By: Joe Graedon April 29, 2019 8 Comments
    Will Ketamine Really Battle Life-Long Depression…

    People with depression have a really tough time. Not only does the condition suck all of the joy out of life, the medications used to treat it have some potentially serious side effects. Moreover, ant…

    By: Joe Graedon April 22, 2019 20 Comments
    Why Is This Pharmacist Complaining About Levothy…

    Let’s get one thing straight. We are mad as hell about drug shortages. There is no question that important medicines have been in short supply for years and the FDA has done very little to help corr…

    By: Joe Graedon April 22, 2019 6 Comments
    Falling Asleep with Zolpidem | Waking up with He…

    What do you do when you are caught on the horns of a dilemma? We describe such situations a couple of ways: “Between the devil and the deep blue sea” is one. A similar saying goes: “between a ro…

    By: Terry Graedon April 22, 2019 9 Comments
    Do Drug-Resistant Germs Hide Out in Hospitals?

    In the 19th century, nobody wanted to go to the hospital. Before antibiotics were discovered, people considered these institutions as the very last resort. The wards were unfriendly and frequently con…

    By: Joe Graedon April 18, 2019 8 Comments
    Medical Marijuana Users May Require More Anesthe…

    Millions of people are now using cannabis regularly. Some smoke marijuana. Others eat marijuana gummies, brownies, chocolate bars, truffles and chocolate chip cookies. Then there is medical marijuana.…

    By: Terry Graedon April 15, 2019 7 Comments
    What Is the Story on Grapefruit Juice and Meds?

    What do you know about the story on grapefruit juice and drug interactions? Some people have heard that it is risky to combine juice but not fruit with certain medications; others insist that the inte…

    By: Terry Graedon April 15, 2019 7 Comments
    Go Easy on Licorice to Avoid Leg Cramps

    Your mother probably told you not to eat too much candy because it could ruin your teeth. Maybe your grandmother warned that gobbling candy would make you gain weight. But did anyone tell you to go ea…

    By: Joe Graedon April 15, 2019 11 Comments
    Polypharmacy and Premature Deaths Especially in …

    Have you been to a doctor’s office or a clinic lately? Chances are very good that a med tech weighed you, measured your blood pressure and took your temperature. This information was entered into a …

    By: Joe Graedon April 15, 2019 22 Comments
    Gabapentin and Fuzzy Thinking: A Recognized Side…

    We have been writing a lot about GABA drugs like gabapentin (Neurontin) and pregabalin (Lyrica). That because a report from ISMP (Institute for Safe Medication Practices) has a QuarterWatch article: …

    By: Joe Graedon April 11, 2019 9 Comments
    FDA Approves Evenity to Build Bone Against Osteo…

    The FDA has just approved a new drug for osteoporosis that works differently than existing medications. Romosozumab will be sold under the brand name Evenity. This injectable monoclonal antibody actua…

    By: Terry Graedon April 11, 2019 5 Comments
    Show 1160: How Good Is the Evidence for Cutting …

    For decades, public health experts have been admonishing Americans to cut the salt in our diets. In fact, the American Heart Association recommends that we limit ourselves to 2,300 mg of sodium daily.…

    By: Terry Graedon April 11, 2019 14 Comments
    Scary Drug-Resistant Fungal Infection Is Spreadi…

    A life-threatening drug-resistant fungal infection is spreading around the country. The Centers for Disease Control and Prevention (CDC) are reporting outbreaks of Candida auris in 12 states. New York…

    By: Terry Graedon April 8, 2019 7 Comments
    Should You Take Your Aspirin with Honey?

    When we were kids, we were amused by a silly poem that went like this: "I eat my peas with honey. "I've done it all my life. "It makes the peas taste funny, "but it keeps them on my knife." We were eq…

    By: Terry Graedon April 8, 2019 11 Comments
    Will It Hurt to Switch Generic Levothyroxine?

