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Generic Name: Isosorbide mononitrate, extended release
Brand Name(s):
Information updated: April 1, 2000
Overview
Imdur is related to an older drug, isosorbide dinitrate, which has long been
prescribed to treat angina. This medicine helps the blood vessels relax, and
this puts less pressure on the heart.
Isosorbide mononitrate is also
available under two other brand names: Ismo and Monoket. The sustained action of
Imdur sets it apart.
These medicines are used to prevent angina; they do
not act quickly enough to be helpful in treating an acute attack.
Side Effects and Interactions
Imdur may cause headache in many of the people
who take it.
The headache is closely linked to the beneficial effects of
the drug and can't easily be avoided in susceptible individuals. It can,
however, be successfully treated with either aspirin or acetaminophen.
Other side effects include dizziness, nausea, vomiting, changes in heart
rhythm, rash or itching, stomach pain, weakness, and agitation.
A
dangerous blood condition called methemoglobinemia occurs very rarely. Report
any symptoms to the physician promptly.
Imdur may interact with certain
other drugs. The manufacturer recommends avoiding alcohol completely and
adjusting the dose of calcium channel blockers.
Check with your doctor
and pharmacist to make sure Imdur is safe in combination with any other drugs
you take.
Special Precautions
This medicine is not to be taken during a heart attack or an episode of congestive heart failure.
Very low blood pressure, particularly upon sitting or standing up suddenly, may be triggered by isosorbide mononitrate.
Patients should use caution when changing position.
Taking the Medicine
Imdur tablets are usually given in the morning right after rising.
They should not be
chewed or crushed, although if dosing requires it, they may be broken in half.
Swallow with
half a glass of liquid.
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Joe Graedon is a pharmacologist. Teresa Graedon holds a doctorate in medical anthropology and is a nutrition expert. Their syndicated radio show can be heard on public radio.
© 2000
Reader Comments
I am experiencing very sore throat about 2 hours after taking generic Indur 30MG ER.
The doctor's office dismissed it as being caused by some other (unknown cause). I have switched to taking it from morning until dinnertime to test the effect.
It is real and painful. Is it potentially dangerous?
Posted by: WJR | October 16, 2007 11:44 PM