The People's Perspective on Medicine

Statin Side Effects Are All In Your Head! Really?

The headlines have taken our breath away:

“Statin Side-Effects Questioned”

“Statins do NOT have major side effects, claims study”

“Statins Have Virtually No Side-Effects, Study Finds”

“Side Effects Reported in Those Taking Statins Are Not Actually Attributable to the Drugs”

“Statins have ‘fewer side effects than placebo’, suggests UK study”

These headlines all resulted from an article published in The European Journal of Preventive Cardiology (March, 2014).

The authors concluded:

“At the doses tested in these 83,880 patients, only a small minority of symptoms reported on statins are genuinely due to the statins: almost all reported symptoms occurred just as frequently when patients were administered placebo. New-onset diabetes mellitus was the only potentially or actually symptomatic side effect whose rate was significantly higher on statins than placebo; nevertheless, only 1 in 5 of these new cases were actually caused by statins.”

So, what are we to make of this? Clearly, the media has announced to the world that statin-type drugs do not cause side effects. Reporters have gone so far as to suggest that sugar pills (placebos) cause more complications than statins. In other words, if you think your atorvastatin (Lipitor), lovastatin (Mevacor), rosuvastatin (Crestor) or simvastatin (Zocor) could be responsible for your muscle pain, weakness, mental confusion, nerve discomfort or cataracts, you are wrong. Such symptoms are all in your head. The only possible drug-induced complication of statins (according to these authors) is diabetes.

Pretty much ignored by the press has been a section in this article titled: “Comparison with real-live clinical experience.” The authors admit that:

“Many real-world patients report muscle-related symptoms with statins. This contrasts with the low placebo subtracted rate in blinded trials shown in this meta-analysis. Several explanations are possible. First, commercial sponsors of clinical trials may not be motivated to search exhaustively for potential side effects…Second, many trials do not state clearly how and how often adverse effects were assessed…”

This is a really important caveat. Other researchers have noted that “myopathy” (muscle pain, cramps and weakness) has been defined in all sorts of different ways in statin clinical trials. In some cases, it was restricted to enzyme elevation. In other words, a patient might suffer pain, but if their enzyme levels were within “reasonable” limits, this might not be counted as actual myopathy.

An article in BMJ (October 22, 2013) noted that “the prevalence of muscle pain in statin users is 50% greater than in non-users. In absolute terms, this increase in muscle pain is 100 times greater than that reported in clinical trials…”

Put another way, the gold-standard randomized controlled trials that were analyzed in the article making headlines this week may not have collected accurate data about muscle pain and weakness. The authors even admit that such studies may have underestimated the true incidence of new cases of diabetes attributable to statins (1 in 5 patients). As they point out, “This means that, of all new diabetes diagnoses on statins, 20% were directly pharmacologically attributable to statins…[though] new diagnosis of diabetes was only documented in three of the 29 trials.” Read between the lines and you will immediately realize that this serious complication of statin therapy was completely missed by the vast majority of clinical trials.

This has been pretty much ignored or glossed over by the media. One of the authors, Ben Goldacre, points out some of the caveats that should be taken into account on his blog.

People’s Pharmacy Analysis:

Randomized clinical trials, especially those designed to obtain FDA approval, are not set up for detecting adverse drug reactions and they don’t do it very well. They are really designed to demonstrate drug effectiveness rather than risk. A little-realized fact about such trials is that the way in which side effect information is collected may actually affect the study.

This was revealed in a landmark report by Jerry Avorn, MD, and his colleagues in a fascinating study titled: “Differences in Adverse Effect Reporting in Placebo Groups in SSRI and Tricyclic Antidepressant Trials: A Systematic Review and Meta-Analysis” (Drug Safety, Nov. 2009). Dr. Avorn and his co-authors concluded that:

“Conclusion: Adverse effect profiles reported in clinical trials are strongly influenced by expectations from investigators and patients. This difference cannot be attributed to ascertainment methods. Adverse effect patterns of the drug group are closely related to adverse effects of the placebo group. These results question the validity of the assumption that adverse effects in placebo groups reflect the ‘drug-unspecific effects’.”

In other words, the side effects reported in the placebo groups were seemingly affected by the kind of antidepressant being studied. If the drug itself caused dizziness, constipation and dry mouth in a high proportion of patients, the people getting the placebo in that trial magically had a high incidence of dizziness, constipation and dry mouth.

The conclusion doctors might make would be that since the symptoms were similar for both the placebo group and the drug group, there is no difference between them. But this is a trap. By comparing the side effects experienced only by people taking placebos in antidepressant trials the truth was revealed. You would imagine that people getting inactive placebos for the same condition (depression) would have similar side effects. But Dr. Avorn’s study shows that the placebo side effects vary enormously depending upon the type of antidepressant being studied.

We suspect that this may also be relevant for the current statin side effect analysis. If researchers influence side effect reports by the way they ask the questions or collect the data, it may be more difficult to determine the true incidence of adverse reactions to statins. We find it difficult to imagine that statins actually have no side effects. What do you think?

Here are some complications listed in the official prescribing information:

STATIN SIDE EFFECTS:

Headache
Muscle aches, muscle cramps, muscle pain, spasms:
(anywhere in the body, including legs, shoulders, back, arms or neck)
Fatigue, weakness
Arthritis, joint pain, joint stiffness
Abdominal pain, digestive upset, nausea, diarrhea, flatulence
Blood sugar elevation, diabetes
Sore throat, flu symptoms, sinusitis
Dizziness
Itching, rash, hives
Liver damage, liver failure, kidney damage
Insomnia, sleeping difficulties, nightmares
Forgetfulness, memory problems, amnesia, confusion, cognitive dysfunction
Peripheral neuropathy, nerve tingling, nerve burning
Pancreatitis
Cataracts
Sexual problems, erectile dysfunction, low libido

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About the Author
Joe Graedon is a pharmacologist who has dedicated his career to making drug information understandable to consumers. His best-selling book, The People’s Pharmacy, was published in 1976 and led to a syndicated newspaper column, syndicated public radio show and web site. In 2006, Long Island University awarded him an honorary doctorate as “one of the country's leading drug experts for the consumer.” .
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My HMO had me on 81 mg of ASA, placid and simvistatin following stent surgery. I developed muscle problems so painful that holding the paper to read was difficult. I went to my doctor to complain about muscle problems. He prescribed Naprosyn which was yet another blood thinner which blew out a artery in my colon and sever bleeding put me in the hospital where a surgeon cancelled my colonoscopy and removed my entire colon. The pathologist found that I had a spontaneous bleeding artery which should have been cauterized and I’d still have my colon. I’m now having twenty five BMs a day now and housebound. Any one have anything like this and have suggestions?

