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Evaquin Leads to Achilles Tendon Problems

Newspaper Columns, Pharmacy Q&A August 24, 2007

Evaquin Leads to Achilles Tendon Problems

Q. Is there anyone collecting and disseminating information on personal experiences with Achilles tendonitis caused by the antibiotic Levaquin? I have had this problem in both legs for several weeks after receiving the medication.  My doctor seems not to have heard of this complication until now.

As a consumer I have found considerable information on the Internet, but nothing regarding the time frame for relief from this painful condition.

A. Unfortunately, inflammation and in rare cases even rupture of tendons, including the Achilles tendon at the back of the ankle, are possible side effects of Levaquin and similar antibiotics. We have heard from other readers with similar problems. One person’s experience suggests the time frame for recovery may be months rather than weeks: “I took 750 mg of Levaquin for a sinus infection for 9 days. I got rid of the sinus infection but have been dealing with tendinopathy in my legs and one shoulder for the past three months.”

Reader Comments

I have taken Levaquin 500 mg tablets for 11 days (until 2 days ago) against pneumonia.

I have developed severe pain in my achilles tendons (mostly on the left side ). I can hardly walk in the morning. Not having had any problems before I could not figure whatever could be the reason for this problem, especially since I have been doing stretching exercises for years.

My wife and I both have Chronic Lyme disease. Levaquin is one of the medicines given orally and by IV to treat Lyme and other tick-borne co-infections. Several people that we have spoken with personally have taken Levaquin and experienced serious tendon problems.

My wife has a tendon that has split (per MRI results), and she was told it was probably from taking the Levaquin. She is disabled at this point and we have found nothing to help reverse the situation. I have also read about tendon problems from use of Levaquin on several forums related to Lyme disease.

I was diagnosed in an emergency room with pneumonia after some mysterious symptoms that included blood pressure over 200 and pulse of 110 with sputum containing blood. I was given a prescription for Levaquin for the "pneumonia."

After two days, there was tremendous swelling of my right arm and left leg.

There was acute weakness and pain of the left Achilles tendon. My left leg bothers me to this day--about 8 months later.

I was in doubt about the pneumonia diagnosis to begin with, and still am. Doubly in doubt about the prescription, since I have never been allergic or had any reaction to drugs in 85 years.

I have had a prostate problem for years. I was often given Cipro or Levaquin for frequent kidney infections. I was also prescribed Levaquin after two prostate surgeries.

During this period I noticed I was having pains in my knees that kept getting worse, but I did not associate them with the use of the two drugs. Following one particularly painful bout, I found it necessary to use a cane to walk from the parking lot to work. I even consulted an orthopedic doctor who recommended surgery. However, after an MRI, he said I could probably put it off until my 60s, about 5 years away.

I still have knee pain off and on, but I have discovered that if I stay away from Levaquin and Cipro my problem is not as bad. I blame these two medications for the acute pain I have experienced in the past.

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Joe Graedon is a pharmacologist. Teresa Graedon holds a doctorate in medical anthropology and is a nutrition expert. Their syndicated radio show can be heard on public radio. In their column, Joe and Teresa Graedon answer letters from readers. Write to them in care of this newspaper or e-mail them via their Web site: www.PeoplesPharmacy.com.

© 2007 King Features Syndicate, Inc.