    Levothyroxine, or T4 thyroid hormone, is a very old medication. Scientists first extracted this compound from pig thyroid glands more than 100 years ago, but no drug maker marketed the synthetic form …

    By: Joe Graedon April 8, 2019 10 Comments
    Doctors Deny That PPIs Can Cause Kidney Damage

    It can take years or even decades to discover serious drug side effects. Think of it as a long-running drug experiment. Proton pump inhibitors like esomeprazole (Nexium), lansoprazole (Prevacid) and o…

    By: Terry Graedon April 8, 2019 16 Comments
    Will Probiotics Help You Recover from Antibiotic…

    Antibiotics are crucial tools for overcoming serious infections. However, they can often kill beneficial bacteria that live in the digestive tract and elsewhere along with the harmful invaders. As lon…

    By: Joe Graedon April 4, 2019 23 Comments
    New Concerns About Gabapentin and Pregabalin (Ly…

    A recent review of the FDA’s Adverse Event Reporting System (FAERS) reveals some disconcerting data about commonly prescribed drugs for nerve pain (ISMP QuarterWatch Reports (March 27, 2019). This i…

    By: Joe Graedon April 1, 2019 29 Comments
    Will Statins Protect the Brain and Lower Blood S…

    We have written on several occasions that statins are linked to diabetes. The most recent article was this one: “Statins Cause Diabetes: The Link Just Got Stronger!” Before that we wrote: "Statins…

    By: Joe Graedon April 1, 2019 20 Comments
    Benzodiazepine Dependence | A Hard Habit to Kick

    When most people hear the words “drug abuse” they think of opioids like oxycodone, hydrocodone or heroin. Other contenders include stimulants like cocaine and methamphetamine (“meth”), alcohol…

    By: Joe Graedon April 1, 2019 8 Comments
    Generic Escitalopram (Lexapro) Bombs Out Against…

    Escitalopram (Lexapro) is an SSRI (selective serotonin reuptake inhibitor). That means it is a lot like fluoxetine (Prozac). We have lost confidence in the FDA’s ability monitor generic drug quality…

    By: Joe Graedon March 28, 2019 6 Comments
    Why Should You Care about the Xarelto and OxyCon…

    We don’t usually report on litigation. Although legal cases often involve a LOT of scientific evidence, the outcomes are not always trustworthy. Just because a jury finds a product deficient or dang…

    By: Joe Graedon March 25, 2019 20 Comments
    Aviation Disasters Highlight Fundamental Flaws a…

    When an airplane crashes it captures the world’s attention. When two planes crash it instantly becomes a crisis. Such was the case with the Boeing 737 Max 8 airplane. On October 29, 2018, 189 people…

    By: Terry Graedon March 25, 2019 1 Comments
    Does Your Microbiota Change When You Take Nexium…

    The "royal we" may be more accurate than we imagine, and not only for individuals of noble descent. All of us might practice thinking of ourselves a a collective. That is because each of us contains m…

    By: Joe Graedon March 25, 2019 17 Comments
    Another ARB Recall Translates into Bad BP Contro…

    Yup, you guessed it. The FDA has issued another ARB recall. This time it is for losartan…again. On March 15, 2019 and again on March 19, 2019 the FDA announced that Legacy Pharmaceutical Packaging, …

    By: Joe Graedon March 21, 2019 22 Comments
    Statins Cause Diabetes: The Link Just Got Strong…

    There is no nice way to say this. Cholesterol-lowering drugs like statins cause diabetes. This is not new news, but it is unwelcome. When lovastatin (Mevacor) was approved by the FDA more than 30 year…

    By: Joe Graedon March 18, 2019 11 Comments
    How To Stop Venlafaxine: Very, VERY Slowly!