After a heart attack in 2010, my cardiologist prescribed 40 mg of Zocor (simvastatin) daily. I am 78 and have been taking this statin drug for 5+ years. During this time, I have developed the following symptoms: heat intolerance, short term memory loss, leg muscle weakness, imbalance, peripheral neuropathy, numbness in feet and foot drop. I attributed these symptoms to the aging process until I began researching on the internet and discovered that they are the side effects of statins. I blame the Food and Drug Administration, the American Medical Association and the Pharmaceutical Manufacturers of America for not being honest and transparent about the dangers of taking statins. Why didn’t they do their “due diligence?” I can’t imagine why these side effects didn’t show up in double blind drug trials. My main concern now is trying to reverse the side effects of taking a statin drug for 5+ years. Perhaps someone with a legal background should consider a class action lawsuit. However, be forewarned that you are going up against powerful, wealthy and influential organizations.

It only took 12 weeks for adverse effects to begin to affect my life. The first occasion was moving back to Oklahoma from Alaska in 2004. I was in private practice but the exhaustion was terrible. Muscle pain, back pain and weakness were causing problems in getting to work, staying focused and trying to appear as attentive as possible.

No one knew what was wrong because tests were all normal. One man, a Native American doctor was sure that I was “allergic” to the statins that had been prescribed and told me to stop them. I improved but continued to have pain and weakness that was intermittent. I was also depressed and blamed that on stress, the move, etc., etc.,…

The second time I had to have a stent in my heart and when I told the doctor that I was “allergic” to statins he told me that the medicine did not do that and if I didn’t take them I would die. I didn’t want to die so I took them for 4 months. However, this time the deterioration was very fast. Extreme muscle pain, weakness and crying was overwhelming. I lasted about 6 months and my sister and brother-in- law moved me to Michigan because I was unable to work.

It has been 6 years since I stopped the statins. The condition has not improved. I work with a pain management doctor; muscle weakness continues to increase and tremors are beginning to be annoying. Neuropathy has now covered all toes and the numbness is causing me to have difficulty with balance. This medicine destroyed my hope. I get great support from my group of statin affected people. If it weren’t for them I would have thought no one else was affected as I had been affected. So glad more infor is coming out!!

I could not believe I was really reading this–there are no side effects to taking statins. How could anyone be allowed to print such an article that is full of lies? Seven years ago my doctor put me on 80 mg. of Lipitor. I took this for 4 months, and when I went back to the office at that time for bloodwork, my CPK which had been in the normal range ( 25 – 147) had gone all the way up to 11,000. My muscles were so weak I could barely climb steps or get up out of a chair. I could no longer lift my grandchildren. The doctor, of course, stopped the Lipitor immediately and sent me for a Liver Biopsy thinking that I had liver damage. Well, that biopsy came back normal, and those doctors suggested that this was probably muscle damage. Initially my CPK slowly went back down over the next 3 years or so, but then all of a sudden it started going up again, all the way up to 9,000. At that time I finally decided to have a muscle biopsy done by a cardiologist, and it clearly showed that I had necrotizing myopathy due to taking a statin! There is no “cure” for this disease, but I have been getting IVIG therapy for 14 months now to stop my muscles from destroying themselves, and that has brought my CPK down to 1400 or 1500. A lot of my strength has returned, but I’m still not back to normal and I probably never will be! I think everyone that says there are no side effects to taking statins should be put on them and made to take them for a few years. Then let’s talk about side effects!

Sept 2014
I started taking a statin several years ago (at least 4) for cholesterol. I am overweight and often have muscle and joint pain. But i work full time and im on my feet all day. Cholesterol consistently stayed high.

Last year after a type 2 diabetes Dx. I changed my way of eating and my (second blood work 6 months after new way of eating started) blood work showed my cholesterol , triglycerides and A1c in normal range along with some weight loss. My. Dr. did not want me off the statin though. For my health.

My muscle and joint pain, increasingly got worse. I started having muscle spasms and cramps like a Charlie horse in my upper back/shoulder blade area and arm along with neck, elbow, knee and smaller joints pain, fatigue and anxiety. I had EMGs and EKGs, done and it was determined I have pinched nerves, and herniated discs. Thankfully no heart problems. I started PT. And it helped a bit but not completely. PT ended and life went on. Then my face went numb and a brain MRI was ordered. They found white spots on the brain MRI that could be the start of MS but could also be a result of previously having Diabetes, high cholesterol and headaches. I have a follow up with the neurologist in 3 months. I need to chart my symptoms.

After reading posts online I stopped taking the statin Aug. 14 I made an appointment and asked my primary Dr if I could stay off the statin? the answer was yes. It has been a week off and I have not had one severe muscle spasm. I have a lot of muscle pain, weakness in my legs, back, arm, severe hip pain and a continued feeling of buzzing in my abdomen and thighs… I have muscle twitching and shaking still in my back and arm sometimes also. I am feeling a lot of anxiety and fatigue. I was placed on a anxiety med and also given something to help me sleep.
I have to wonder out loud if the statin has played a roll in my muscle cramping and pain. Is this a symptom others have had after taking a statin?

If after taking the anxiety med for 4 weeks I am still feeling “MS” symptoms my primary will send me for a second opinion with a different neurologist for further testing sooner in Boston.

I started taking CoQ10 also. What type of Dr. Would diagnose and or treat issues related to statin muscle damage?

My husband was on fenofibrate and Niaspan. Over time he began falling down frequently, became borderline confused, had slurred speech, and had loss of hearing in both ears. I talked to his cardiologist, took him to neurologists, his primary MD and a eye, ear guy. No one found anything wrong with him. He was reaching the point where even with a walker he was falling. He was going downhill so quickly, I was convinced he was dying and no one could tell me why. I did not feel like anyone was listening to us. We had the impression that the physicians thought we were idiots. He takes a lot of different meds for his cardiac issues and the only drugs I felt comfortable taking him off of myself were the cholesterol lowering drugs. The cardiologist was not happy. But, after a couple of weeks to a month, I noticed he wasn’t falling anymore, his mind was much clearer and his speech was no longer slurred. His cholesterol has remained within normal ranges. I do recommend that prior to taking the step to stop meds you should speak to your physician.

Go to the Myositis Clinic at Johns Hopkins in Baltimore. They were such a help to me!

