Drug Library
Generic Name: Fexofenadine
Brand Name(s):
Information updated: April 1, 2000
Overview
Allegra is a relatively new nonsedating antihistamine used to treat
allergies such as hay fever. It alleviates symptoms such as runny nose, itchy,
watery eyes and sneezing.
Allegra was actually developed from a
metabolite of Seldane. It is supposed to provide the anti-allergy benefits
without the heart rhythm disturbances that can make Seldane hazardous.
Side Effects and Interactions
Side effects of Allegra are uncommon, but in
studies 2.5% of the volunteers on Allegra came down with a cold or the flu.
Other reactions they reported included indigestion, menstrual cramps,
fatigue and, in a few people, drowsiness. Report any symptoms to the physician
promptly.
Both erythromycin and Nizoral can change blood levels of
Allegra, making them go higher and last longer. But because Allegra does not
seem to affect the heart, no negative results have been noted.
As more
information accumulates on this new medication, further interactions may be
uncovered.
Check with your pharmacist and physician to make sure Allegra
is safe in combination with any other drugs you take.
Special Precautions
People with kidney problems may not eliminate Allegra efficiently and may need a lower dose.
Taking the Medicine
Allegra is taken two times a day. The capsules should be kept at room temperature and away from moisture.
Joe Graedon is a pharmacologist. Teresa Graedon holds a doctorate in medical anthropology and is a nutrition expert. Their syndicated radio show can be heard on public radio.
© 2000