By: Joe Graedon June 12, 2017 16 Comments
    Do Doctors Know How to Help Patients Stop Medica…

    Starting a new prescription is easy. If your doctor tells the pharmacist to write on the label, "take once a day with food," you know exactly what to do. Most people can manage such a simple instructi…

    By: Terry Graedon April 24, 2017 3 Comments
    Balancing the Benefits and Risks of Antidepressa…

    by Amy Beausang, PharmD What Is Depression? What if you could envision no future? If you felt like there were no answers to your problems, which are overwhelming and without end? Perhaps nothing feels…

    By: Terry Graedon April 20, 2017 1 Comments
    Should Women Worry About Antidepressants during …

    When women are pregnant, they frequently worry that something they swallow will harm the developing baby. Previous studies have suggested that mothers who take antidepressants during pregnancy might h…

    By: Joe Graedon March 30, 2017 8 Comments
    Are Men Taking Prostate Drugs More Likely to Be …

    Medications to shrink an enlarged prostate may contribute to depression. Doctors have not previously recognized this possible side effect for men taking prostate drugs. What Do Prostate Drugs Do? Drug…

    By: Joe Graedon January 19, 2017 7 Comments
    Will Antidepressant Medications Increase Your Ri…

    Antidepressants are among the most popular pills in the drugstore. A research letter in JAMA Internal Medicine (Dec. 12, 2016) noted that one in six adults take psychiatric drugs. Antidepressant medic…

    By: Joe Graedon November 28, 2016 12 Comments
    Stopping Duloxetine (Cymbalta) Suddenly Flipped …

    Antidepressants like desvenlafaxine (Pristiq), duloxetine (Cymbalta), sertraline (Zoloft) and venlafaxine (Effexor) have become extremely popular. Millions take such drugs regularly. When such medicat…

    By: Joe Graedon October 24, 2016 6 Comments
    Is Your Blood Pressure Medicine Making You Sad a…

    Do you feel down in the dumps, sad or depressed? Have you ever considered the possibility that your medicine might be responsible for your blue mood? Health professionals rarely mention that many medi…

    By: Terry Graedon October 20, 2016 8 Comments
    Curcumin Eases Both Depression and Anxiety

    Curcumin is the active ingredient in the yellow spice turmeric. Numerous studies have confirmed its antioxidant and anti-inflammatory activity. Could it help against depression and anxiety? Studying…

    By: Joe Graedon October 6, 2016 13 Comments
    Birth Control Hormones Linked to Depression

    For fifty years doctors have been wondering whether hormonal contraception could affect mood. A new study from Denmark suggests that the answer is yes. The researchers reviewed all the records for one…

    By: Joe Graedon October 6, 2016 8 Comments
    Can Psychological Depression Be Triggered By Inf…

    Health professionals have long known that depression can be brought on by challenging life events such as the loss of a loved one, marital difficulties or job loss. Genes can play a role and neuroc…

    By: Joe Graedon August 22, 2016 2 Comments
    Can Ketamine Jump Start Antidepressant Action?

    When people are severely depressed they need immediate help. Sadly, most antidepressant medications take weeks to start working. That's why this reader's question is so very interesting. Q. You've wri…

    By: Joe Graedon August 13, 2016 0 Comments
    Why Did Generic Remeron (Mirtazapine) Disappoint…

    People who are seriously depressed depend upon their medication to get through challenging times. Without a reliable medication they can fall back into a dark depression. This reader shares the frustr…

    By: Joe Graedon August 8, 2016 32 Comments
    Have You Had Problems with Generic Cymbalta (Dul…

    Brand name drugs like Cymbalta have become unaffordable for many patients. That's why most people are dispensed generic Cymbalta (duloxetine). We have received complaints that some generic formulation…

    By: Joe Graedon July 4, 2016 17 Comments
    Abilify Side effects: How Dangerous Are Antipsyc…

    Mental illness has always represented a challenge to the medical community. TV commercials to the contrary, there is no silver bullet to cure anxiety, bipolar disease, major depression or schizophreni…

    By: Joe Graedon June 23, 2016 34 Comments
    Will A Free Lunch Influence Your Doctor’s …

    Ask most physicians whether a free lunch from a drug company would affect their prescribing patterns and the chances are pretty good that they would say no. Some would be highly insulted by the very i…

    By: Terry Graedon April 4, 2016 9 Comments
    How to Fight Depression with a Simple Supplement

    Depression is common, possibly the most common mental illness. According to the CDC, this potentially crippling condition affects almost 8 percent of Americans over 12 years of age (CDC, MMWR, Jan. 6,…

    By: Terry Graedon January 28, 2016 0 Comments
    Pregnant Women Should Be Screened for Depression

    The United States Preventive Services Task Force issues recommendations for screening for a variety of diseases and conditions based on the evidence from studies. Usually these public health messages …

    By: Terry Graedon January 28, 2016 1 Comments
    Teens on Antidepressants Are More Prone to Aggre…

    Questions have been raised in the past about the balance of benefits and risks of antidepressants for youngsters. In fact, a Swedish study published in 2015 showed that people between 15 and 24 were m…

    By: Terry Graedon December 27, 2015 4 Comments
    How to Fight Back Against SAD This Winter

    As the holidays wind down and the weather changes from wet and nasty to cold and icy, many people discover that they are spending more time inside. During short days, they get relatively little sun ex…

    By: Joe Graedon December 21, 2015 14 Comments
    Billion Dollar Drugs Are Dramatically Disappoint…

    How effective is your medicine? This seemingly simple question is surprisingly complex. In many cases a pill's benefits are barely detectable. Before a drug can be approved by the Food and Drug Admini…

    By: Joe Graedon October 29, 2015 38 Comments
    Generic Sertraline (Zoloft) Problems Lead To Anx…

    The FDA insists that all generic drugs sold in the U.S. are "identical" to their brand name counterparts. Visitors to this website disagree. The latest controversy surrounds generic sertraline (Zoloft…

    By: Joe Graedon September 28, 2015 16 Comments
    Antidepressants Linked to Violence: Rape, Robber…

    Q. I am 30 years old and have been taking fluoxetine. I was prescribed this last year because I attempted to take my own life. I have noticed that my behavior, though no longer suicidal, is increasing…

    By: Joe Graedon September 17, 2015 6 Comments
    Is Paxil (Paroxetine) Unsafe for Teens?

