaucoma. I have been telling my doc for the last 2 years that my eyes are getting fogged, and he said well we will cut it down a bit. Never said that this could happen. Can hardly see anything. Need surgery and laser surgery.

  4. Amber
    New York

    I was diagnosed with pneumonia 8 days ago and started antibiotics the same day. Was told it most likely would take anywhere from weeks to months to feel completely healed but that the cough and trouble breathing should start getting better after 1-3 days on antibiotics. 2 days ago my cough got worse and my chest hurt when breathing, I’d get winded just walking and I had a headache. Later that night I started getting chills, dizziness and my temp went from 102.6-104.3 in 2 hrs and while on Tylenol and ibuprofen. My husband called an ambulance after I lost consciousness due to not being able to breathe well… was in the ER for 24 hrs, they gave me IV fluids/antibiotics and my first dose of prednisone an hour before discharge, with a 10 day script of 50mg daily and some breathing treatments.. last night I couldn’t fall asleep even tho I was exhausted from barely sleeping at hospital, my heart was racing but my fever had spiked again so I thought it was that until I looked up prednisone side effects.. I’ve had no appetite today and felt really off, nausea started 2 hrs after taking morning dose and it’s got worse to where if I stand up I gag or puke. After reading this article and comments, I don’t even want to continue the course of this drug! I’m a young mom of 3 young kids and I babysit during the week so I need to be healthy yes but the side effects listed are awful! Most likely going to start tapering bc the ER dr didn’t only fail to tell me about side effects, but didn’t mention withdrawals or recommend tapering. I’ll just pray the antibiotics and breathing treatments clear my chest… I don’t need to add issues bc of this ridiculous drug.

  5. Tena

    I’m having a difficult time imagining why my doctor prescribed 60mg of prednisone for me to take three days in a row. I’m 4’ 11” and was in the ER last night from the side effects. I didn’t take any today, but I’m flushed, anxious, feels like my BP is high.

    All I needed was something for an allergic reaction to insect bites.

    I’m going to Walgreens to have my BP checked.

  6. Omar

    I use this medicine to treat sinusitis and not cure it. I was on the verge of death because this medicine suppresses your own immune system, so its kill you slowly. Thaks to God that im intelligent and stop using it and begin to drink natural veggies and fruits juices to heal my inmune system again.

  7. Nancy
    Waukesha, Wi

    I was prescribed 6 tapers of Prednisone back to back over 7 weeks. Not once when I picked up any of these 6 prescriptions was I warned about the adverse side effects of taking Prednisone. Let me put this in context to outline the seriousness of my adverse side effects. When I say adverse side effects I am referring to hostility, aggression, rage, being set off by things that never bothered me before. Just over 3 months ago I started a new job with a local church.

    Doing the math you can see that for half my time at my new job I was on Prednisone. I knew I felt differently. I knew I was full of rage. I had trouble interacting with people EVERYWHERE! What is deeply concerning to me is the sit down talk I had with the pastor and the president of the common council last week. I was informed that members of the congregation had been discussing my rude aggressive behavior with the pastor and council President as well as amongst themselves.

    Embarrassed and full of shame doesn’t begin to describe how awful I feel. I feel that Prednisone single handily derailed my job. To say that my job was my life is an understatement. It meant everything to me. I was thrilled that I was attending worship services on a regular basis. I was thrilled to meet such wonderful people. Since my sit down with the pastor and the council President everything has changed. I don’t want to show my face. There isn’t a hole deep enough for me to crawl into. Since I got home from work Friday, I have not left my house. I can’t even go to the grocery store.

    Taking Prednisone for such a long time has completely derailed my job. It has been a huge nightmare. I don’t know if I will ever be able to recover from this nightmare. It’s a damn shame I didn’t listen to myself when I knew I felt so aggressive and hostile and full of rage. To anyone reading this, let my story be a lesson , DO NOT EVER TAKE PREDNISONE! It is a nightmare.

  8. Laurie
    Redmond, Washington

    In case you want to know about insomnia and prednisone, my son was given the drug for an ordinary sinus infection at 60 MG. at a walk-in clinic. After only one dose of 60 MG. he had a horrible reaction, racing heartbeat, anxiety, and sleeplessness. After an entire week he still struggles to get even 4 hours of sleep. Thankfully, the other symptoms are dissipating but the insomnia is still a problem. All this for a single dose of 60mg. The worst is that the doctor didn’t bother to fill him in on the side effects so he wasn’t able to consider not risking them. So much for trusting a doctor.