I have been trying to make sense of all this “data” without any conclusion. I started taking Zocor, 20 MG, in 1994, then was switched to 40 MG about a year later. I had a mild TIA (stroke) in 2002 and started walking my dog 45 minutes (instead of 20) every day and also lost a lot of weight – down from 205 to 175, but my cholesterol stayed about the same – total was about 115.
No more strokes, never any heart incidents, I have had cardiologist administered stress testing about every 5 years. Always passed fine.
Since I’m now 77 and my cholesterol is good (total about 100) with daily 20 MG Zocor + 1000 mg niacin (switched in 2012), my main complaint is neuropathy (numbness, needle prick feeling) in both feet, more in the left foot. I also have memory problems, but, as I said, I am 77. I now am down to 160 lbs. I wondered why I don’t have leg cramps, can it be because I walk every day instead of maybe, jog.

my dr went to a site in front of me and said my side effects were not on there, now they are, he did a drug screen because he didn’t believe the crazy side effects I had, years later they came out, 2 drug companies own lawyers later told me, every thing I told them was true, one said “no one over 50 should be on cholesterol meds” and some other suff. I wrote a book of horrors so my family would have a record of my mental nightmares, of the troubles and money, I lost jobs and money over 100,000. Could not work I was so sick…every one I know who took statins, had the same troubles depending on mg. I now suffer 8yrs off, with muscle weakness so bad it’s unreal, the book don’t even start with all the troubles I suffered. kb

I have been taking Simvastatin since, 2008. Since then, I have been experiencing unbelievable muscle pain/cramps in my leg and, feet. After reading other user comments regarding this drug on webmd as well as on here, I am convinced it is the Simvastatin that’s causing the muscle pain. So, I’ve decided to stop taking it because, the muscle pain I’ve experienced is just too much to bare.

After six weeks on Crestor, I would walk up a flight of stair in so much pain in my heart that I thought I was having a heart attack. I was so out of breath that I couldn’t talk to my customers. I credit Crestor with damaging my pulmonary artery in my heart and causing Pulmonary Hypertension (PAH).

I have taken two different statins in the last six years. I suffered cramps in areas of muscles that I never would have expected. In my arms, my neck. Even my facial muscles. I stopped taking the first statin on my own. After about ten days the cramps stopped. My Dr. prescribed a different statin. Same result. Cramps again. Stopped on my own two weeks ago. I am again cramp free. Another Dr. prescribed Crestor. I do not intend to take this statin. Can’t understand this love affair doctors have with statins. I now love MY life without statins.

My husband took Lipitor 10 mg/day for 4 yrs for a mildly elevated cholesterol level. He was a daily runner, a marathoner and worked out at the gym 5 x/week. He has profound Parkinson’s disease we both attribute to Lipitor.
He possesses mutations in 2 genes responsible for the movement of statins into the liver for phase II detoxification. These genes are not rare, one occurring in 24% of the Caucasian population. Plasma statin levels in these individuals with the risk alleles who take statins were discovered to be toxic levels. The lucky ones developed severe myopathy and stopped the statin. My husband developed a progressive neuro degenerative disease.

After reading all of the above comments, and especially the last one from Chris, it makes me wonder how many millions of dollars we spend annually just chasing down the cause of these horrible side effects. Yet, the answer is right in front of us the entire time.
Chris, you do not state why you take Crestor, but I encourage you to find a different doctor to review this. After many years of taking various statins (all with a number of side effects) simply due to her “high” total cholesterol number, a doctor finally ran the risk calculation number for my wife. She wasn’t even close to the threshold for statins. Off them now, and I doubt she would ever go back on them.

It is March 20th, 2014. I have been battling Vertigo, dizziness, withdrawn, confusion, lack of cognitive ability, depression, muscle aches and outright want to die attitude for nearly 3 months. I have been to a family DR., therapists, neurologist, ENT specialists. Have had CT’s MRI’s, and you name it have probably had it. Had an episodic event that looked like the onset of a stroke which the MRI indicated no brain damage but possibly a TIA.
Neurologist at the Cleveland Clinic disputed this on my follow up and told me possibly High Blood pressure maybe causing all of this. Self monitoring for over a month indicated minor elevations after having been on Crestor for many months. But ever since I have been on Crestor the side effects have been as mentioned above. Especially overall lack of well being. I quite simply FEEL TERRIBLE, no desire to do anything, dizzy all the time, withdrawn, confused, cognitive function lowered, no motivation, achy muscles and high level of mood swings.
I AM CONVINCED CRESTOR IS DOING THIS. MY DR IS NOT. I may need to find a new Doctor. All my reading indicates Lose Weight, eat natural, cut out all the synthetic drugs and get off the Grid. Imagine that!! Guess it is time to at least try some of this.

Never, Never, will I take a statin. Even the most smallest, tiniest milligram of a pill makes me sick!
The muscles will never be the same after I took that first batch. Don’t believe these “scientists”, it’s bull___!
I am 66 years and I want to be older and healthier and I know I can do it without statins!!
By the way, love all the healthful info you give us. Thank you thank you!!

OMG I can’t believe I just found this. I was just discussing this with a friend earlier today without even knowing this article existed.
I have a suspicion that after taking Lovastatin for 5 yrs that this drug is backfiring on me and hurting me instead of helping. I have been experiencing pins and needles feeling in my feet and legs for at least a year or so that I can remember. I mentioned it to my previous neurologist believing it was a nerve issue not a drug issue. Nothing was done and it was kind of dismissed. 6mo ago I suddenly experienced SEVERE pain and tingling in both my hands AND feet. I was in so much pain it would wake me. Another doctor tested me and said I have neuropathy or the beginnings of it. He wants me to have a blood test and see him in a month. In the meantime I was doing reading on Neuropathy and an interesting this is that it said Statin drugs can cause that.
I need to bring up this issue with the doctor and hope he will agree with me or at least be willing to try to take me off the drug for awhile. What can it hurt? I’d be willing to try a non statin drug.
Are there any non statin drugs?

Joe and Terry,
Thank you so much for all the information you provide to help people without causing potential harm to our health.
In 2009 I started Lipitor and had no immediate side effects. In 2010, I moved to another state. I had started having difficulty performing my job as a TSA Officer. When I had to hand wand or pat down a passenger, I had trouble standing back up due to lack of strength in my legs I had no idea what was causing this.
Around the same time, I had a neck injury and was being treated by a Chiropractor. Since they correct the whole spinal area, he was having less success than he expected, he asked what medications I was on. As soon as I said Lipitor, he told me I needed to add CoQ10. I researched this and the side effects of statins.
I started the CoQ10 and stopped Lipitor. My muscle strength came back completely with in 2-3 months. I believe I would have been in a wheel chair eventually if I hadn’t stopped the statin.
And now I know more about the importance of Cholesterol thanks to you and some others who study effects on the brain.

@K.R.B. I am so sorry to hear of your problems. What really bugs me is that you were evaluated by what are supposed to be the top specialists in the country, and I suppose they never thought once, to consider any medication you are taking as a potential cause or at the very least a contributor to your condition..A simple google search revealed several references to statins causing/unmasking Necrotizing Myositis. But many doctors are too proud or arrogant or ignorant to consider an RX as a causal contributor, Here is one I found on a pubmed search
CONCLUSION: Statins have recently been associated with a variety of inflammatory myopathies including polymyositis, dermatomyositis, and a necrotizing myopathy. The association of statins with necrotizing myopathy is strengthened by the discovery that the serum of some of these patients contains an anti-HMGCR antibody. This suggests that statins can cause or unmask an immune mediated myopathy.. http://www.ncbi.nlm.nih.gov/pubmed/22154355
Another is entitled “Statin Use Linked to Rare Autoimmune Muscle Disease, Study Finds”
http://www.hopkinsmedicine.org/news/media/releases/statin_use_linked_to_rare_autoimmune_muscle_disease_study_finds
What makes me sick in this Hopkins website, they note “Johns Hopkins researchers discover how cholesterol-lowering drugs can cause body to attack its own proteins; caution patients not to fear popular medication” I question if there feelings would remain if it were there own dad, mom, spouse.
Again, I am so sorry to hear of your medical problems. It really hits home for me, as my father is 72 as well.

