As complications from proton pump inhibitors (PPIs) accumulate, people are getting worried. Millions of people take medications like dexlansoprazole, esomeprazole, lansoprazole, omeprazole, pantoprazole and rabeprazole. Is there any way to stop acid suppressing drugs without going through heartburn hell?
How Can You Get Off a PPI?
Q. I am really upset about the latest information regarding the dangers of long-term use of PPI heartburn drugs. I have been taking one for several years for reflux.
I tried going off it and had terrible long-lasting heartburn the next day. I am going to try going off it again. Can I use something like Tums when I get that horrible heartburn, or do you have other suggestions?
A. Proton pump inhibitors (PPIs) are popular for many digestive woes. They used to be perceived as super safe, but over time disturbing complications have surfaced. These include kidney damage, dementia, fractures, pneumonia, diarrhea and certain nutritional deficiencies (iron, vitamin B12 and magnesium).
Rebound Hyperacidity from Acid Suppressing Drugs:
As you discovered, stopping PPIs suddenly can lead to rebound heartburn that may last for weeks. To avoid this withdrawal, you might wean yourself gradually and add antacids, DGL (deglycyrrhizinated licorice), ginger and probiotics.
Here are some stories from other people who have gone through what you have:
Anyone who needs to stop acid suppressing drugs will need to go slow and consult a health professional. This may not be a do-it-yourself project. Here is a link to multiple strategies for stopping heartburn drugs without suffering extreme pain.
Our Guide to Digestive Disorders provides more specific details about a variety of options for phasing off PPIs and alternate approaches for treating heartburn.