    • Omar

      I use this medicine to treat sinusitis and not cure it. I was on the verge of death because this medicine suppresses your own immune system, so its kill you slowly. Thaks to God that im intelligent and stop using it and begin to drink natural veggies and fruits juices to heal my inmune system again.

  9. Stacy

    I was diagnosed with Crohn’s Disease in 1997 so I’ve been on my share of Prednisone. But, all but one GI doctor tried to keep my doses low and taken as little as possible. The GI doc I had was off for some reason. I wasn’t flaring too badly but while in the hospital, I was put on a heavy dose of I.V. steroids. So, I couldn’t just go home and take a much smaller dosage.
    The doctor who saw me in the hospital put me on 80 mgs. of Prednisone a day.

    I had to taper off weekly. 80 for a week, 70 a week and so on.
    I even told my mom that I felt that I was on way too much. But, I knew better than to go cold turkey it. The only side effect was weight gain. But, I gained 100 lbs. I’ve never been overweight in my entire life until Prednisone entered my life. My GI did do a bone density test, and it was normal. In fact, everything was. Normal A1C, BP, no mental problems, nothing.

    In 2009, I stopped the IBD maintenance meds. Doctors can’t find the disease anymore. It’s like it just decided to die off, thank God. I still never have any IBD ever. Fast forward to 2014. I’ve been having stiffness in my back and neck. My GP would give me steroid shots. They worked at first.
    Then, I would be startled awake with these terrible back spasms. They happened every 10 minutes or so. I didn’t get to sleep until 8 the next morning. So, I was put on Tramadol and Baclofen.

    Now, in 2017, I can barely turn my neck from side to side; the muscles in my back and neck are always tight. There’s hardly any give to them. It is so bad that I couldn’t turn my neck when I was turning the corner in a parking garage and dented the truck. Last week, I was walking to the truck after shopping. I was stooping over a bit. Plus, the sun was in my eyes. By the time I managed to look up. I didn’t see a thick square of wood sticking out of someone’s truck. I slammed into it with my left cheek. It knocked off my glasses and badly scratched my cheek. It’s healed great now but you can see how badly my disability has affected me.

    I’m still on Tramadol and Baclofen. But, I also have to take Goody’s or BC powder for Arthritis if I want to be able to bend down to tie my shoes.
    The aspirin with the pain meds and muscle relaxants really help.
    My brother is a massage therapist so that helps.

    But, is there anything that I can do to get my range of motion back without needing all these meds? I’m tired of having my neck and back muscles feel like they are set in stone. Taking more steroid shots isn’t an option for me. I want to try to avoid them as much as possible now.

    I’m 41. I want to feel as normal as possible before I get too old to enjoy my favorite activities, which are hiking, exercising, biking and other things. I’m an outdoor person. But, ever since 2014, I stay home more and more. I even avoid shopping a lot.

    What can I do? I feel too young to stop living the way I want to.

  10. Cher
    Wayland, NY

    I developed a cold sore and I actually thought it was acne. Just one sore by my lip, covered it with Clearasil and a Band-Aid. Woke up three days before Christmas 2016 with a swollen eye, saw pa said I had pink eye. Christmas mooring my eye was worse, went to regional health, same diagnosis but they changed me for drops to ointment.

    Did not improve so I went to my eye surgeon and he said I had uveitis and gave me durezol. New super strength steroid eye drop. Ended up going to fkaum eye institute, had herpes simplex eye infection from cold sore virus. Am now taking at least 6 .05 Xanax to deal with the damage to my system and anxiety.

    Now, on weaker eye drop but no dr will admit that durezol caused anxiety. Emailed a friend of my daughter’s, top eye surgeon John’s Hopkins who told me that some of her patients have had the same experience as I am having. Just a warning and I am still suffering after 10 months. It does happen to some people.

  11. Linda

    I have severe asthma and I have found prednisone to be very helpful and have never experienced adverse side effects. I have felt better and had more energy and life seemed worth living again. I am sorry for all of those people who had such awful side effects. I pray I never have them because I have no choice but to use prednisone.

  12. Richard
    British Columbia

    My aunt was prescribed prednisone for asthma when she was admitted to hospital. After 3 days, she started talking with a grandiose air and making extravagant purchases and plans. She started writing a book and was going to direct a play that was to take place in a neighbouring bandshell. She wrote day and night and called people at inappropriate times. She was forced off the drugs. She had no idea anything was wrong with her. The behaviour continued for 2 months after the prednisone was stopped, and then she had a huge melt down and completely lost her mind. An ambulance was called, and she was hospitalized for a day and surprisingly released. She was quiet for 6 months, but for the past year and a half has been condescending, aggressive, intense, no empathy, grandiose, queenly, opinionated, interrupts others, and has become punishing and mean. She has no filter, and can’t tell if what she is saying is hurting or offending people. She still continues to work part-time in a retail store and hasn’t been fired.