When you read the most common side effects of statins (especially the muscle pain) what is the human reaction to every motion being painful? Obviously, it’s to sit down and stop moving except for what is absolutely necessary. We KNOW that being sedentary is a HUGE risk for heart attack, stroke, etc. How can statins NOT be seen as a risk factor?
It’s all in the lying-with-statistics thing. When a statin user stops moving to avoid the pain, the statisticians “correct for” the “lifestyle choice” of being sedentary and the “lifestyle choice” of being obese. And then attribute the heart attacks and strokes and diabetes to the patient becoming inexplicably stupid and CHOOSING to be disabled and it having nothing at all to do with the drug disabling them.

That is exactly what happened to me. I have that gene, that indicates that I cannot tolerate statins. Of course they do not test for it before they put you on a statin, and as a result I acquired necrotizing myopathy! I’m so so angry about this!

At age 72 I was in very good health. I had been taking Simvastatin for many years prescribed because of supposed cholesterol issues. 2 years ago, my thighs became extremely stiff and weak. My condition worsened until I became so weak that I could no longer live alone. Luckily, lengthy treatment at Mayo Clinic got my auto immune disease called necrotizing myositis under control. My rheumatologist at Mayo told me that one tenth of one percent of the U.S.A develop this annually. She was adamant that I NEVER take statins again. Interestingly, I have now been off of statins for two years and my cholesterol level has remained within normal levels.

I am a male, 83 years old and I would rather die, while feeling alive, than to live feeling half dead. My psa test went down 6 points, and my Doctor was very excited. He wanted to know what I had done. I told him I quit taking simvastatin, and he said, “You don’t want to have a stroke do you?” it is not only my appraisal of my well being, but other people have commented on my energy such as walking and movements. I look better and feel better since rejecting simvastatin. Lloyd S.

@ JimR Excellent point and article! Odd, how an article interprets a study, which is completely different than the ACTUAL data…$$$$$$$

@maustin I was on the lowest dose of Lipitor, 10mg…and am now disabled going on 12 years…2 of the most knowledgeable experts in the country, Dr Beatrice Golomb and Dr Doug Wallace of UC Irvine, have implicated my statin use as the cause of my Mitochondrial DNA mutation as well as the Apoptosis (Brain Cell Death) Count yourself lucky that you have not suffered a horrible effect, YET…And I can assure you if you ask your physician, they will preach what they are tought my the DRUG REPS, that if you want to live, walk on water, fly etc…you must not stop your statin….RUBBISH!!! You have any idea how many people die each year, by listening to doctors orders?

Eight years after my husband started mevacor, he died from ALS. If only we had known. I began lipitor, after an angioplasty because of a large blood clot, in 1998. Was told I would be on it for the rest of my life. Four years later I had my thyroid removed because of cancer and lost my parathyroids during the surgery.
I began to decline, had to go back to insulin for diabetic control, got three more cancers. One day as I was putting my pills together for the week, I looked at the lipitor and my gut told me to drop it. My blood sugars also dropped, out of nowhere and in a few days time I had decreased my insulin by a third. Since then I have lost about 40 pounds, up and down another five, with no change in my diabetes.
I blamed my decline on the thyroid surgery, but in looking back, since I have been reading about statins here, I realize it began with the lipitor.
My fibro flared, my thinking abilities suffered and then after defeating cancer, tho I lost a kidney, I began to suffer with spinal stenosis. I am having a bad old age, started with the lipitor and was further influenced by the other health issues. It hurts to move, I depend on pain medications, steroid shots and courses of prednisone, as well as too many other pills.
I have memory issues, have lost at least half of my short term memory, as well as the same amount of hair, my fingernails may be following. My total cholesterol is 318, my HDL 99, and that is fine with me. I have no heart disease in spite of a family history, and high cholesterol except for the 12 years on lipitor.
I cannot help but wonder if I had refused lipitor, would my diabetes stayed the same? Better control of diabetes, without insulin, less weight gain, less inflammation, less cancer? A better today? I am glad that this site reaches so many people, searches for the truth, and empowers many to take their health care into their own hands.

My husband has been through the same problems mentioned in these comments and finally refused to take any more statins. Because of severe leg pain and cramping, he was unable to walk more than 10 steps, and then had to stop, rest a minute, take 10 more steps, etc. He also had spinal stenosis so it was confusing as to what was causing his problem. He stopped taking statins (tried them all) and he had successful back surgery. For about a month, he was doing very well, slowly healing and increasing his activities and walking. When we felt his strength was returning, the doctor suggested he try Fenofibrate for his cholesterol/triglycerides control. After one month, the numbers improved drastically so he has continued taking the medication.
However, his pain has now moved to his hips, sometimes, travels from one leg to the other and he can’t walk without hanging on to the wall, chair, etc. Numerous tests have been done without an accurate diagnosis. He is becoming lethargic, slow in his mental responses, forgetful and still unable to walk. His kidney function has diminished and now they want to run more tests.
I feel it is the Fenofibrate. My questions is: Has anyone had any similar experiences with this drug? I know it is not a statin, but can it have the same side effects?

Perhaps it depends on how much you take. I have been taking 10 mg of Pravastatin for a couple of years and have had no side effects. At first, my cholesterol went down, but now it’s back. Dr. wanted me to take more mgs. and I said, “no”. I realize that I need to watch my diet, so I’m working on that.

@Marilyn re Zetia….Zetia reduces cholesterol absorption in the gut to stop absorption of cholesterol from the foods you eat. ZETIA HAS NEVER BEEN SHOWN TO PREVENT HEART DISEASE… Per Pubmed:EXPERT OPINION:”Simvastatin has been clearly shown to decrease LDL-cholesterol, which is associated with the slowing of atherosclerosis and a reduction in cardiovascular morbidity and mortality. Ezetimibe alone or in the presence of simvastatin lowers LDL-cholesterol. However, ezetimibe alone or in the presence of simvastatin has not been shown to have any irrefutable beneficial effects on atherosclerosis or cardiovascular morbidity and mortality. Thus, until/unless the use of ezetimibe is clearly shown to improve clinical outcomes, its use should be largely restricted to clinical trials investigating clinical outcomes and should not be used routinely in everyday practice. http://www.ncbi.nlm.nih.gov/pubmed/22725704
Statins Lower Cholesterol by blocking the Acetyl CoA Reductase enzyme from producing cholesterol which in turn blocks production of Vitamin D, Testosterone, Steroid Hormones, Dolichols, CoQ10, etc which are ALL ESSENTIAL TO LIFE.

