Overview

Buspirone is an anti-anxiety agent that is unrelated to benzodiazepines or other anti-anxiety medicines. It is prescribed for the management of anxiety disorders or for short-term relief of symptoms such as jitteriness, tremor, restlessness, heart pounding, sweating, dizziness, worry, fear, rumination, distractibility, or insomnia.

Buspirone does not seem to cause tolerance or dependence. Some results may be seen after a week of treatment, but optimum benefit is seen only after three or four weeks.

Adverse Reactions

Side Effects

Side effects associated with BuSpar often may include dizziness, drowsiness, nausea, headache, and nervousness.

Do not drive, operate machinery or undertake any activity that requires close attention until you are certain that BuSpar has not impaired coordination or judgment.

Other possible reactions include insomnia, dry mouth, fatigue, visual problems, weakness, digestive distress, diarrhea, constipation, lightedheadedness, confusion, anger, excitement, or depression. Report any symptoms to your physician promptly.

Interactions

Buspirone must not be taken within two weeks of an MAO inhibitor such as phenelzine, isocarboxazid, procarbazine, tranylcypromine, transdermal selegiline (Eldepryl, Emsam) or the antibiotic linezolid (Zyvox).

The tuberculosis drug rifampin or the herb St. John’s wort might speed elimination of buspirone from the body, which could reduce its effectiveness. Grapefruit, on the other hand, can boost blood levels and increase the risk of side effects.

Weight loss drugs such as lorcaserin or sibutramine could interact dangerously with buspirone to cause serotonin syndrome.

In general, buspirone should be taken by patients on medicines for psychiatric conditions (antidepressants, antipsychotics) only if they are followed very carefully.

Other Drugs That May Interact with Buspirone

  • amiodarone (Cordarone) for heart rhythm irregularities
  • antibiotics such as ciprofloxacin (Cipro), erythromycin or telithromycin (Ketek)
  • antifungal drugs such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil) or voriconazole (Vfend)
  • blood pressure medicines such as diltiazem (Cardizem, Dilt-CD) or verapamil (Calan, Covera-HS, Verelan)
  • HIV medications such as atazanavir (Reyataz), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), saquinavir (Fortovase, Invirase) or tipranavir (Aptivus)

Check with your pharmacist and physician to make sure buspirone is safe in combination with any other medicines or herbs you take.

Taking the Medicine

BuSpar is taken three times a day. Food has some effect on the medicine, so be consistent in the way you take it.

The manufacturer suggests it is prudent not to drink alcohol while taking buspirone.

It's almost Black Friday at The People's Pharmacy!

Black Friday at People's Pharmacy 2017
Days
Hours
Minutes
Seconds
View Specials Now

Get The Graedons' Favorite Home Remedies Health Guide for FREE

Join our daily email newsletter with breaking health news, prescription drug information, home remedies AND you'll get a copy of our brand new full-length health guide — for FREE!

What Do You Think?

We invite you to share your thoughts with others, but remember that our comment section is a public forum. Please do not use your full first and last name if you want to keep details of your medical history anonymous. A first name and last initial or a pseudonym is acceptable. Advice from other commenters on this website is not a substitute for medical attention. Do not stop any medicine without checking with the prescriber. Stopping medication suddenly could result in serious harm. We expect comments to be civil in tone and language. By commenting, you agree to abide by our commenting policy and website terms & conditions. Comments that do not follow these policies will not be posted.

Your cart

Total
USD
Shipping and discount codes are added at checkout.