By: Joe Graedon November 30, 2015 15 Comments
    Price Differential between Brand-Name and Generi…

    There is no question that generic drugs can offer big savings. Sometimes it is worthwhile to see just how great the price difference might be. Q. My sister takes brand name Ativan, as her doctor does…

    By: Joe Graedon November 26, 2015 15 Comments
    Doctors Endorse Generic Drugs to Save Money-But …

    A key organization says that doctors should write more prescriptions for generic drugs to hold down the high cost of medicines. That sounds reasonable. Why might this recommendation be problematic? We…

    By: Joe Graedon October 29, 2015 97 Comments
    Generic Sertraline (Zoloft) Problems Lead To Anx…

    The FDA insists that all generic drugs sold in the U.S. are "identical" to their brand name counterparts. Visitors to this website disagree. The latest controversy surrounds generic sertraline (Zoloft…

    By: Joe Graedon October 14, 2015 14 Comments
    Are US Drug Prices Exorbitant?

    Americans are paying more for medicines than people anywhere else in the world. That's the conclusion from an analysis commissioned by the news agency Reuters. Investigators at the University of Liver…

    By: Joe Graedon October 4, 2015 17 Comments
    Is Drug Company Greed Out of Control?

    Are drug companies killing the goose that lays their golden eggs? In this ancient fable, a farmer and his wife discover that their goose is laying golden eggs. They become so greedy that they slaughte…

    By: Joe Graedon September 27, 2015 17 Comments
    Save Money Safely With Authorized Generic Drugs

    People have become suspicious of the quality of generic drugs. Is there a way to benefit from the lower cost of these copycat medicines without sacrificing effectiveness? What are Authorized Generic D…

    By: Joe Graedon September 14, 2015 15 Comments
    Pain with Switch from Celebrex to Celecoxib

    People with arthritis frequently rely on medication to fight the pain and inflammation of their condition. When a drug works well, they stick with it. It can be a disappointment to discover that a dif…

    By: Joe Graedon August 24, 2015 44 Comments
    Generic Drugs Banned in Europe But Not in the US

    Over a year ago we received a message from a pharmaceutical research scientist. He worked for a large clinical research company in India that tested generic drugs to see whether they reached blood lev…

    By: Joe Graedon July 16, 2015 51 Comments
    More Drug Recalls From India – Do You Trus…

    The overwhelming majority of generic drugs are now made abroad. India supplies a large proportion of those formulations. In recent days two large Indian drug companies have received bad news from the …

    By: Joe Graedon June 1, 2015 4 Comments
    Help with Pricey Prescription Drug Bills

    Pricey prescription drug bills are a serious problem for anyone paying out of pocket or whose insurance has a hefty copay. (That may be most of us these days.) Having the doctor write the correct pres…

    By: Joe Graedon May 25, 2015 26 Comments
    Can You Put Lipstick on Big Pharma and Its Piggy…

    Big Pharma has a problem. According to the Wall Street Journal, "Drug Makers are Having Trouble Improving Their Reputations." A new survey shows that drug companies are not perceived as outstanding in…

    By: Joe Graedon May 18, 2015 15 Comments
    Does FDA Care Whether Generic Drugs Work?

    There has been a lively debate about whether generic drugs are truly equivalent to their brand-name equivalents. That has been stirred up even further by questions about the effectiveness of certain g…

    By: Joe Graedon April 23, 2015 5 Comments
    Joe Graedon Discusses Generic Drugs on WTVD

    Joe Graedon talked about the pros and cons of generic drugs on ABC11 (WTVD Durham NC) on April 22, 2015. Here's a link. Saving money is a big advantage, but only if the medication works properly. How …

    By: Joe Graedon March 23, 2015 24 Comments
    Soaring Generic Drug Prices Squeeze Patients

    Q. Has anyone done some investigative journalism to expose why several generic medication prices have skyrocketed? My clobetasol ointment has gone up 300 percent over the last year. My understanding i…

    By: Joe Graedon March 2, 2015 14 Comments
    Is the FDA Protecting Drug Companies Instead of …

    For decades we were staunch defenders of the FDA. We thought the agency did an amazing job protecting consumers from bogus products. We applauded the organization for making sure Americans' medication…

    By: Joe Graedon March 2, 2015 332 Comments
    Does Generic Celecoxib Measure Up to Celebrex?

    Q. My doctor prescribed Celebrex several years ago to help ease the arthritis pain in my knee. Three days ago my pharmacy substituted with generic celecoxib. I was pleased with the savings, but my pai…

    By: Joe Graedon January 15, 2015 4 Comments
    FDA Is Concerned about Drug Quality

    The Food and Drug Administration has just announced a restructuring. The agency will be adding a new department, the Office of Pharmaceutical Quality, to rectify some serious manufacturing problems th…

    By: Joe Graedon December 29, 2014 17 Comments
    Generic Drug Failure Can Be Life Threatening

    Q. My 7-year-old child had not had a seizure in four years. Her epilepsy has been controlled with Keppra and the ketogenic diet. Recently, she was switched to levetiracetam, the generic form of Keppra…

    By: Joe Graedon December 7, 2014 2 Comments
    Questions About Generic Forms of Concerta

    Q. I was delighted to read about FDA concerns regarding generic Concerta. My prescription insurance is going to an essentially generic-only pricing system that will push the price of brand-name Concer…

    By: Joe Graedon December 3, 2014 34 Comments
    Expose Reveals Why We No Longer Trust All Generi…

    For more than 25 years we were among the most enthusiastic boosters of generic drugs in America. That began to change in the late 1990s because we were receiving so many complaints from patients. Inve…

    By: Joe Graedon November 24, 2014 3 Comments
    Generic Drug Prices Are Skyrocketing