I experienced muscle pain while on lovastatin. I asked my doctor to discontinue it, and off it, I had considerably less muscle pain. I am on another non-statin medication. jm

“Figures don’t lie but liars can figure!” I had been on simvastatin for many years as it was considered a miracle drug. About the same time I started taking a statin I was diagnosed with Type 2 diabetes. I have no way of knowing if there is a connection but more and more evidence is leaning that way. About six months ago I stopped taking simvastatin and have noticed my hips and knees are feeling better.
My latest lab results from a month ago show an increase in LDL to a bit over Standard Range. HDL remains well within Standard Range. I had also experienced general sexual problems but I attributed those to paroxetine.
I stopped taking the paroxetine about two months ago and the sexual problems have completely disappeared! I don’t know if the statin contributed to this but I feel better overall after eliminating both drugs. Funny that a person can actually feel better going off drugs that are supposed to make you feel better! I suspect the only people who feel better when we take many drugs are the drug companies.

Currently taking Pravachol with no adverse effects. Lipitor cause severe muscle cramps for me..and Simivistatin made it feel like a sledge hammer was hitting my knee.

Hi
I am sorry you were so sick but did you ever take Cipro, Avelox, Levaquin or Floxin or one of any of the antibiotics in the Fluoroquinolone group? This does it to you too and perhaps both the Lipitor and the FQs did a job on your body. I would look into it. The FQs don’t necessarily give you the ADRs immediately. It can take months and months and sometimes years to rear it’s ugly head. Feel better and good luck.

They say the same thing about Fluoroquinolone drugs. Cipro, Levaquin, Floxin, Avelox just to name a few.

I have been a runner for over 30 years (age 61 now). Five years ago my doctor recommended a Lipitor regimen to reduce my cholesterol count. After taking this medication for about a month my hips hurt so badly that I could not walk fast much less run. I stopped taking the Lipitor and within two weeks the hip pain had disappeared.

Zetia is a cholesterol lowering drug, is it a statin and does it have the same side effects?
People’s Pharmacy response: Zetia is NOT a statin. It does, however, have some similar side effects, including some muscle soreness.

I am now nearly 83 yrs old. I took Zocor for about 1 year in 2001-2002, pushed, by not only my Cardiologis, but pushed by all the internists at that time. I don’t think there were any statin ads on TV. at least, nothing about muscle weakness. My muscles got so weak that I could not step up one step alone.
My brother, who was 15 yrs older was having no problem with his step. I have and had an active life, aerobics, golf, tennis etc. I finally decided that it must be the Zocor. I refused to take it or any of the statins.
I met lots of people at the gym, that were there because of statins. Some with canes, others in walkers. My biceps were shot too. IN 2005, after, I had gone off the statins for a few years, I developed back problems and had to have surgery. Thank goodness, I had a great neurosurgeon, I have had no side effects from that. With much therapy, my biceps and leg muscles began to come back slowly. They are not yet as strong as most of my healthy friends.
I try to play at golf, a bit now and try to get to the gym & water aerobics a few times a week. I still cannot go up and down stairs without a banister. I have trouble getting up off the floor, so do not get on the floor and play with my great G children. My triglycerides are a bit high, 300+/-, my total cholesterol is the same as it was 15 yrs ago, but they lowered the normal stats. . My HDL is 60. I should have longevity genes. The NIH etc. did not list weakness, as a side effect, when i began taking statins.
About 6 years ago I met a Pharmacoogist?, not a pharmacist, who advised against them. I had friends who got diabetes, on blood thinners for leg thrombosis, statin? BTW, the med profession is pushing BP meds on my 80 yr old friends, who have BPs of 125/80. They are having side effects. I am on BP meds, they do control it, but I have had some disastrous side effects with them too… My brothers have had their BP get down to 115/55, they get dizzy and the Dr will not change it.
In passing, I was Med. Technologist, and I have & had many Dr’s in my family. They are and were conservative with meds. I really appreciated your program on generics. You people do a great job, I have listened to you for many years… One of our top Cardiologists, spoke to our senior group last week and still feels that Statins are needed more than they are taken. He did say that genetics is prob. about 80% of it, and also rec. the better diets + exercise. This is really long, and I feel really strong about this subject… I am sure that they help an occ person. I am happy for exposure to dangerous meds. People see ads on TV and believe them. So sad!

I will stay under Dr care & follow my heart. I too took Statins for 3 years until legs became so sore and below knee down to ankles felt like nothing Id ever. I felt before such a dead feeling and mobility was lacking I also had stomach troubles I changed pills (Statins)3 times and was finally put on 2 statins I felt that this was not right I had my blood checked and my liver # was too high.
So I quit and became vegan and yup that’s dairy free too. I am not into exercise but keep very active. I don’t drink smoke and just drink water and soda water low sodium it took awhile but Id rather give up things and do things as natural as I can unless of course one really needs meds in certain cases But this is all a money making thing Drug co are starting to sweat Glad the general public is smartening up and keeping their eyes and ears open. Too bad we cant trust these days Money. hmmmm

I too was put on a statin for my Cholesterol & Triglcerides (20mg Pravastatin) I was on it for only 6 months, but I couldn’t sleep, muscle pains, weakness in my legs and arms and I have been off of it for almost 2 years and I still am not back to normal. I had a hard time convincing my doctor of all the problems I was having and he wanted to blame it on arthritis, but I knew better.
Something had to be wrong from the pills as before I started taking them I could run at the drop of a hat, did all my yard work, gardening, housework, fishing and hiking. I was extremely active, but I almost ended up in a wheelchair before I got off of them. I am still hoping to get back to all the things I did before, but I have my doubts because of the pain I experience whenever I try to do so many of those things. Life is no fun anymore plus I feel physically ill a lot of days.
Please, if a loved one shows any changes while on a Statin, get them to a doctor immediately to stop the ststins!!!

EXCELLENT INVESTIGATIVE ANALYSIS BY THE PEOPLES’ PHARMACY STAFF!!! Great rebuttal based on scientific analysis of the clinical analysis model used… most impressive! Let me count the ways in which we “consumers” depend on the non-biased, honest and thorough research methods that are used by the wonderfully intelligent staff working at the Peoples’ Pharmacy!
Thank you,
Stephen A. Otto, ED.S.

