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Will Ibuprofen Counteract Aspirin’s Cardiac Benefits?

Q. Are there problems associated with taking daily low-dose aspirin for cardiac protection along with ibuprofen for pain relief? I’ve read that taking an NSAID like ibuprofen can negate the desired effects of the aspirin.

A. It is estimated that half of older adults take aspirin regularly, in large measure to protect their hearts (Clinical Medicine & Research, online, Feb. 26, 2014). One way this ancient medicine works is by keeping the sticky part of blood (platelets) from clumping and causing clots that could trigger a heart attack or stroke.

Taking a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen or naproxen may undo this cardiovascular benefit. That’s because such drugs compete with aspirin and keep it from doing its anti-clotting job. Research suggests that taking the NSAID pain reliever at least two hours after aspirin and eight hours before the next dose might reduce the potential interaction (Thrombosis and Haemostasis, May, 2013).

There is more information on aspirin’s benefits, interactions and risks in our free Guide to Key Aspirin Information.

5/10/18 redirected to: https://www.peoplespharmacy.com/articles/how-do-you-weigh-the-benefits-and-risks-of-aspirin/

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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