Drug Library
Generic Name: Cefadroxil
Brand Name(s): Duricef, Ultracef
Information updated: April 1, 2000
Overview
Duricef belongs to a class of potent antibiotics called cephalosporins. It may also be prescribed as Ultracef.
This drug works against a wide variety of germs, including staphylococcus and Group A beta-hemolytic streptococcus. It is used to treat infections of the urinary tract, skin, throat and tonsils.
Cephalosporins are broad spectrum medicines that were originally discovered in one of the world's most unlikely locations.
A fungus found close to a sewer outlet along the coast of Sardinia turned out to cure a number of nasty infections. From this chance observation many extraordinary antibiotics have been developed.
Side Effects and Interactions
Side effects from cephalosporin-type antibiotics are generally mild. Nevertheless, Duricef can cause digestive tract discomfort, with diarrhea, nausea or vomiting.
If you develop diarrhea contact your physician, as it may be a warning of drug-induced colitis.
Other infrequent reactions to be aware of include rash, itching, swelling of the face and throat, vaginitis and yeast infections.
Duricef may affect laboratory test results. Liver enzymes may become elevated and false-positive results may show up on a blood test for certain anemias or lupus. Make sure that the laboratory personnel are aware you are taking Duricef if you have blood drawn.
And remember to report any symptoms or suspected side effects of cephalexin to your physician promptly.
Special Precautions
If you are allergic to penicillin-type antibiotics, alert your physician immediately. Some people who are sensitive to penicillin may also react to cephalosporins like Duricef.
Symptoms such as breathing difficulty, wheezing, sneezing, hives, itching, and skin rash require immediate emergency treatment.
Life-threatening anaphylactic shock may produce an inability to breathe and cardiovascular collapse and can occur within minutes of exposure.
If you have reacted to another cephalosporin, such as Keflex, you should avoid Duricef.
People with kidney problems should receive Duricef only under careful medical supervision, as the dosage will most likely have to be modified to prevent toxicity.
Taking the Medicine
Duricef may be taken with or without food. It may cause less stomach upset if taken with meals.
Joe Graedon is a pharmacologist. Teresa Graedon holds a doctorate in medical anthropology and is a nutrition expert. Their syndicated radio show can be heard on public radio.
© 2000