This is all about MONEY

All I know for certain, is I was a healthy 30 years old when I was prescribed Lipitor (all statins work the same way) When 1 year later, developed sleep apnea, then 2 years later, I developed neuronal apoptosis (holes in my brain from the neurons dying) I had a brain biopsy revealing a Mitochondrial DNA mutation similar to MELAS (Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-Like Episodes. For 28 days, I was inpatient at the University of Wisconsin, Hospital in Madison, I was like a patient with alzheimers, I could not walk, nor speak coherently, I was incontinent of Bowel and Bladder, I did not know my family (wife, Parents, siblings nor my 2 year old son.) I was evaluated by every neurologist, med student, resident in the neurology department. Differential diagnosis included New Variant Creutzfeld Jakob Disease (Mad Cow Disease), MELAS, and my favorite, Viral Encephalitis. EEG, MRI, CT Scans, lumbar puncture,Brain Biopsy, Muscle Biopsy, multiple labs etc nearly $300,000 in medical care over these 28 days, days away from transferring to a nursing home. I was evaluated by a visiting professor from Harvard who suggested I start a mitochondrial cocktail (essentially 12 vitamins, amino acids, and CoQ10, within a few days I improved to the point where I could go home with aggressive Rehab therapies, PT, OT and SPeech. Within a few months I tried to go back to my career as an RN, but after I tried, I was approached by my boss who informed me that my work thought processes were not consistent with employment, went home tail between my legs, and at next neuro visit, had an extensive Neuro-Psych eval, which determined that my cognition was very slow, severely impaired short term memory, severity was enough to seriously impair any substantial gainful employment. A couple months before this, my wife and I saw Good Morning America, where Diane Sawyer was interviewing Dr Beatrice Golomb, of the UCSD Statin effects study, my wife begged me to enroll, I told her that my prior 11 years as a Critical Care RN there was no way Lipitor had anything to do with my illness. I knew everything there was to know about this drug, and there was no way. But in order to maintain my marriage, I would enroll. Well when the study was concluded some time later, I received a call from Dr Golomb, sharing with me that I was one of several patients in her study, with similar biopsy findings, etc…I was FLOORED! Thinking of the hundreds of patients I must have given these drugs to..I remain disabled to this day, which will be 12 years in October. I do not think a placebo or any other kind of non chemical would cause my problems. I urge anyone prescribed these drugs to do so VERY CAUTIOUSLY! As this was not in the brochure.

My son’s insurance company decided he should be taking Zocor for high cholesterol instead of the generic drug his doctor prescribed and which he had taken for five years.
Within a few weeks after switching to Zocor, he developed acute pancreatitis, spent 10 days in ICU and had lost 80% of his pancreas, making him an insulin-dependent diabetic. He had a 2nd near-death experience 3 months later when they attempted to drain the pseudo cysts that developed from the pancreatitis. They couldn’t stop the bleeding and he was given 11 units of blood.
Then 6 months after that he had to have his gallbladder removed since they couldn’t be sure that gallstones hadn’t plugged the pancreatic ducts and he can’t risk getting pancreatitis again.
I blame all of this on the statin drug Zocor. The public needs to be better informed and not depend on these so-called studies to provide the facts.

Seven years ago I was placed on Plavix and simvastatin five days after a TIA which resolved itself in less than a minute. However, five days later the doctor gave me these pills and said they might cause me to have pain in the leg muscles etc. but to keep taking them for at least three weeks and that it would get better. That is what I did. Each day I took them I was tired and more tired. I could barely breath and I was severely weakened and could barely make it up a set of stairs let alone carry my art supplies. Finally one night before I went to bed I looked at the pills and realized that if I took one more pill I would die. So I stopped the simvistatin and each day I was off of it I felt better than the day before.
Later I stopped the plavix as well. I am a hearty person and rarely complain. But these two pills brought me to my knees.

One other unexplained problem my wife encountered that is possibly attributed to her years of statins: lichen planus. There is limited research on it’s link to statins, but interesting to note that somebody wondered about it enough to do the work. Unfortunately, unlike the insomnia, joint pain, “fuzziness”, leg rash and peripheral neuropathy, this one did not go away when she quit taking statins for good.
I have not, and will not, ever take a statin.

I’ve been on low dose statins about 10 years and have little trouble with them (perhaps because I also take CoQ10 and B12). Lately, I’ve been on 40 mg Pravachol. Because the anecdotal correlation between statins and ALS worries me, I’ve taken them only sporadically for the last year or so. A couple of weeks before pre-physician visit blood tests, I go back on them so my cholesterol looks acceptable.
Last month I resumed the statin regime and almost immediately started experiencing extreme fatigue, brain fog, memory problems, and slightly spastic movements. The brain fog manifests itself as speech problems, which is unacceptable for me especially because I do considerable public speaking. Right after the blood tests I dropped the statin and doubled my CoQ10 and vitamin D3, which I was low in. Within a week, those symptoms had abated.
I believe there are some efforts to include statins in commonly eaten foods. This effort has gained some traction in England, particularly. In my opinion, if journalists and public interest groups don’t reveal the side effects or at least the plethora of individual problems with statin use, then this potentially damaging drug could be foisted on the general public.
While Judyfbh is no doubt right about her company, from what I’ve seen drug companies don’t do a good job of revealing negative information about their products. They should be held to account on this and other drugs, and that account includes follow-up studies of users and more testing for problems. Ideally, we should also require drug companies to slow down the sped-up incomprehensible list of caveats at the end of commercials so that people can actually hear and understand the consequences of taking those drugs.

Many people put on statins are up in years – 50+.
Aches & pains are attributed to aging without regard for the actual cause.
How many here have shared that their doctors tell them this regularly?

Eye symptoms are also a part of the statin side effects reported in peer-reviewed journals. It is just not possible to make up symptoms such as ptosis that develop with statin use:
http://www.healio.com/ophthalmology/neurosciences/news/online/%7B77c0829e-6936-4b3c-9068-f81b8485dcde%7D/study-finds-link-between-statin-use-and-reported-adverse-ocular-reactions
http://onlinelibrary.wiley.com/doi/10.1111/j.1468-1331.2008.02234.x/abstract
http://www.ncbi.nlm.nih.gov/pubmed/10721974
http://www.ncbi.nlm.nih.gov/pubmed/18727677
Despite having developed this alarming symptom, along with the typical muscle pain and weakness, my endocrinologist is still trying to get me to take statins. My brother, who took them for a year, developed acute myasthenia gravis.

I had a 5-way heart artery bypass last year, a life saver at age 73. It was a shock to me that all these arteries were partially or completely blocked; I thought I led a healthy life-style. My cholesterol has been high all my life, but I didn’t worry about it since heart and diabetes issues are rampant in my family. Discussing this with the surgeon, he immediately stated it’s in my genes and the artery clogging probably started very early in life.
I was put on Lipitor after surgery. Blood tests afterward showed my cholesterol numbers plummeted. Had bad brain fog and took myself off the Lipitor — blood tests then showed the numbers had gone back up, although HDL was a satisfying 80, which I attributed to having an egg every morning. Went back on 1/4 the Lipitor dose (10 mg) and will have blood levels checked again in a month or so. Can anyone else relate to this?

The drug companies use placebos of their own choosing. So, are they using sugar pills or something else, that may cause similar side effects to the drugs. That information would be most helpful, to say the least. I have Post-Polio Syndrome, and there is no way I would ever take a statin that would cause more pain and put me in a wheelchair, like has happened to many other people who have PPS. Unfortunately profits matter, people don’t. Doctors can’t force people to take drugs that are harming them and causing severe side-effects, and if they are making you feel worse, you really can say no to them.

