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Generic Name: Thyroid hormones
 

Brand Name(s):

Information updated: April 1, 2000

Overview

Thyroid hormones come in a variety of formulations and brand names.

Natural products made of dried thyroid glands from beef and pork are sold as Armour Thyroid, Thyroid Strong and Thyroid USP.

They are generally quite inexpensive, but dosage levels may vary. That is why endocrinologists usually prescribe synthetic products such as Synthroid or Levothroid.

When people develop a sluggish thyroid gland they often feel tired and weak. They may become constipated, sensitive to cold or anemic.

They may also suffer with dry skin and hair, thick brittle fingernails and have shortness of breath when they exercise.

Some people report clumsiness, weight gain, or puffy eyes.

Thyroid problems are diagnosed with blood tests. The best is one that measures thyroid stimulating hormone, or TSH.

This test also helps determine the proper dose of thyroid hormone for treatment.

Side Effects and Interactions

Side effects of thyroid replacement therapy are rare if the dose is appropriate.

Specialists recommend beginning treatment with a low dose and gradually increasing it until symptoms of underactive thyroid disappear and the TSH blood test is normal.

This may initially require blood tests every four to six weeks and good communication with the doctor.

Too much thyroid hormone can lead to complications such as osteoporosis and heart disease.

Signs of overdose include insomnia, heart palpitations, jitteriness, rapid heart beat, increased sweating, higher blood pressure, changes in appetite, and reduced menstrual flow.

Other adverse reactions of excessive thyroid levels include tremor, headache, diarrhea, and weight loss. Report any such symptoms to your physician promptly.

A number of medications may interact with thyroid hormone or alter the tests that detect thyroid problems.

People taking estrogen, asthma medicines, decongestants (including those found in over-the-counter cold or flu remedies), antidepressants, certain cholesterol lowering drugs, blood thinners such as Coumadin or heart medicine like digoxin should check with a physician or pharmacist.

In theory, the herb guggul might counteract thyroid-suppressing drugs or increase the effect of thyroid hormones. Monitoring thyroid function is prudent.

Licorice may alter the required dose of levothyroxine because of its impact on the thyroid gland.

Never stop taking thyroid hormone without first checking with your health care provider.

Special Precautions

Too much thyroid hormone can make a person more susceptible to osteoporosis or weakened bones.

You may wish to discuss with your doctor whether you need tests to monitor bone density.

Thyroid replacement is usually needed for the rest of one's life, and stopping the medicine suddenly could precipitate symptoms of inactive thyroid.

Don't discontinue any thyroid hormone without your doctor's supervision. It is usually best to stick with one formulation rather than switching from one brand to another frequently.

Taking the Medicine

The usual recommendation is to take thyroid hormone before breakfast.

Although this hormone is probably best taken on an empty stomach, it is more important to take it at the same time every day to maintain a constant level in your body.

Do not take this medication with iron pills, as they can interfere with proper absorption.

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Reader Comments

The comments below are provided by the users of this site and not by The Peoples Pharmacy or the Graedons. Please also remember that nothing contained in this site is intended as a substitute for medical advice.

When I was diagnosed with underactive thyroid, I was prescribed Synthroid. This did not seem to work well for me, so I switched to Armour Thyroid, which other than the smell was working well for me.

I had moved and although my new doctor kept me on Armour, she thought it best if I went with the Synthroid as it was easier to control.

I do not feel as well. I am always cold, dry hair and skin. I am also taking Allegra, Nexium, Lovaza, Zoloft, Zocor, Boniva and Metoprolol. Most are the Generic Brand. I also take Citracal, Vitamin D, Centrum Silver and Ester C. I occasionally have a dizzy spell and unsteady on my feet.

Should I go back to Armour?

What are the interactions between all these meds and vitamins? Thank you for your response.

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Joe Graedon is a pharmacologist. Teresa Graedon holds a doctorate in medical anthropology and is a nutrition expert. Their syndicated radio show can be heard on public radio.

© 2000

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