Monopril is one of a group of drugs that includes Vasotec and Capoten. These
medications are called ACE inhibitors because they affect an enzyme
(angiotensin-converting enzyme) important in regulating blood pressure.
Monopril is often used to treat high blood pressure; it may also be
prescribed in combination with other drugs to treat some types of heart
failure.
ACE inhibitors, including Monopril, can reduce
kidney function, particularly in people who already have kidney problems.
Regular monitoring for both kidney and liver is essential.
People on
Monopril have experienced headache, dizziness, fatigue, a dry persistent cough
not relieved by cough medicine, or nausea.
Other side effects reported
include diarrhea, flatulence and heartburn.
In rare cases hemoglobin
levels drop slightly. Report any symptoms to the physician promptly.
Monopril, like other ACE inhibitors, is not recommended during pregnancy.
Notify the doctor if you suspect you have become pregnant and avoid the drug if
you are nursing.
In general, it is important to avoid potassium
supplements, including low-sodium salt substitutes, when taking a drug like
Monopril.
Diuretics such as Dyazide,
Aldactazide and Moduretic which preserve potassium can also cause dangerous
elevations in potassium when taken with Monopril.
Other diuretics may
also interact with Monopril. So might the psychiatric drug lithium or the heart
drug Lanoxin.
Check with your doctor and pharmacist to make sure Monopril is safe in
combination with any other drugs you take.
ACE inhibitors like Monopril can make people feel dizzy or faint, especially during the first few days of taking the medicine. Be cautious when sitting or standing up. If you faint, let your doctor know.
When you start taking Monopril, be alert for a rare but serious reaction.
Some people have experienced swelling of the face, lips, tongue and throat which can make breathing difficult if not impossible. This requires immediate emergency treatment.
African-Americans may be somewhat more susceptible to this unusual adverse effect. They may also be less likely to get the full expected response to Monopril. If you are African-American, be sure to discuss benefits and risks with your physician.
Monopril may be taken when convenient, with or without food.
Do not stop taking Monopril
suddenly, as this could lead to complications.