I have been a long distance runner my entire life, after going on Lipitor running has become a labor rather than the fun and stress relief I used to get from the sheer joy and competition. My legs no longer have the strength and endurance despite trying everything from the basics to extended workouts. I was even concerned blood flow to my legs must be my problem, tests proved there was no problem.
I am absolutely delighted to hear that my problem is all in my head, especially after being on the Reliability Program and handling classified information in my previous life for 30 years!

I have elevated cholesterol, and take a statin.
I have to disagree with some parts of your article. I worked for a pharmaceutical company and ran several trials for a statin. I cannot speak about other pharmaceutical companies, but the trials I ran were NOT influenced by anything. The adverse events were reported by all the doctors who participated in the trial and were recorded and compiled by the pharmaceutical company each time an event was reported. If an SAE (serious adverse event) is determined by the physicians to be serious enough to threaten the patient’s well being, the trial is discontinued and the drug in question is re-evaluated.
I have to disagree with your comment:
“Randomized clinical trials, especially those designed to obtain FDA approval, are not set up for detecting adverse drug reactions and they don’t do it very well. They are really designed to demonstrate drug effectiveness rather than risk.
A little-realized fact about such trials is that the way in which side effect information is collected may actually affect the study.”
How can the way the adverse reaction (AE) information is collected affect the study? Each physician independently reports the AE that happens in his/her office, and is not informed of AE’s reported by other physicians in the trial.
I don’t know how you can say that side effects are not reported, the list above proves otherwise.
I am not disputing the fact that statins have many side effects, as listed above, but they affect people in different ways. Some should not take statins, as they are affected adversely, but there are other people who do not have these side effects and statins help these people control their high cholesterol.

I have elevated cholesterol, and take a statin.
I have to disagree with some parts of your article. I worked for a pharmaceutical company and ran several trials for a statin. I cannot speak about other pharmaceutical companies, but the trials I ran were NOT influenced by anything. The adverse events were reported by all the doctors who participated in the trial and were recorded and compiled by the pharmaceutical company each time an event was reported. If an SAE (serious adverse event) is determined by the physicians to be serious enough to threaten the patient’s well being, the trial is discontinued and the drug in question is re-evaluated.
I have to disagree with your comment:
“Randomized clinical trials, especially those designed to obtain FDA approval, are not set up for detecting adverse drug reactions and they don’t do it very well. They are really designed to demonstrate drug effectiveness rather than risk.
A little-realized fact about such trials is that the way in which side effect information is collected may actually affect the study.”
How can the way the adverse reaction (AE) information is collected affect the study? Each physician independently reports the AE that happens in his/her office, and is not informed of AE’s reported by other physicians in the trial.
I don’t know how you can say that side effects are not reported, the list above proves otherwise.
I am not disputing the fact that statins have many side effects, as listed above, but they affect people in different ways. Some should not take statins, as they are affected adversely, but there are other people who do not have these side effects and statins help these people control their high cholesterol.

My husband was on statins for almost a year after heart stents. While on them, he started having some memory problems as well as muscle pain. He has been off them now for almost a year, but continues to have some memory problems. I can’t help but wonder if statins can sometimes cause long lasting muscle pain, even after discontinuing them, if they can do the same for memory problems and cause permanent damage in this area as well.

AND my precious daughter was placed on them twice AND had such serious side effects she immediately became so weak that she began to take serious falls. She now walks with a walker and always will need one. They are determined that everyone needs to take those horrible drugs. What a windfall for the drug companies and their investors.

Once again, as a Statin user, I must protest. Most of the complaints would be with the people, with or without Statins. I have great heart exams. My wonderful Nurse took me by the hand about 15 years ago and told me that with my levels of blood sugar I just had to start on Statins. The thing with Statins is that you must keep exercising. Light exercises, but every day, especially your legs. I am always grateful to my Nurse, and for Statins.
PS. The cramps are a problem, but bed soap, mustard, and pickle juice are a quick fix.
Best Regards,
Charles

This is why I never believe all the side effects listed on the prescription drug info!! I never had high cholesterol until moving to a different state where my new internist told me that because I had Diabetes Type II I was at twice the risk for heart attack and stroke.
He then put me on Simvastatin 10mg then upped it to 20. Immediately my blood sugar shot up on the average 10 points! When I got tired of trying to reason with the man, I changed doctors and my new doctor lowered the dose to 5mg.
My total cholesterol is 149(!)on that dose.. In addition, I have since discovered that besides causing muscle pain, etc. Simvastatin also makes one’s hair fall out – another side effect the drug makers don’t mention… I would like to throw out every prescription bottle in my medicine cabinet. Don’t listen to these studies!

My husband was on two of the drugs listed for years and years. He had the most severe muscle cramping you could imagine. He also had a cough that would NOT go away due to the lisinopril he was taking. He also had the digestive upsets and the night issues of insomnia. He was told by his doctor that he was pre-diabetic. Once he went off the drug, the issues cleared.
The very fact that one could POSSIBLY get diabetes from these drugs is reason enough to not take them. Take it from one who has lived with type 1 diabetes (totally unpreventable) for 42 years, you do not want to go there at all if you can possibly have a say in it. If, as a child, I could have done ANYTHING to prevent the diabetes from coming on, I would gladly have done it even before being diagnosed with it at age 10.
When I read articles like this, it just makes my blood boil. Diabetes is becoming diagnosed at alarming rates in this country and it is far from a nuisance like it is painted out to be. Try taking your blood sugar 5-10 times a day and administering insulin shots as well. Try watching every morsel you put in your mouth and wondering what effect your exercising will have on your blood sugar today. Stress and medication affect this disease enormously. No walk in the park here, folks.
Ridiculous in this day and age to not have pharmaceutical companies be more responsible in terms of side effects of medications. Don’t for a minute try to discount the side effect of diabetes. If something gave me diabetes, I would definitely sue the company that made the drug. End of story.

Several years ago my husband’s Dr. put him on Lipitor. When they upped the dosage he started having muscle issues and just didn’t feel very well. I am thankful that the issue seemed to clear up when he was taken off the Lipitor. He is now on crestor and welchol. We are gradually including coconut oil into our diet hoping it helps.

At least two physicians have written books which were about or included cognitive decline in statin users. Let’s don’t forget that.

I was on a statin for 2 years, and got so I felt someone had worked me over with a baseball bat. I had trouble getting out of my car.
A friend suggested I stop the statin- what a shock. I tried testing it 3 x’s with the same result- no pain, no jabbing pains suddenly in the legs, no ache-all-over.
My husband took statins for 4 years and slowly stopped hiking, stopped the daily Y exercising. I convinced him to drop the statin as a trial- inside 2 weeks he admitted he felt better, back to hiking and “Y” 3 x’s a week. That study is suspicious; the heck with cholesterol.

