By: Joe Graedon March 28, 2013 33 Comments
    Carvedilol Side Effects from Generic Coreg

    One of the most popular beta blockers being prescribed these days is carvedilol (Coreg). Even though this class of medication is no longer perceived by most cardiology experts as appropriate first-lin…

    By: Terry Graedon March 21, 2013 1 Comments
    Generic Lipitor Lures Shoppers

    Some stores like to offer loss leaders to attract shoppers. This usually involves products like cereal, soft drinks, or facial tissue being sold at, or below, cost. Now supermarket chains are using th…

    By: Terry Graedon January 21, 2013 58 Comments
    Scary Generic Coreg (Carvedilol) Side Effects

    Q. My wife has been taking Coreg for 10 years and doing well. Last week she was advised that a generic version of the drug (carvedilol) was available. At the advice of the pharmacist (who insisted tha…

    By: Terry Graedon January 10, 2013 28 Comments
    Generic Drug Equivalency Coming Unraveled

    For decades, we were told by the FDA, physicians, pharmacists and consumer organizations that generic drugs were "identical" to their brand name equivalents. We believed them. In fact, we led the char…

    By: Terry Graedon December 3, 2012 10 Comments
    Did Glass in Atorvastatin Pills Damage Stomach?

    By now you should have heard that the huge Indian generic drug company, Ranbaxy, finally agreed to halt production of its generic Lipitor (atorvastatin) because somehow glass particles got into the pr…

    By: Terry Graedon November 27, 2012 6 Comments
    Where Did Contaminated Atorvastatin Come From?

    By now you no doubt know that a generic formulation of Lipitor (atorvastatin) made by the Indian company Ranbaxy was contaminated with small glass particles. The company announced its recall last week…

    By: Terry Graedon November 23, 2012 30 Comments
    Breaking News: Atorvastatin (Generic Lipitor) Re…

    Lipitor has been the most successful drug in the history of the pharmaceutical industry. Nothing else even gets close. Sales of Lipitor exceeded more than $130 billion. In its heyday millions of peopl…

    By: Joe Graedon October 22, 2012 5 Comments
    Patient Relieved at Drug’s Removal

    Q. I am so relieved that the FDA finally got the antidepressant Budeprion XL 300 off the market. Years ago my insurance company switched me from Wellbutrin XL 300 to Budeprion XL 300. Within a short t…

    By: Joe Graedon October 15, 2012 17 Comments
    Popular Generic Antidepressant Recalled

    On October 3, 2012 the FDA announced that the generic antidepressant Budeprion XL 300 (bupropion) was not identical to the brand name drug Wellbutrin XL 300 and would be removed from pharmacy shelves.…

    By: Terry Graedon September 3, 2012 105 Comments
    Patients Vindicated! Generic Wellbutrin Withdraw…

    We are reposting our People's Pharmacy Alert from October 3, 2012 because of The New York Times article about "An Increase in Scrutiny for Generics." On October 3, 2012, the Food and Drug Administrati…

    By: Terry Graedon September 3, 2012 19 Comments
    Whom Do You Trust Re: Generic Drugs?

    The Food and Drug Administration has a culture of secrecy and a seeming lack of concern about reports of generic drug failures from patients, physicians and pharmacists. The response from the FDA, if …

    By: Terry Graedon August 27, 2012 5 Comments
    Trouble with Generic Bupropion

    Q. Three times I have been forced by my insurance company to switch from Wellbutrin XL to generic bupropion. Each time depression reared its ugly, gloomy head and darkness descended again. Wellbutrin …

    By: Terry Graedon April 9, 2012 8 Comments
    Generic Drug Is Matter of Life and Death

    Q. My husband is suffering seizures after being forced to switch to generic levetiracetam (Keppra). I can buy the brand for $735.00 per month, but at 62 years of age we can't afford to spend this much…

    By: Terry Graedon February 27, 2012 10 Comments
    Generic Cholesterol Drug Didn’t Work

    Q. I am a cardiologist with a patient who had elevated cholesterol in 2010. Her total cholesterol was 245 and her LDL was 156. This was too high, so I put her on Pravachol. It brought her cholesterol …

    By: Joe Graedon February 19, 2012 27 Comments
    Are People Who Complain About Generic Drugs Nut …

    Q. Never, never, never trust random folks on the internet for med advice. Generic drugs have to be the exact same thing as the brand name by law. The bioavailability as well as the delivery system als…

    By: Terry Graedon August 17, 2011 7 Comments
    Generic Drug Inspections Proposed

    Over the last decade or so there have been growing concerns about the quality of generic drugs. That is because 40 percent of the finished products and 80 percent of the raw ingredients are manufactur…

    By: Terry Graedon June 13, 2011 45 Comments
    Generic Xanax Generates Anxiety

    Q. The generic form of Xanax, alprazolam, does not work for me. It is at best 50 percent effective. A few years ago I was given alprazolam in place of Xanax. My panic attacks came back with a vengeanc…

    By: Terry Graedon May 15, 2011 12 Comments
    Kidney Transplant Failure

    Q. My husband was hospitalized for acute kidney transplant rejection. The doctor was very concerned when told that he had switched a few months earlier to generic tacrolimus. He had been on Prograf fo…

    By: Joe Graedon April 11, 2011 160 Comments
    Why Pharmacists Are Wrong About Generic Drugs

    Most (but not all) pharmacists routinely tell patients that generic drugs are identical to brand name medications. That is hardly surprising. This is what pharmacy students are told during their educa…

    By: Joe Graedon March 17, 2011 63 Comments
    Generic Prozac Was A Downer

    Q. My husband has been taking Prozac successfully for years. He was recently switched to generic fluoxetine. In the last several months he has become much the same person he was before Prozac--angry, …

    By: Joe Graedon January 24, 2011 51 Comments
    Pharmacist Spills the Beans on Generic Drug Orig…

    I am a pharmacist with 40 years of practice. I am very disturbed about the generic drugs that are coming into this country from who knows where. Unfortunately, we have little choice in choosing a gene…

    By: Terry Graedon November 7, 2010 19 Comments
    Should Generic Drugs Be Safer?

