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Kicking Cymbalta Is Painful

Q. My doctor prescribed Cymbalta for the pain of fibromyalgia, but it did not alleviate the pain at all. Instead, it made me feel like a zombie. I had no energy or motivation, but I did have insomnia.

The worst thing was stopping the drug. I had anxiety, panic, awful dizziness, increased pain and even more insomnia for weeks. Please warn your readers.

A. Duloxetine (Cymbalta) was originally approved as an antidepressant. More recently, however, it has been promoted for chronic pain associated with osteoarthritis, fibromyalgia, neuropathy and lower back problems.

The Medical Letter on Drugs and Therapeutics (May 2, 2011) concluded, “Duloxetine’s (Cymbalta) superiority over placebo for treatment of chronic low back pain and osteoarthritis appears to be modest at best.”

Other readers also report difficulty stopping Cymbalta. One woman wrote, “Our daughter’s life has almost been ruined in her attempt to withdraw from that drug. She is almost an invalid as a result. Kindly send me your Guide to Dealing with Depression and any information on withdrawing from Cymbalta.”

Suddenly stopping drugs such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), paroxetine (Paxil), sertraline (Zoloft) and venlafaxine (Effexor) can lead to disorientation, dizziness, nausea, insomnia, headaches and other symptoms of withdrawal. We discuss this problem in our Guide. Anyone who would like a copy, please send $3 in check or money order with a long (no. 10) stamped (64 cents), self-addressed envelope: Graedons’ People’s Pharmacy, No. E-7, P. O. Box 52027, Durham, NC 27717-2027. It can also be downloaded for $2 here.

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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