    Generic drugs are supposed to be inexpensive alternatives to pricey brand name medications. But in recent months there has been a surge in the price of some generic drugs, making them absurdly expensi…

    By: Joe Graedon November 17, 2014 41 Comments
    FDA Drops a Bombshell on Slow-Release Generic Dr…

    The Food and Drug Administration's announcement last week that two generic Concerta formulations might not work as well as the brand name medication has rekindled questions about the FDA's generic dru…

    By: Joe Graedon September 24, 2014 11 Comments
    People’s Pharmacy Expertise Featured on Ni…

    We have been  campaigning for transparency in generic drug approval, manufacturing and distribution for over a decade. That's because we have heard from so many visitors to this website about difficu…

    By: Terry Graedon August 4, 2014 5 Comments
    Stopping Cymbalta Triggered More Frequent Attack…

    Q. I have narcolepsy with cataplexy. Cataplexy is sudden loss of muscle tone brought on by strong emotion, such as fear, anger or excitement. In my case, it is triggered by laughter. I can go a long t…

    By: Terry Graedon June 26, 2014 5 Comments
    Generic Metoprolol Pills Are Recalled by Manufac…

    Another Indian generic drug company is recalling an important heart medicine called metoprolol. Dr. Reddy's Laboratories determined that their 25 mg metoprolol tablets did not dissolve as expected. Ov…

    By: Joe Graedon June 25, 2014 9 Comments
    We’re Not the Only Ones! Cleveland Clinic …

    Last week the FDA announced another metoprolol succinate recall. This time it was from the Indian generic drug company Dr. Reddy's Laboratories. The 25 mg metoprolol pills failed a dissolution test. I…

    By: Joe Graedon June 22, 2014 75 Comments
    Another Metoprolol Recall Reveals the Dark Side …

    Here we go again: another generic metoprolol recall from an Indian drug company. The FDA announced problems with Dr. Reddy's metoprolol succinate 25 mg extended release tablets and the company is in t…

    By: Joe Graedon May 15, 2014 71 Comments
    Metoprolol Mess (Toprol XL) Reveals Serious Flaw…

    The FDA has just announced that a maker of generic Toprol XL will have to recall 109,744 bottles of metoprolol succinate. That could represent a substantial number of pills. Wockhardt is a large India…

    By: Terry Graedon April 6, 2014 73 Comments
    Not All Generic Forms of Zolpidem Induce Sleep f…

    Q. Insurers require us to use generic drugs. My wife and I both take Ambien when we travel, which is quite often. If we were buying brand name Ambien, it would cost us over $350 out of pocket for 30 p…

    By: Terry Graedon March 10, 2014 11 Comments
    FDA Launches a New Program to Test Generic Drugs…

    The Food and Drug Administration is about to launch the first generic drug testing program in America's history. Thank goodness. We have relied upon the honor system for far too long. Physicians, phar…

    By: Terry Graedon March 6, 2014 3 Comments
    Accuracy of Prescribing Information for Generic …

    The manufacturers of generic drugs are fighting an FDA proposal that would require them to update the prescribing information when new dangers come to light. This would level the playing field between…

    By: Joe Graedon February 22, 2014 96 Comments
    FDA Agrees to Start Testing Generic Drugs –…

    Without admitting that there is a problem with generic drugs, the  U.S. Food and Drug Administration has just announced that it is initiating a $20 million testing program. The FDA's new Office of Ph…

    By: Joe Graedon February 15, 2014 102 Comments
    Why We Have Lost Confidence in Generic Drugs: Ne…

    Gardiner Harris has written a powerful front-page story for the New York Times titled "Medicines Made in India Set Off Safety Worries" (Feb. 15, 2014). If anything, the headline downplays the seriousn…

    By: Terry Graedon February 13, 2014 3 Comments
    FDA Head’s Travel to Address Quality Contr…

    The FDA has long maintained that generic drugs are every bit as good as their brand name counterparts. But in recent years the agency has had  to crack down on foreign generic drug manufacturers beca…

    By: Joe Graedon January 28, 2014 74 Comments
    Indian Generic Drug Firm Ranbaxy Is in Big Troub…

    The FDA has just banned the importation of pharmaceutical ingredients from the largest drug company in India, but it is not the first time. Four of Ranbaxy's five manufacturing facilities once made dr…

    By: Terry Graedon January 15, 2014 14 Comments
    More Trouble for Indian Generic Manufacturer Cou…

    Over 80 percent of the prescription medications that Americans now buy from pharmacies are generic rather than brand name. The majority of the ingredients in those pills come from abroad. India and Ch…

    By: Terry Graedon January 6, 2014 14 Comments
    Be Wary of Stratospheric Increases in Generic Dr…

    Generic medications are supposed to be a bargain. According to the FDA, patients may be able to save as much as 80 percent on some products. Big box discount stores have enticed customers with a three…

    By: Terry Graedon October 28, 2013 13 Comments
    Why Don’t You Trust Generic Drugs as Much …

    Why don't patients and their doctors trust generic drugs? Despite the fact that 84 percent of all prescriptions are dispensed in their generic form, there is still a great deal of skepticism about the…

    By: Terry Graedon October 17, 2013 56 Comments
    FDA Follow-Up Finds Another Generic Bupropion Fa…

    The Food and Drug Administration has issued a long-awaited report on the quality of a generic antidepressant. Last October the FDA reported that one generic form of the drug Wellbutrin did not meet it…

    By: Joe Graedon July 4, 2013 23 Comments
    Generic Switch Triggers Diazepam Side Effects &#…

    Q. I had horrific side effects from 5mg diazepam when I was switched to a different generic diazepam. The first time I took the new pills, I woke up feeling like I was being shocked or as if I were ha…