    Is this a documented pathology where prednisone can cause long-term, chronic, lifelong personality disorder? She seems to be manic too.

  13. Babs

    I am on a 12 day regime of prednisone with the first 6 days 60mg per day and the remaining to be used to taper off the drug. I’m on day 3. I have had no side effects following instructions to take med in am and with food.

    The ringing in my ears has no change and the lump in the left lingual side of my tongue has not reduced. When should I expect any changes?

  14. David
    Sonaran Desert

    I was given Prednisone Intermuscular when admitted to the ER for an anaphylactic reaction to a Bee sting. I had already given myself a dose of Epinepherine (Epi-Pen) as I am supposed to, and that had brought the anaphylactic reaction under control, long before the EMT’s arrived. Upon release from the ER I was perscribed Prednisone oral 10mg BID for 5 days, this is day one. I was admited to the ER 26 hours ago, and released 20 hours ago.

    So far as to reactions to prednisone, I have vomited 3 times (I had never in my life vomited in memory before), ejecting whatever portion of the drug had not yet been absorbed, along with my keppra (I experience epeliptic seizures, fairly regularly normally, keppra helps to control this), and any food in my stomach. I have not been able to sleep, I have felt very hot on this very cool 90 degree day (cool for here, sanoran desert).

    I have further had both surface sensations on skin, and stomach feelings that are beyond my ability to describe, as they are so different from anything I have ever previously experienced that I have no reference to be able to put these sensations into words. These sensations are very very unplesent.

    I am having ghost sensations in my legs/feet. While I do have some sensation in my legs (paraplegic) these sensations are much stronger than what I capable of feeling in my legs/feet. Sensations as strong as what I can feel in my arms, and uncomfortable sensations at that.

    I also experienced a strong sense of all is well for a few hours that I can only attribute to a potential psych reaction to Prednisone.

    I read that Prednisone increases the risk of epelictic seizures, beings as I normally deal with reasonably frequent epelictic seizures this scares me a bit, especially as I am not able to keep my Keppra down, do to the prednisone causing me to vomit.

    As the use of epeniphrine had brought the anaphylaptic reaction under control, and there was no sign of the symptoms returning, I do not understand whay the ER physition chose to perscribe Prednisone. I could understand possibly perscribing an antihistamine or histamine-blocker, and monitoring for me for an extra couple of hours to be safe, though prednisone is a definite case of overkill qubed (raised to the power of 3) for this case.

    I belive that the level of negitive effects I am experiencing qualify as an elergic reaction, as they are worse than what would call for an ER visit if they were from any other class of medication, as such I am discontinuing the Prednisone, calling this evenings dose the final dose. If it is that the withdraw side effects turn out to be as bad as is often reported, after only three doses then I will have to deal with that in the best maner I am able to .

  15. Gary

    I was prescribed Prednisone when I developed an unknown rash and itching. After numerous tests the cause was undetermined and I was put on Prednisone usually between 5mg and 10mg. I have been on them now for about 7 years and my arms are starting to show a lot of skin deterioration. My doctor wants to reduce gradually my daily intake to 5mg through 1mg reductions for 4 weeks. After four days the itching has returned to the arms and torso. I want to know what other body parts that Prednisone affects if taken long term.

    • Billy

      Do you consume anything that contains artificial sweeteners?
      Protein drinks, diet soda and anything of that nature?
      I had an unbearable, undiagnosable rash for 4 years. It was from the artificial sweetener in Muscle Milk, a protein drink that contained no sugar.
      I stopped artificial sugar and the rash is gone!!

  16. PS
    New Jersey

    Very helpful article.

    • MarieLouise
      New Zealand

      I went to see my GP for a doctor’s certificate to take 2 days off from work due to a persistent cough (I am nurse and could not work around patients like this). I also had a sore throat which was getting better and wasn’t really bothering me anymore. My GP decided to give me Prednisone 40mg per day for 5 days. That was on a Tuesday morning. As soon as I got home i took the first dose of Prednisone. That night I woke up around 03h00 with the most painful throat I have ever had. By Thursday night I could hardly swallow my saliva let alone any food or drink. I looked up the side effects and saw that you have to let your doctor know if you have a persistent sore throat. I did not take the rest of the tablets and am now waiting to see if things are going to clear up over the next 7 days. Good luck to me.

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