Q. My doctor has me taking an ACE inhibitor blood pressure medication called lisinopril and an ARB called Diovan (valsartan). These drugs make me dizzy and sap my energy. I have headaches, heart palpitations and gastro-intestinal problems. Whenever I complain I am pretty much told to suck it up and that my symptoms are all in my head.
At my last doctor’s visit my blood pressure was 140/90. Instead of getting an “attaboy” and congratulated, I was told to up the dosage.
A. Yikes! The very first question to ask your doctor is whether it is appropriate to combine lisinopril (and ACE inhibitor) with valsartan (Diovan) which is an ARB (angiotensin receptor blocker). A Canadian study found that combining ACE inhibitors with ARBs increased the risk of kidney damage and potassium overload, especially in older patients.
The FDA put out an alert about combining similar drugs in certain patients. On April 20, 2012 the agency warned doctors to be cautious about prescribing the ACE inhibitor aliskren (Amturnide, Tekturna, Tekturna HCT, Tekamio and Valturna) in combination with ARBs such as candesartan Atacand (candesartan), Avapro (irbesartan), Benicar (olmesartan), Cozaar (losartan), Diovan (valsartan), Micardis (telmisartan) or Teveten (eprosartan) in patients with diabetes or kidney problems. The combination of the ACE inhibitor and the ARB increased the risk for high potassium levels and kidney damage in people dealing with diabetes.
We get concerned whenever we hear that older people are encouraged to strive for a blood pressure reading of 120/80 with medications. When anti-hypertensive drugs cause dizziness, fatigue heart palpitations, headaches and digestive distress, the “cure” may be causing more problems than the condition being treated.
Visitors to this website have described other drug-induced side effects that have often gone under appreciated:
“I took lisinopril for a few weeks before realizing it was causing an unacceptable problem with coughing (coughing until I threw up!) My doctor put me on Diovan. It was more costly, but it worked without the coughing.” Glenda
“I took lisnopril for many years and every time I complained to my doctor who had prescribed it, about the constant nagging cough, he just prescribed cough medicine! He never told me it was the Lisnopril!
“When the coughing was so bad, I wet myself, he prescribed for incontinence!
“After 8 years, I changed doctors due to reaching 65 and going on Medicare. (My former doctor didn’t take Medicare patients.) The new doc took me off the lisnopril immediately (explained that was connection!) and put me on Losartan; the cough went away in less than a week. No more cough equaled no more losing control of bladder so he told me to toss the cough med and the incontinence med!” C.R.L.
“My doctor actually told me that the lisinipril cough was good for me! He gave me some medical mumbo-jumbo explanation of how coughing uncontrollably all day and night was not bad!!!” B.L.
“When I asked my doctor about my horrible dry cough after taking Benicar for a long time, she assured me it must be allergies as my lungs were clear. Also, I had experienced nerve pain in my feet and itching all over. I stopped taking Benicar. My BP went up to 135/75 and my cough stopped as well as the pain in my feet and itching.” G.G.
“I took Benicar and Cozaar for a year plus, and developed a horrible cough. Cardiologist said could not be medicine. Internist said it could.” E.M.F.
We have received hundreds of reports of ACE inhibitor cough linked to drugs like lisinopril. To read other stories, here is a link.
To learn more about other ways to control blood pressure, we suggest our book, Best Choices from The People’s Pharmacy. We offer a great many natural approaches to controlling hypertension with food and supplements. You can also find hints in our Guide to Blood Pressure Treatment.
All our publications can be found here.
Do not let your blood pressure medicine cause complications that affect the quality of your life. Always communicate with your physician what is going on. Share your own story with such medications below. What has worked for you without causing side effects.