The question in my mind is whether we really need to lower cholesterol to the levels that the statin drugs bring it to. Our bodies need cholesterol for important metabolic functions. Cholesterol is an innocent band aid on the inflammatory process happening in the arteries.. The key is to lower the inflammation that triggers your body to deposit cholesterol. This is done through diet, exercise, lifestyle changes and supplementation… not a powerful drug that lowers your body’s ability to heal as well as perform crucial metabolic functions.

I took 8 different statins over a period of 5 years. In year four I began to get severe muscle cramps and my doctor tried another statin. It took from a few weeks to a few months to determine I could not take any statins w/o sever muscle cramps. There are side effects to some people taking statins.

I could write a long note describing my experience with statins and why I am absolutely certain that statins (I’ve tried most of the major brands) have caused severe hip pain and leg muscle pain and weakness. I can’t say I have experienced the broad list of other effects that I see noted in other comments. But I can certainly support what others have written about very serious muscle and hip weakness and pain.

Obviously none of the researchers have taken statins!!

Would it matter if the people reporting said how their insurance viewed them going to their Dr. with “minor” complaints like leg muscle pains? I am lucky to have no restrictions and can talk to my Dr. if I feel something is wrong (and I know my Dr. will listen and give me her valid opinion).

I’ve tried two different statins. The first gave me insomnia. I didn’t realize it was the statin that was causing the insomnia, so I was taking ambien to get to sleep. My wife suggested that it may be the statin. So I stopped taking it and was sleeping like a baby about two days later.
I tried another and that led to terrible muscle cramps in my legs. It came on gradually, it began with leg stiffness after sitting for a little while and progressed to terrible cramps.
After that I told my Doctor no more statins. If I can’t lower my cholesterol naturally, then I’ll live with it. My Doctor hasn’t argued with me because I do not have heart disease in my family, I’m not over weight, I do not smoke and I do not have high blood pressure. High cholesterol runs in my family.

I reported to my doctor periodic inexplicable cramps in my right foot, and a tender spot on my right hip as well as a sense of brain fog so that when writing I had to grope for words, in my judgement more than earlier. Was the brain fog age (I’m 69) or statins (taking 20mg pravastatin)?
The cramps I could live with, the brain fog less happily. My doctor suggested going on a 6 mo statin “vacation”. I started on Jan 1. So far, no cramps (they were receding anyway, so this is not a strong test), the tender spot which had been constant for at least a year, now rarely makes an appearance — maybe once a week for a few hours. The brain fog I think is getting distinctly better.
I have bad genes, very sensitive to dietary input, and even on a diet that only includes meat a few times a week as a small element in a complex dish, lots of nuts, no butter or cheese, and a fair amount of regular exercise, I suspect my LDL will turn out to be over 100. We’ll see.

I first started on Lipitor in 1999 and ended up almost disabled from the bone and joint pain. After that my drs tried various other statins all with the same problem just not as intense as Lipitor.
I cannot tell you how many people I have encountered with the same pain as I had while on Lipitor. They, too, stopped it and saw the pain magically disappear.
My last statin has been pravachol and even it causes me some pain. My heart dr a few months ago told me to just get off it. In my own opinion Lipitor should not even be on the market let alone the possibility of being sold over the counter.

My husband takes a statin drug and he’s suffering from eleven of the symptoms mentioned in the article. I’ve been telling him for months that I believe his symptoms are related to his cholesterol pill.
I’ve encouraged him to speak to his Dr. or the pharmacist about the side effects he’s experiencing but he won’t do it! I don’t know what to do for him; I’m tired of trying to persuade him. He reads the articles I print off and then throws them in the trash.
Does anyone have any suggestions for me?
Thank you.

The information is probably promoted by the pharms due to the fact they have probably pre-manufactured billions of these pills ahead of time and won’t know what to do with them!!! The true fact remains that real humans have tested and found fault and disaster with statins. If you think of all the people who have suffered and all those still being pushed onto statins, the overstock is really going to hurt the pharms budget if they can’t sell them off.

I’ve never taken sugar pills so cannot compare them to Crestor. However, I don’t think sugar pills would cause fatigue, muscle weakness and/or joint pain as Crestor.
With doctors permission I stopped taking Crestor just one year ago and gradually all these side effects have disappeared and the cholesterol has gone up only one point. A blood check is made every 3 months.

Bizarre…my late mother never experienced horrific leg muscle cramping, dizziness, insomnia, confusion, forgetfullness until her doctor prescribed a statin. While witnessing her steady decline, I attributed it to her age.
I now realize, it was her statin prescription. I will never take a statin after witnessing what my once vibrant, coherent, active senior mother, who walked two miles everyday, gardened, was completely aware of world events, could discuss any issue intelligently UNTIL she began her statin regimen. I will continue to maintain a good diet.

This is so sad that they never will admit what statins do. I was a very healthy, fit, energetic woman in my 40s in 2011. I started taking rosuvastatin [Crestor] as i have a genetic type 3 hyperlipidemia which was obviously not from what I ate as I am only between 7 and half stone to 8, 5 foot 1.
I have had 5 children and never had any other problems. After taking statins I had everything listed above including feeling like something was crawling in my ears. I was told it must be something else. What utter rubbish.
My research on here has helped me so much thank you all. I now take 2,000 b12 tablets every day with opti-omega 1,000 tg capsules for my triglycerides, vitamin d3 with calcium and magnesium and b6. I now nearly feel completely right except my left arm, which I struggled with so much. It’s 95% right now.
WHEN WILL THEY OWN UP AND STOP MAKING PEOPLE GO TO AN EARLY GRAVE AND GET SO ILL AND CONFUSED. THANK YOU ALL and keep it up.
My levels are now normal the only other thing i do is intermittent fasting eating and drinking between 11am-7pm only water in between. My doctor is amazed: cholesterol from 12.1 to 5.8 and triglyceride from 5 to 3.8
Linda

Even if this was true (no side effects with statins), we are still having these side effects (in our head maybe). They are still affecting our way of life and our health (be it psychological or not). I don’t want to take the chance.

I have been on statins 25 yrs. Yes it does cause terrible muscle cramps and pain in every muscle in your body, and joint pain. They have tried me on every one they have out; they all do the same thing to my body!! The only way I can half way tolerate it is to take the lowest mg prescribed.
Sometimes I think it is not worth the benefit for all I have to suffer to lower my cholesterol. Now I am becoming very forgetful and have diabetes!

This is why I do not trust “scientific studies.” It is lying with statistics. The practice of medicine has been quantified and often on false pretenses. Cholesterol is a good thing if you want to live long and keep your marbles and healthy hormones. It does not cause heart attacks but a whole generation of doctors doesn’t seem to know it.

After years of statin use, I developed neuropathy and cataracts (I am a sun hater by the way.) Also after two years of weight training I still have weakness in my legs.

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