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How Vitamin D Deficiency Contributes to Diabetes and Heart Disease

Immune system cells deprived of vitamin D carry fat and deposit it in artery walls.

Some epidemiological studies have shown that two chronic conditions, heart disease and type 2 diabetes, are more common in people with low levels of vitamin D.

Now scientists have uncovered some important clues to explain this connection. The researchers used special mice that can’t utilize vitamin D normally to reduce inflammation.

These animals churned out too much glucose, became resistant to insulin and developed atherosclerotic plaques in their arteries. In these animals, the immune cells deprived of vitamin D started transporting fat. The artery walls and the liver became chronically inflamed.

Will Supplementation Work in People?

The next step will be to test people with risk factors for metabolic disorders to see whether vitamin D supplementation will be able to reduce their chance of developing disease.

Cell Reports, online March 19, 2015

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About the Author
Joe Graedon is a pharmacologist who has dedicated his career to making drug information understandable to consumers. His best-selling book, The People’s Pharmacy, was published in 1976 and led to a syndicated newspaper column, syndicated public radio show and web site. In 2006, Long Island University awarded him an honorary doctorate as “one of the country's leading drug experts for the consumer.”.
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