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Generic Name: Nizatidine
Brand Name(s):
Information updated: April 1, 2000
Overview
Axid is a popular treatment for ulcers that helps them clear up rapidly. It
works in part by suppressing the secretion of stomach acid by blocking histamine
receptors in the digestive tract (H2 receptors).
It is also used to
treat the severe heartburn called reflux esophagitis, and may be prescribed as
maintenance therapy to keep ulcers from coming back.
Side Effects and Interactions
Side effects associated with Axid are uncommon.
Some people experience rash or anemia.
Other reactions reported
occasionally include diarrhea, headache, dizziness, muscle aches and weakness.
Report any symptoms to your physician promptly.
Axid appears to interact
with very few other medications compared to its predecessor Tagamet.
People who take high doses of aspirin may find blood levels of this
salicylate increase if they start taking Axid as well. Check with your
pharmacist and physician before taking other medicines in combination with
Axid.
Special Precautions
Patients taking H2 blockers like Axid or Zantac have higher levels of certain microorganisms in their stomachs than would normally survive there.
Scientists do not yet know whether these bacteria have negative long-term consequences, but it appears that vitamin C and E might provide some measure of protection.
Axid is eliminated almost completely by the kidneys. People with kidney problems may need the doctor to adjust the dose downward.
Taking the Medicine
Axid is usually taken once a day at bedtime. Absorption is slightly lower when this capsule is
taken with food, and antacids also reduce absorption slightly.
Axid tablets should be kept
away from heat, cold, light and moisture. The container should be capped very tightly.
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Joe Graedon is a pharmacologist. Teresa Graedon holds a doctorate in medical anthropology and is a nutrition expert. Their syndicated radio show can be heard on public radio.
© 2000