    It has taken the medical profession a very long time to acknowledge that many of the most popular drugs in the pharmacy can cause a kind of dependence. By that we mean such drugs can precipitate serio…

    By: Joe Graedon March 18, 2019 12 Comments
    Delayed Cough with Lisinopril Can Lead to Misdia…

    Humans are programmed to quickly associate symptoms with exposure to some toxin. This was an incredibly adaptive learning process when our ancestors were hunters and gatherers. If a member of the trib…

    By: Joe Graedon March 18, 2019 13 Comments
    Doctor Disses Oseltamivir (Tamiflu) Against Flu

    Watch out, there’s a second wave of nasty influenza starting to circulate. Even though it seems as if spring is right around the corner, a lot of people are suffering from this badass H3N2 strain of…

    By: Joe Graedon March 18, 2019 47 Comments
    Best Home Remedies for Restless Legs Syndrome

    Restless legs syndrome (RLS) affects 5% to 15% of adults (Journal of Clinical Sleep Medicine, Dec. 15, 2016). That means as many as 30 million Americans suffer from RLS. Roughly 6 million people are s…

    By: Joe Graedon March 14, 2019 43 Comments
    Physicians Finally Fed Up With the FDA and ARB R…

    Week after week, month after month, we have been learning about ARB recalls. These angiotensin receptor blockers have been taken by at least two million Americans to control blood pressure or treat he…

    By: Joe Graedon March 11, 2019 10 Comments
    PPIs and Kidney Damage | Nephrologist Spanks GI …

    Many specialists live in silos. By that we mean they hang out with other experts like themselves. They reinforce each other’s understanding of the world. These specialists may not hang out with auth…

    By: Joe Graedon March 11, 2019 14 Comments
    Taking Lisinopril | Avoid POTASSIUM but ZINC Cou…

    Lisinopril is about the most popular drug in the pharmacy. This ACE (angiotensin converting enzyme) inhibitor is swallowed by over 20 million hypertensive Americans every day. Over 110,000,000 bo…

    By: Joe Graedon March 11, 2019 19 Comments
    There’s an Easy Trick to Talk to the Pharm…

    There was a time when most of the pharmacies in America were owned and operated by a pharmacist. They were friendly gathering places. The pharmacist knew your name and probably everyone in your family…

    By: Terry Graedon March 11, 2019 15 Comments
    Can You Overcome Allergies with Xlear?

    Every year as allergy season arrives, people who suffer from allergies look for solutions. Antihistamines such as cetirizine (Zyrtec), fexofenadine (Allegra), levocetirizine (Xyzal) or loratadine (Cla…

    By: Joe Graedon March 7, 2019 8 Comments
    A New Carcinogen Found in BP Meds | More ARB Rec…

    How many times have we said, Not Again? We are, sadly, referring to ARB recalls. ARBs are short for angiotensin receptor blockers. They treat high blood pressure. Basically, it boils down to another w…

    By: Terry Graedon March 7, 2019 13 Comments
    No Link Between Vaccine and Autism in Denmark

    There are half a dozen measles outbreaks currently underway in the US, as well as several serious international outbreaks. Consequently, the news on measles vaccine from Denmark is important. Scientis…

    By: Joe Graedon March 4, 2019 14 Comments
    Clindamycin and C. Diff Infection: A Devil’s R…

    The FDA has a black box warning in the prescribing information for clindamycin (Cleocin). That represents the highest alert for physicians and patients about this antibiotic. It says in part: “Becau…

    By: Joe Graedon March 4, 2019 17 Comments
    FDA Boss Infuriates Patients with Drug Safety Tw…

    Dr. Scott Gottlieb is the Commissioner of the Food and Drug Administration. That means he is the top cop when it comes to all our medications. Dr. Gottlieb stirred up a lot of excitement on Valentine…

    By: Terry Graedon February 28, 2019 0 Comments
    How Can Viruses Fight Antibiotic-Resistant Bacte…

    The CDC estimates that at least 23,000 Americans die each year from antibiotic-resistant infections. Researchers expect this problem will only get worse in coming years. Finding new antibiotics has be…

    By: Terry Graedon February 25, 2019 1 Comments
    Are You Giving Your Child the Right Dose?

    What do you do when your young child gets a fever, a cough or a sore throat? If you’re like most parents, you look around the medicine chest for something to ease the symptoms. But what will you fin…