    New research suggests that antidepressant medications may pose a serious problem for adolescents. A study from Sweden reveals a relationship between such drugs and violent crimes. More troublesome, a …

    By: Joe Graedon August 19, 2015 2 Comments
    High Glycemic Index Diets Trigger Depression

    What we eat has important effects on our physiology. Should you follow a low-carb or a low-fat diet? The controversy is ongoing. While many nutrition experts maintain firmly that all calories are equa…

    By: Joe Graedon July 16, 2015 3 Comments
    Real World Results Differ from Drug Studies

    People who are recruited to participate in studies of antidepressant medications may not represent typical depressed patients. According to a new study, subjects in clinical trials of antidepressants …

    By: Joe Graedon May 18, 2015 15 Comments
    Doctors Still Doubt Antidepressants Can Trigger …

    Shortly after Prozac was approved for treating depression in 1987 we received a heartbreaking letter from a physician. He was writing as a bereaved father: "My daughter committed suicide in 1988 one m…

    By: Joe Graedon April 23, 2015 6 Comments
    Mindfulness-Based Therapy Can Help Against Depre…

    People with recurrent depression may benefit from mindfulness-based cognitive therapy, according to a new study. The study took place in England and included 424 people with recurrent major depression…

    By: Joe Graedon April 2, 2015 3 Comments
    Roseroot May Offer Relief for Depression

    Roseroot, also known as Rhodiola rosea, has shown promise in a small study (57 subjects) of depressed individuals. Effectiveness They were randomly assigned to take either the herb, the antidepressant…

    By: Joe Graedon December 11, 2014 1 Comments
    Laughing Gas May Lead to New Depression Treatmen…

    Research on the anesthetic ketamine has shown that it can sometimes produce a quick but not long-lasting remission from otherwise intractable depression. Scientists at Washington University in St. Lou…

    By: Terry Graedon July 21, 2014 2 Comments
    Finding Affordable Treatment for Depression Is a…

    Q. I cannot tolerate oral antidepressant medications because of unacceptable side effects. My doctor has prescribed EMSAM, a skin patch, but it is very expensive. Does this medicine work for depressio…

    By: Joe Graedon July 17, 2014 21 Comments
    Do Doctors, Nurses & Pharmacists Need Educa…

    Modern medicine has shunned its past. There was a time when medical students, nursing students and pharmacy students were taught about herbal medicines. That's because many of the drugs they prescribe…

    By: Terry Graedon July 14, 2014 13 Comments
    Stopping Cymbalta Suddenly Triggered Emotional R…

    Q. Due to a change in my insurance, I wasn't able to refill my prescription for the depression drug Cymbalta. Saturday was my last dose and by Monday I felt like I was losing my mind. Today was the wo…

    By: Joe Graedon April 3, 2014 15 Comments
    Club Drug (Ketamine) Produces Exciting Benefits …

    Doctors are wrestling with the ethical and legal challenges of prescribing ketamine for severely depressed or suicidal patients. The drug may help some people, but doctors worry about the possibility …

    By: Terry Graedon November 21, 2013 6 Comments
    Cognitive Behavioral Therapy for Insomnia Helps …

    Insomnia and depression often go hand in hand. Researchers have wondered whether it's a chicken or egg phenomenon. In other words, does depression trigger insomnia or do sleeping problems contribute t…

    By: Terry Graedon October 31, 2013 1 Comments
    Regular Exercise Helps Prevent the Onset of Psyc…

    There is ample evidence that exercise can be beneficial in treating mild to moderate depression. A new analysis of 30 long-term prospective trials of physical activity and depression found that in the…

    By: Terry Graedon September 19, 2013 1 Comments
    Exercise Is Effective Treatment for Psychologica…

     Exercise seems to help people overcome mild to moderate depression. A new study analyzed data from 35 trials that randomly assigned people to either exercise or control groups. Exercise was roughly …

    By: Terry Graedon August 19, 2013 23 Comments
    Easing Depression without Drugs

    Q. After taking various antidepressants for many years, I tried to stop. The first time I decreased the levels of medication over five weeks. I experienced many incapacitating withdrawal symptoms and …

    By: Terry Graedon June 10, 2013 8 Comments
    Old Drug Has New Tricks Against Depression

    When someone is severely depressed, immediate action is essential. That's because without help or hope, a suicidal person may do himself irreversible harm. The trouble is that most antidepressant trea…

    By: Terry Graedon June 6, 2013 6 Comments
    Quick Relief from Depression

    An old drug is stimulating a great deal of excitement within the psychiatric community. Ketamine was introduced in the 1970s as an anesthetic. Although it was effective, it had certain drawbacks. The …

    By: Joe Graedon November 22, 2012 1 Comments
    Will Fish Oil Fight Postpartum Depression?

    Psychiatrists in Canada have found that low levels of omega 3 fats are linked to a higher risk for postpartum depression. Levels of this critical nutrient drop in the mother during pregnancy while fet…