    For decades the FDA has reassured physicians, pharmacists and patients that generic drugs are identical to their brand name counterparts. Insurance companies love this guarantee. They often require pa…

    By: Terry Graedon August 5, 2010 10 Comments
    Trouble with Generic Seizure Medicine

    Q. I'm 17 years old and I have epilepsy. I started taking Keppra two years ago. It got my seizures under control and I went into remission. I recently moved to a new state and my new doctor switched m…

    By: Terry Graedon July 21, 2010 25 Comments
    Trouble Switching between Generic Levothyroxine …

    Q. I have taken levothyroxine for several years but my insurance keeps changing the brand (from Synthroid to Levothroid to several generics). I have had progressively deteriorating hypothyroid symptom…

    By: Terry Graedon April 11, 2010 3 Comments
    Are Your Pills Legit?

    When you think about big heists, what comes to mind? Diamonds? Cash stolen from an armored car? Perhaps a priceless painting from a museum? Prescription drugs turn out to be a growing target for thiev…

    By: Terry Graedon February 16, 2010 2 Comments
    Diabetes Drug Smells Awful

    People with type-2 diabetes are often prescribed a drug called metformin. It is quite effective in helping to control blood glucose. But there is a problem with this medication. Many patients stop tak…

    By: Joe Graedon December 17, 2009 232 Comments
    Generic Drug Controversy Won’t Quit!

    The FDA maintains that all generic drugs are "identical" to their brand name counterparts. Of course, the word identical does not mean the same thing to everyone. Most of us assume that identical mean…

    By: Terry Graedon December 7, 2009 61 Comments
    Study to Compare Brand Name and Generic Antidepr…

    Q. Is there anything new on the generic version of Wellbutrin XL? My wife had done well on the brand name and then the Watson generic bupropion for several years. She was abruptly switched to Teva Bud…

    By: Terry Graedon August 6, 2009 14 Comments
    Quality of Generic Drugs Questioned

    Questions about generic drug quality persist despite FDA reassurances. More than a year ago the Actavis Group had to voluntarily recall 800 million digoxin tablets because of doubts about the dose. A …

    By: Terry Graedon July 2, 2009 2 Comments
    FDA Seizes Generic Drugs

    The Food and Drug Administration recently seized substantial numbers of generic drugs that did not live up to good manufacturing practices. This is not the first time the feds have taken action on gen…

    By: Joe Graedon May 25, 2009 46 Comments
    Generic Drug Recall Linked to Deaths

    In times of economic hardship, low-cost generic drugs can be lifelines. They make it possible for people to continue critical medications. Without them, people could die. But if generic drugs don't me…

    By: Joe Graedon March 13, 2009 32 Comments
    How Good Is Generic Anti-Epilepsy Drug?

    Q. I need more information about the generic for the epilepsy drug Keppra. I understand that the generic is fairly new.Is it safe to take, and does it have the same active ingredient as Keppra?A. Gene…

    By: Joe Graedon February 16, 2009 41 Comments
    Are Generic Drugs Really Identical?

    In answering the question What are Generic Drugs? on its Web site, the Food and Drug Administration states unequivocally: “A generic drug is identical, or bioequivalent to a brand name drug in d…

    By: Joe Graedon December 15, 2008 5 Comments
    Is It Safe to Save Money on Generic Drugs?

    Everyone loves a bargain. Imagine buying a new Mercedes-Benz worth $60,000 for the price of a Hyundai, say around $20,000. As long as the vehicle had Mercedes parts and performed like a Mercedes, you …

    By: Joe Graedon October 6, 2008 14 Comments
    Where Do Generic Drugs Come From?

    Here we go again. First it was pet food from China contaminated with melamine. Then it was Chinese-made toothpaste containing diethylene glycol, an ingredient found in some antifreeze.Another scandal …

    By: Joe Graedon September 9, 2008 2 Comments
    Generic Drugs Come Under Scrutiny

    How good are generic drugs? The FDA tells everyone--patients, physicians, pharmacists, hospitals and insurance companies--that generic drugs are identical to their brand name counterparts. But the FDA…

    By: Joe Graedon August 3, 2008 9 Comments
    Indian Drug Firm In Trouble with FDA and Justice

    A story that was virtually ignored by the mainstream press and disappeared almost without a trace has to do with serious allegations against Ranbaxy Laboratories, an Indian drug company. Ranbaxy is no…

    By: Joe Graedon May 5, 2008 8 Comments
    Questions Remain Despite FDA Report

    For years, the FDA has reassured everyone who prescribes, dispenses or pays for prescription medicine that generic drugs are absolutely equivalent to brand-name drugs. Because brand name medications a…

    By: Joe Graedon April 7, 2008 2 Comments
    FDA On The Hot Seat Over Heparin Horror

    Americans have been repeatedly told that we have the safest medicines in the world. That's because the FDA has the reputation for policing our drug supply conscientiously. The recent scandal over the …

    By: Joe Graedon April 2, 2008 103 Comments
    Disappointed with Generic Sleeping Pill

    Q. I have suffered with insomnia for years. My doctor prescribed Ambien, which gives me eight hours of restful sleep. Then the pharmacist switched me to generic zolpidem for under $15. He said it was …