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Generic Name: Zolpidem
Brand Name(s):
Information updated: April 1, 2000
Overview
Ambien is the first in a new class of sleeping medicines. It is prescribed
for the short-term treatment of insomnia.
Studies indicate that the
stages of sleep approach normal in patients on Ambien, and there is a low
incidence of next-day hangover.
Side Effects and Interactions
People on Ambien may experience daytime
drowsiness, dizziness, diarrhea, nausea, vomiting or headache.
Other
side effects reported include lethargy, weakness, drugged feelings, amnesia, dry
mouth, constipation, allergy and sinusitis.
Because this medication is
still quite new, some rare reactions may not yet have shown up. Be sure to
report any symptoms to your physician promptly.
Relatively few studies
have considered Ambien in combination with other medications.
Ambien
interacts with alcohol, which should generally be avoided by everyone taking
sleeping pills.
Antianxiety medicines like Xanax and other sleeping
pills, such as Dalmane or Halcion, might magnify the effects of Ambien.
This sleeping pill can reduce peak blood levels of Tofranil (imipramine)
by 20 percent and decrease alertness.
Increased impairment has also been
reported when Thorazine is combined with Ambien.
Because of the animal
research showing that lemon balm extract can potentiate barbiturate action, the
herb should be used only with caution, if at all, in combination with
Ambien.
Check with your doctor and pharmacist to make sure Ambien is safe
in combination with any other drugs or herbs you take.
Special Precautions
Older people are more sensitive to Ambien and usually require a lower dose.
Insomnia often occurs as a result of physical or psychological illness. While Ambien can shorten the time it takes to fall asleep and lengthen the time a person sleeps, it can't help correct any underlying problems, which should be diagnosed and treated appropriately.
Although there is no evidence that Ambien produces physical dependence or addiction, anyone with a history of substance abuse should be monitored carefully while on this or any other sleeping pill.
Taking the Medicine
Ambien works very quickly. It should be taken on an empty stomach immediately before going to bed.
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Joe Graedon is a pharmacologist. Teresa Graedon holds a doctorate in medical anthropology and is a nutrition expert. Their syndicated radio show can be heard on public radio.
© 2000
Reader Comments
I take the generic form of Ambien and find that it does not work nearly as well. Has this been a problem for other people?
Posted by: CH | April 29, 2008 10:01 AM
I'm an 'older person' (mid-60s) and still need the full dose to fall/stay asleep.
The only doctor's opinion I'd trust is one who has "walked a mile in my shoes."
Posted by: Lee Shore | May 8, 2008 7:34 PM