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Omeprazole Side Effects Motivate Difficult Discontinuation of Heartburn Drug

Q. I have been on omeprazole for heartburn but it has led to high blood pressure and headaches. I have also developed osteoporosis.

I am desperate to get off this drug, but every time I stop the heartburn is intense. Recommendations?

A. New research suggests that long-term use of acid-suppressing drugs may reduce blood vessel flexibility and raise the risk of heart disease (Circulation, online, July 3, 2013). Stopping drugs like lansoprazole, omeprazole or pantoprazole suddenly, however, can trigger rebound hyperacidity.

We are sending you our Guide to Digestive Disorders with details about how to wean yourself from such drugs using DGL, ginger and persimmon tea. Gradual tapering of the PPI dose over six weeks is advised.

CAH offered this advice from experience:

“It is possible to get off these drugs, but a challenge. I made several attempts which ended unsuccessfully, as the discomfort would send me back to the Prilosec after a few days. The more I read about the possible results of long term use (it is recommended only for SHORT TERM use) –the more determined I was to stop. I used a very slow taper, over several months–until I was down to no Prilosec. Now, if I feel a hint of heartburn, over the counter Zantac, Tums, or Pepto-Bismol do the trick.

“Also, I have raised the head of my bed, don’t wear tight clothes, don’t overeat–I am especially careful with fats or spicy foods, etc. The first couple of weeks, there was some discomfort as I did the taper, but I was determined to stick it out this time. It was easier and easier as time passed. By the way, my doc didn’t believe in the ‘rebound’ effect–I’m not sure he is convinced yet. He said he never heard of it.

“There are lots of other hints here on The People’s Pharmacy if you search about–it was very helpful to me both before I began the process and during.”

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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